Search Results - "KUMIHASHI, Mitsuru"
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Ethanol and Acetaldehyde After Intraperitoneal Administration to Aldh2-Knockout Mice-Reflection in Blood and Brain Levels
Published in Neurochemical research (01-05-2016)“…This paper reports, for the first time, on the analysis of ethanol (EtOH) and acetaldehyde (AcH) concentrations in the blood and brains of Aldh2-knockout…”
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Case report: An autopsy case of pilsicainide poisoning
Published in Frontiers in pharmacology (26-01-2023)“…We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and…”
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Case report: Fatal poisoning caused by additive effects of two barbiturates
Published in Frontiers in pharmacology (24-05-2023)“…A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of…”
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Ethanol and acetaldehyde differentially alter extracellular dopamine and serotonin in Aldh2-knockout mouse dorsal striatum: A reverse microdialysis study
Published in Neurotoxicology (Park Forest South) (01-01-2016)“…•Perfusion with 500mM EtOH in the dorsal striatum produced a profound increase in the levels of DA in both Aldh2-KO and WT mice.•In contrast, perfusion with…”
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5
Fatal poisoning case involving drug interaction due to the inhibition of cytochrome P450
Published in Vojnosanitetski pregled (2021)“…Introduction. Cytochrome P450 (CYP) enzymes are responsible for the metabolism of various drugs and chemicals. The forensic pathologist should consider not…”
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Comparison of histological findings and the results of energy-dispersive X-ray spectrometry analysis in experimental electrical injury
Published in Legal medicine (Tokyo, Japan) (01-03-2018)“…The X-ray intensity of copper (Kα) of the formalin-fixed tissues of the three groups. There are significant differences between the 5-s and control groups…”
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Application of energy dispersive X-ray fluorescence spectrometry (EDX) in a case of methomyl ingestion
Published in Forensic science international (10-04-2013)“…Abstract We applied energy dispersive X-ray fluorescence spectrometry (EDX) in a case of poisoning by methomyl, a carbamate pesticide. Quantitative GC/MS…”
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Findings for current marks: Histopathological examination and energy-dispersive X-ray spectroscopy of three cases
Published in Legal medicine (Tokyo, Japan) (01-09-2013)“…Abstract We describe herein three cases of electrocution. As most deaths caused by electricity are due to cardiac arrhythmia or paralysis of the respiratory…”
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Detection of chlorine and bromine in free liquid from the sphenoid sinus as an indicator of seawater drowning
Published in Legal medicine (Tokyo, Japan) (01-09-2015)“…Graphical abstract Chlorine (left) and bromine (right) concentrations of liquid from sphenoid sinuses in seawater drowning cases, freshwater drowning cases and…”
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10
Distinction between entrance and exit wounds by energy dispersive X-ray fluorescence spectrometry
Published in Legal medicine (Tokyo, Japan) (01-09-2016)“…Graphical abstract EDX spectrum of the skin samples from Case 1 (blue line, wound in anterior chest wall; red line, wound in back region)…”
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Comparison of measurement methods for carboxyhemoglobin in blood samples based on visible spectra with 17 institutions
Published in Forensic toxicology (01-07-2019)“…Purpose An inter-method variation experiment to evaluate visible spectrophotometric methods for determining carboxyhemoglobin (CO-Hb) in blood was performed in…”
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Simultaneous determination of methamphetamine and its metabolite, amphetamine, in urine using a high performance liquid chromatography column-switching method
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2007)“…We describe here a simple, precise, and highly sensitive method for the simultaneous determination of methamphetamine (MA) and amphetamine (AM) in urine using…”
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13
Cholinergic alterations following alcohol exposure in the frontal cortex of Aldh2-deficient mice models
Published in Brain research (12-10-2009)“…Abstract We investigated the effects of alcohol (EtOH) and acetaldehyde (ACe) on choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) in the…”
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14
Usefulness of intratracheal gas analysis in an autopsy case of helium inhalation
Published in Romanian journal of legal medicine (01-09-2013)Get full text
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15
Effect of direct infusion of acetaldehyde on dopamine and dopamine-derived salsolinol in the striatum of free-moving rats using a reverse microdialysis technique
Published in Archives of toxicology (01-02-2007)“…The effects of acetaldehyde (ACD) on dopamine (DA) and DA-derived salsolinol (SAL) levels were investigated in the striatum of freely moving rats. Dialysate…”
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16
Ethanol metabolism in ALDH2 knockout mice – Blood acetate levels
Published in Legal medicine (Tokyo, Japan) (01-04-2009)“…Abstract We described here blood acetate levels in aldehyde dehydrogenase 2 knockout (ALDH2 KO) male mice based on C57BL/6 J strain after ethanol (EtOH) dosing…”
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17
Microdialysis for the determination of acetaldehyde and ethanol concentrations in the striatum of freely moving rats
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05-12-2003)“…The subject of the present paper is the simultaneous determination of ethanol (EtOH) and acetaldehyde (AcH) concentrations in the striatum of freely moving…”
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18
Medico-legal investigation of chicken fat clot in forensic cases: Immunohistochemical and retrospective studies
Published in Legal medicine (Tokyo, Japan) (01-05-2008)“…Abstract Chicken fat clot (CFC), a fibrin-like substance, is sometimes found in the heart and large blood vessels in some autopsy cases. Reports of detailed…”
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Kerosene condenses in the trachea following inhalation
Published in Forensic toxicology (01-07-2024)“…Purpose We have investigated the absorption dynamics of petroleum fuel components from the analytical results of autopsy samples. Methods Post-mortem samples…”
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An autopsy case of BRONTM overdose with multiple drug ingestion
Published in Legal medicine (Tokyo, Japan) (01-09-2023)“…•A fatal overdose of BRONTM, an over-the-counter antitussive, with fluvoxamine was described.•Fluvoxamine, a potent cytochrome P450 (CYP)1A2 inhibitor, may…”
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