Search Results - "KUN, Larry E"

Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study by Merchant, Thomas E, Prof, Li, Chenghong, PhD, Xiong, Xiaoping, Prof, Kun, Larry E, Prof, Boop, Frederic A, MD, Sanford, Robert A, MD

“…Summary Background Therapy for ependymoma includes aggressive surgical intervention and radiotherapy administered by use of methods that keep the risk of…”
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Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation by Pui, Ching-Hon, Campana, Dario, Pei, Deqing, Bowman, W. Paul, Sandlund, John T, Kaste, Sue C, Ribeiro, Raul C, Rubnitz, Jeffrey E, Raimondi, Susana C, Onciu, Mihaela, Coustan-Smith, Elaine, Kun, Larry E, Jeha, Sima, Cheng, Cheng, Howard, Scott C, Simmons, Vickey, Bayles, Amy, Metzger, Monika L, Boyett, James M, Leung, Wing, Handgretinger, Rupert, Downing, James R, Evans, William E, Relling, Mary V

“…This large trial of acute lymphoblastic leukemia in children aimed to determine whether intensive systemic and intrathecal chemotherapy could obviate the need…”
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Primary Neurosurgery for Pediatric Low-Grade Gliomas: A Prospective Multi-Institutional Study From the Children's Oncology Group by Wisoff, Jeffrey H., Sanford, Robert A., Heier, Linda A., Sposto, Richard, Burger, Peter C., Yates, Allan J., Holmes, Emiko J., Kun, Larry E.

“…Abstract BACKGROUND: Central nervous system neoplasms are the most common solid tumors in children, and more than 40% are low-grade gliomas. Variable…”
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Hearing Loss After Radiotherapy for Pediatric Brain Tumors: Effect of Cochlear Dose by Hua, Chiaho, Ph.D, Bass, Johnnie K., Au.D, Khan, Raja, M.D, Kun, Larry E., M.D, Merchant, Thomas E., D.O., Ph.D

“…Purpose To determine the effect of cochlear dose on sensorineural hearing loss in pediatric patients with brain tumor treated by using conformal radiation…”
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A Retrospective Study of Surgery and Reirradiation for Recurrent Ependymoma by Merchant, Thomas E., D.O., Ph.D, Boop, Frederick A., M.D, Kun, Larry E., M.D, Sanford, Robert A., M.D

“…Purpose To report disease control for patients with recurrent ependymoma (EP) treated with surgery and a second course of radiation therapy (RT2 ). Patients…”
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Phase II Trial of Conformal Radiation Therapy for Pediatric Low-Grade Glioma by MERCHANT, Thomas E, KUN, Larry E, SHENGJIE WU, XIAOPINGXIONG, SANFORD, Robert A, BOOP, Frederick A

“…The use of radiotherapy in pediatric low-grade glioma (LGG) is controversial, especially for young patients. We conducted a phase II trial of conformal…”
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Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study by FOULADI, Maryam, STEWART, Clinton F, DEMUTH, Tim, KUN, Larry E, BOYETT, James M, GILBERTSON, Richard J, OLSON, James, WAGNER, Lars M, ONAR-THOMAS, Arzu, KOCAK, Mehmet, PACKER, Roger J, GOLDMAN, Stewart, GURURANGAN, Sridharan, GAJJAR, Amar

“…To estimate the maximum-tolerated dose (MTD), describe dose-limiting toxicities (DLTs), and characterize pharmacokinetic properties of MK-0752, a gamma…”
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Disease Control After Reduced Volume Conformal and Intensity Modulated Radiation Therapy for Childhood Craniopharyngioma by Merchant, Thomas E., DO, PhD, Kun, Larry E., MD, Hua, Chia-Ho, PhD, Wu, Shengjie, MS, Xiong, Xiaoping, PhD, Sanford, Robert A., MD, Boop, Frederick A., MD

“…Purpose To estimate the rate of disease control after conformal radiation therapy using reduced clinical target volume (CTV) margins and to determine factors…”
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Lack of Efficacy of Bevacizumab Plus Irinotecan in Children With Recurrent Malignant Glioma and Diffuse Brainstem Glioma: A Pediatric Brain Tumor Consortium Study by GURURANGAN, Sridharan, CHI, Susan N, KUN, Larry E, POUSSAINT, Tina Young, ONAR-THOMAS, Arzu, GILBERTSON, Richard J, VAJAPEYAM, Sridhar, FRIEDMAN, Henry S, PACKER, Roger J, ROOD, Brian N, BOYETT, James M

“…A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted in children with recurrent malignant glioma (MG) and intrinsic brainstem glioma…”
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Induction Chemotherapy and Conformal Radiation Therapy for Very Young Children With Nonmetastatic Medulloblastoma: Children's Oncology Group Study P9934 by ASHLEY, David M, MERCHANT, Thomas E, BUXTON, Allen, GEYER, Russell, KUN, Larry E, COLEMAN, Lee, POLLACK, Ian F, STROTHER, Douglas, TIANNI ZHOU, DUFFNER, Patricia, BURGER, Peter C, MILLER, Douglas C, LYON, Nancy, BONNER, Melanie J, MSALL, Michael

“…P9934 was a prospective trial of systemic chemotherapy, second surgery, and conformal radiation therapy (CRT) limited to the posterior fossa and primary site…”
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Treatment Outcomes in Black and White Children With Cancer: Results From the SEER Database and St Jude Children's Research Hospital, 1992 Through 2007 by PUI, Ching-Hon, DEQING PEI, JEHA, Sima, HUDSON, Melissa M, KUN, Larry E, MERCHANT, Thomas E, KOCAK, Mehmet, BRONISCER, Alberto, METZGER, Monika L, DOWNING, James R, WING LEUNG, EVANS, William E, PAPPO, Alberto S, GAJJAR, Amar, HOWARD, Scott C, CHENG CHENG, SANDLUND, John T, FURMAN, Wayne L, RIBEIRO, Raul C, SPUNT, Sheri L, RUBNITZ, Jeffrey E

“…Treatment outcome for black patients with cancer has been significantly worse than for their white counterparts. We determined whether recent improved…”
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Multi-Institution Prospective Trial of Reduced-Dose Craniospinal Irradiation (23.4 Gy) Followed by Conformal Posterior Fossa (36 Gy) and Primary Site Irradiation (55.8 Gy) and Dose-Intensive Chemotherapy for Average-Risk Medulloblastoma by Merchant, Thomas E., D.O., Ph.D, Kun, Larry E., M.D, Krasin, Matthew J., M.D, Wallace, Dana, M.S, Chintagumpala, Murali M., M.D, Woo, Shiao Y., M.D, Ashley, David M., M.B.B.S, Sexton, Maree, M.B.B.S, Kellie, Stewart J., M.B.B.S, Ahern, Verity, M.B.B.S, Gajjar, Amar, M.D

“…Purpose Limiting the neurocognitive sequelae of radiotherapy (RT) has been an objective in the treatment of medulloblastoma. Conformal RT to less than the…”
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Atypical Teratoid/Rhabdoid Tumors (ATRT): Improved Survival in Children 3 Years of Age and Older With Radiation Therapy and High-Dose Alkylator-Based Chemotherapy by TEKAUTZ, Tanya M, FULLER, Christine E, WALLACE, Dana, GILBERTSON, Richard J, GAJJAR, Amar, BLANEY, Susan, FOULADI, Maryam, BRONISCER, Alberto, MERCHANT, Thomas E, KRASIN, Matthew, DALTON, James, HALE, Gregory, KUN, Larry E

“…To describe clinical features, therapeutic approaches, and prognostic factors in pediatric patients with atypical teratoid/rhabdoid tumors (ATRT) treated at St…”
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Endocrine Outcomes for Children With Embryonal Brain Tumors After Risk-Adapted Craniospinal and Conformal Primary-Site Irradiation and High-Dose Chemotherapy With Stem-Cell Rescue on the SJMB-96 Trial by Laughton, Stephen J, Merchant, Thomas E, Sklar, Charles A, Kun, Larry E, Fouladi, Maryam, Broniscer, Alberto, Morris, E Brannon, Sanders, Robert P, Krasin, Matthew J, Shelso, John, Xiong, Zang, Wallace, Dana, Gajjar, Amar

“…To estimate the cumulative incidence of specific hormone deficiencies and the influence of hypothalamic-pituitary (HP) axis radiation dose in a cohort of…”
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Phase I Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory, or Progressive Primary CNS Tumors: Pediatric Brain Tumor Consortium Study PBTC-018 by WARREN, Katherine E, GOLDMAN, Stewart, JAKACKI, Regina, BOYETT, James M, KUN, Larry E, POLLACK, Ian F, FANGUSARO, Jason, SCHAIQUEVICH, Paula, STEWART, Clinton F, WALLACE, Dana, BLANEY, Susan M, PACKER, Roger, MACDONALD, Tobey

“…A phase I trial of lenalidomide was performed in children with recurrent, refractory, or progressive primary CNS tumors to estimate the maximum-tolerated dose…”
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Phase I Clinical Trial of Cilengitide in Children With Refractory Brain Tumors: Pediatric Brain Tumor Consortium Study PBTC-012 by MACDONALD, Tobey J, STEWART, Clinton F, KUN, Larry E, KOCAK, Mehmet, GOLDMAN, Stewart, ELLENBOGEN, Richard G, PHILLIPS, Peter, LAFOND, Deborah, TINA YOUNG POUSSAINT, KIERAN, Mark W, BOYETT, James M

“…A phase I trial of the antiangiogenesis agent cilengitide (EMD 121974), an alpha v beta 3,5 integrin antagonist, was performed to estimate the…”
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Clinical and Molecular Characteristics of Malignant Transformation of Low-Grade Glioma in Children by BRONISCER, Alberto, BAKER, Suzanne J, GAJJAR, Amar, GILBERTSON, Richard, FULLER, Christine E, WEST, Alina N, FRASER, Melissa M, PROKO, Erika, KOCAK, Mehmet, DALTON, James, ZAMBETTI, Gerard P, ELLISON, David W, KUN, Larry E

“…To analyze the clinical and molecular characteristics of malignant transformation (MT) of low-grade glioma (LGG) in children. The clinical, radiologic, and…”
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Phase I Trial of Lapatinib in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study by FOULADI, Maryam, STEWART, Clinton F, BLANEY, Susan M, ONAR-THOMAS, Arzu, SCHAIQUEVICH, Paula, PACKER, Roger J, GAJJAR, Amar, KUN, Larry E, BOYETT, James M, GILBERTSON, Richard J

“…To estimate the maximum-tolerated dose, dose-limiting toxicities (DLTs), and pharmacokinetic properties of lapatinib, a selective epidermal growth factor…”
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Extended Follow-up of Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia by Pui, Ching-Hon, Cheng, Cheng, Leung, Wing, Rai, Shesh N, Rivera, Gaston K, Sandlund, John T, Ribeiro, Raul C, Relling, Mary V, Kun, Larry E, Evans, William E, Hudson, Melissa M

“…Survivors of acute lymphoblastic leukemia who had been in complete remission for at least 10 years and had not received radiation therapy had a negligible risk…”
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Amifostine Protects Against Cisplatin-Induced Ototoxicity in Children With Average-Risk Medulloblastoma by FOULADI, Maryam, CHINTAGUMPALA, Murali, HALE, Gregory A, KASOW, Kimberly A, MERCHANT, Thomas E, MORRIS, Brannon, KRASIN, Matthew, KUN, Larry E, BOYETT, James M, GAJJAR, Amar, ASHLEY, David, KELLIE, Stewart, GURURANGAN, Sridharan, HASSALL, Tim, GRONEWOLD, Lindsey, STEWART, Clinton F, WALLACE, Dana, BRONISCER, Alberto

“…To determine the role of amifostine as a protectant against cisplatin-induced ototoxicity in patients with average-risk (AR) medulloblastoma treated with…”
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