Search Results - "KURAMOCHI, Mizuki"

Acetaminophen-Induced Rat Hepatotoxicity Based on M1/M2-Macrophage Polarization, in Possible Relation to Damage-Associated Molecular Patterns and Autophagy by Tsuji, Yuka, Kuramochi, Mizuki, Golbar, Hossain M, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…Overdose of acetaminophen (APAP), an antipyretic drug, is an important cause of liver injury. However, the mechanism in the rat model remains undetermined. We…”
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Involvement of neutrophils in rat livers by low-dose thioacetamide administration by KURAMOCHI, Mizuki, IZAWA, Takeshi, KUWAMURA, Mitsuru, YAMATE, Jyoji

“…The administration with high dose (close to LD50) of thioacetamide (TAA), a hepatotoxicant used widely to induce experimental liver lesions, develops…”
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Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts by Imai, Toshio, Yoshida, Hiroshi, Machida, Yukino, Kuramochi, Mizuki, Ichikawa, Hitoshi, Kubo, Takashi, Takahashi, Mami, Kato, Tomoyasu

“…Patient-derived xenograft (PDX) tumor models are known to maintain the genomic and phenotypic profiles, including the histopathological structures, of the…”
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Appearance of Heterogeneous Macrophages During Development of Isoproterenol-Induced Rat Myocardial Fibrosis by Koga, Masaaki, Karim, Mohammad Rabiul, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…Macrophages appearing in lesions are polarized toward M1 (for inflammation) and M2 (for anti-inflammation/fibrosis) types. We analyzed immunophenotypes of…”
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Immunohistochemical characterization of myofibroblasts appearing in isoproterenol-induced rat myocardial fibrosis by KOGA, Masaaki, KURAMOCHI, Mizuki, KARIM, Mohammad Rabiul, IZAWA, Takeshi, KUWAMURA, Mitsuru, YAMATE, Jyoji

“…Fibrotic lesion is formed by myofibroblasts capable of producing collagens. The myofibroblasts are characterized by immunoexpressions of vimentin, desmin and…”
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Characterization of Immature Myofibroblasts of Stellate Cell or Mesenchymal Cell Origin in D-Galactosamine-Induced Liver Injury in Rats by Rahman, Nahid, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…Lesions of D-galactosamine (D-GalN)-induced hepatotoxicity resemble those of human acute viral hepatitis. This study investigated hepatic mesenchymal cells…”
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M1/M2-macrophage Polarization-based Hepatotoxicity in d-galactosamine-induced Acute Liver Injury in Rats by Rahman, Nahid, Pervin, Munmun, Kuramochi, Mizuki, Karim, Mohammad R., Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…d-galactosamine (d-GalN) is a well-known hepatotoxic agent that causes liver injury. Conversely, hepatic macrophages play a crucial role in maintaining liver…”
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Effects of dexamethasone on hepatic macrophages in normal livers and thioacetamide-induced acute liver lesions in rats by Hada, Noa, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…Resident and infiltrative macrophages play important roles in the development of pathological lesions. M1/M2 macrophage polarization with respective CD68 and…”
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Characterization of Macrophages and Myofibroblasts Appearing in Dibutyltin Dichloride–Induced Rat Pancreatic Fibrosis by Hashimoto, Ai, Karim, Mohammad Rabiul, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…Macrophages and myofibroblasts are important in fibrogenesis. The cellular characteristics in pancreatic fibrosis remain to be investigated. Pancreatic…”
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Participation of Somatic Stem Cells, Recognized by a Unique A3 Antibody, in Mucosal Epithelial Regeneration in Dextran Sulfate Sodium (DSS)–Induced Rat Colonic Lesions by Nishina, Hironobu, Katou-Ichikawa, Chisa, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…A3, generated as a monoclonal antibody against rat malignant fibrous histiocytoma cells, recognizes somatic stem cells in rats. We analyzed the distribution of…”
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Differential effects of class I antiarrhythmic drugs on the guinea pig pulmonary vein myocardium: Inhibition of automatic activity correlates with blockade of a diastolic sodium current component by Irie, Masahiko, Hiiro, Haruhito, Kato, Shu, Kuramochi, Mizuki, Hamaguchi, Shogo, Namekata, Iyuki, Tanaka, Hikaru

“…The effects of class I antiarrhythmic drugs on the automaticity of isolated guinea pig pulmonary vein myocardia were investigated using microelectrode and…”
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Macrophage Populations and Expression of Regulatory Inflammatory Factors in Hepatic Macrophage-depleted Rat Livers under Lipopolysaccharide (LPS) Treatment by Pervin, Munmun, Karim, Mohammad Rabiul, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…To investigate the significance of the appearance of hepatic macrophages and expression of inflammatory factors in normal and macrophage-depleted livers,…”
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High mobility group box1 as a danger signal inducing the infiltration of neutrophils and macrophages in thioacetamide-induced rat liver injury by KURAMOCHI, Mizuki, KARIM, Mohammad Rabiul, IZAWA, Takeshi, KUWAMURA, Mitsuru, YAMATE, Jyoji

“…The liver, a major organ involved in substance metabolism, is highly susceptible to toxicity induced by chemicals and their metabolites. Although…”
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A novel splicing variant of small nucleolar RNA host gene 4 is a podocyte-selective non-coding RNA upregulated in response to puromycin aminonucleoside-induced podocyte injury by Horikawa, Aya, Yoneda, Tomomi, Yaoita, Eishin, Yamaguchi, Katsushi, Shigenobu, Shuji, Kuramochi, Mizuki, Yamate, Jyoji, Inui, Takashi, Ishibashi, Osamu

“…Podocytes are terminally differentiated cells that function as the glomerular filtration barrier in the kidney, and podocyte injury leads to serious…”
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Treatment with vonoprazan for 3 weeks is not inferior to 8 weeks for the management of gastric ESD: a multicenter noninferiority randomized study by Kato, Motohiko, Hosoe, Naoki, Gotoda, Takuji, Kusano, Chika, Kuramochi, Mizuki, Yoshida, Hideo, Kimoto, Yoshiaki, Okamura, Yukishige, Imaeda, Hiroyuki, Ito, Takafumi, Miyamoto, Yasuo, Horii, Toshiki, Mori, Hideki, Morohoshi, Yuichi, Ohno, Akiko, Kishino, Ryohei, Kubosawa, Yoko, Yoshimura, Kenichi, Yahagi, Naohisa, Kanai, Takanori

“…Background Vonoprazan , a potassium-competitive acid blocker (VPZ), significantly reduces postoperative bleeding after gastric ESD; however, there is no…”
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Transient Pulmonary Interstitial Lesions in Aquaporin-4-positive Neuromyelitis Optica Spectrum Disorder by Asato, Yuko, Kamitani, Toshiaki, Ootsuka, Kuniyuki, Kuramochi, Mizuki, Nakanishi, Kozo, Shimada, Tetsuya, Takahashi, Toshiyuki, Misu, Tatsuro, Aoki, Masashi, Fujihara, Kazuo, Kawabata, Yoshinori

“…We herein report the case of a 76-year old man with aquaporin-4-Immunoglobulin-G (AQP4-IgG)-positive neuromyelitis optica spectrum disorder (NMOSD), in whom…”
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The localization and distribution of cells labeled by a somatic stem cell-recognizing antibody (A3) in rat colon development; possible presence of a new cell type forming the intestinal stem cell niche by Nishina, Hironobu, Katou-Ichikawa, Chisa, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji

“…A3, generated as a monoclonal antibody against rat malignant fibrous histiocytoma (MFH)-derived cloned cells, recognizes somatic stem cells (bone-marrow/hair…”
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Diffuse leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund by KURAMOCHI, Mizuki, IZAWA, Takeshi, MORI, Mutsuki, SHIMAMURA, Shunsuke, SHIMADA, Terumasa, KUWAMURA, Mitsuru, YAMATE, Jyoji

“…Leiomyoma is the most common mesenchymal tumor in the gastrointestinal (GI) tract. Leiomyomas usually have a single or multinodular mass of various sizes, and…”
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Rat polyomavirus 2 infection in a colony of X-linked severe combined immunodeficiency rats in Japan by TANAKA, Miyuu, KURAMOCHI, Mizuki, NAKANISHI, Satoshi, KUWAMURA, Mitsuru, KURAMOTO, Takashi

“…Polyomaviruses (PyVs) infect a wide range of animals and provoke wasting diseases, particularly in immunosuppressed hosts. Recently, a novel Rattus norvegicus…”
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Diagnostic significance of secondary bacteremia in patients with COVID-19 by Nakagawara, Kensuke, Kamata, Hirofumi, Chubachi, Shotaro, Namkoong, Ho, Tanaka, Hiromu, Lee, Ho, Otake, Shiro, Fukushima, Takahiro, Kusumoto, Tatsuya, Morita, Atsuho, Azekawa, Shuhei, Watase, Mayuko, Asakura, Takanori, Masaki, Katsunori, Ishii, Makoto, Endo, Akifumi, Koike, Ryuji, Ishikura, Hiroyasu, Takata, Tohru, Matsushita, Yasushi, Harada, Norihiro, Kokutou, Hiroyuki, Yoshiyama, Takashi, Kataoka, Kensuke, Mutoh, Yoshikazu, Miyawaki, Masayoshi, Ueda, Soichiro, Ono, Hiroshi, Ono, Takuya, Shoko, Tomohisa, Muranaka, Hiroyuki, Kawamura, Kodai, Mori, Nobuaki, Mochimaru, Takao, Fukui, Mototaka, Chihara, Yusuke, Nagasaki, Yoji, Okamoto, Masaki, Amishima, Masaru, Odani, Toshio, Tani, Mayuko, Nishi, Koichi, Shirai, Yuya, Edahiro, Ryuya, Ando, Akira, Hashimoto, Naozumi, Ogura, Shinji, Kitagawa, Yuichiro, Kita, Toshiyuki, Kagaya, Takashi, Kimura, Yasuhiro, Miyazawa, Naoki, Tsuchida, Tomoya, Fujitani, Shigeki, Murakami, Koji, Sano, Hirohito, Sato, Yuki, Tanino, Yoshinori, Otsuki, Ryo, Mashimo, Shuko, Kuramochi, Mizuki, Hosoda, Yasuo, Hasegawa, Yoshinori, Ueda, Tetsuya, Takaku, Yotaro, Ishiguro, Takashi, Fujiwara, Akiko, Kuwahara, Naota, Kitamura, Hideya, Hagiwara, Eri, Nakamori, Yasushi, Saito, Fukuki, Kono, Yuta, Abe, Shinji, Ishii, Tomoo, Ohba, Takehiko, Kusaka, Yu, Watanabe, Hiroko, Masuda, Makoto, Watanabe, Hiroki, Kimizuka, Yoshifumi, Kawana, Akihiko, Kasamatsu, Yu, Hashimoto, Satoru, Okada, Yukinori, Takano, Tomomi, Katayama, Kazuhiko, Ai, Masumi, Kumanogoh, Atsushi, Sato, Toshiro, Tokunaga, Katsushi, Imoto, Seiya, Kitagawa, Yuko, Kimura, Akinori, Miyano, Satoru, Hasegawa, Naoki, Ogawa, Seishi, Kanai, Takanori, Fukunaga, Koichi

“…We investigated the occurrence of non-respiratory bacterial and fungal secondary infections, causative organisms, impact on clinical outcomes, and association…”
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