Search Results - "KUMAR, RAKESH K."

Resolvin E1 promotes resolution of inflammation in a mouse model of an acute exacerbation of allergic asthma by Flesher, Rylie P, Herbert, Cristan, Kumar, Rakesh K

“…Endogenous mediators, such as RvE1 (resolvin E1), promote resolution of an inflammatory response and have potential as novel therapeutic agents. In the present…”
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Iron-Nicotianamine Transporters Are Required for Proper Long Distance Iron Signaling by Kumar, Rakesh K., Chu, Heng-Hsuan, Abundis, Celina, Vasques, Kenneth, Rodriguez, David Chan, Chia, Ju-Chen, Huang, Rong, Vatamaniuk, Olena K., Walker, Elsbeth L.

“…The mechanisms of root iron uptake and the transcriptional networks that control root-level regulation of iron uptake have been well studied, but the…”
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Modeling TH2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma by Foster, Paul S., Maltby, Steven, Rosenberg, Helene F., Tay, Hock L., Hogan, Simon P., Collison, Adam M., Yang, Ming, Kaiko, Gerard E., Hansbro, Philip M., Kumar, Rakesh K., Mattes, Joerg

“…Summary In this review, we highlight experiments conducted in our laboratories that have elucidated functional roles for CD4+ T‐helper type‐2 lymphocytes (TH2…”
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Emerging roles of pulmonary macrophages in driving the development of severe asthma by Yang, Ming, Kumar, Rakesh K., Hansbro, Philip M., Foster, Paul S.

“…Review on innate immunity in the pathogenesis of severe asthma and mechanisms of glucocorticoid resistance. Asthma is recognized as a heterogeneous disorder,…”
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Respiratory viral infection, epithelial cytokines, and innate lymphoid cells in asthma exacerbations by Kumar, Rakesh K., Foster, Paul S., Rosenberg, Helene F.

“…Review of how viral infection of airway epithelial cells leading to release of Th2‐promoting cytokines may drive asthma exacerbations via activation of innate…”
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A model for the use of blended learning in large group teaching sessions by Herbert, Cristan, Velan, Gary M, Pryor, Wendy M, Kumar, Rakesh K

“…Although blended learning has the potential to enhance the student experience, both in terms of engagement and flexibility, it can be difficult to effectively…”
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A review on PV cells and nanocomposite‐coated PV systems by Rakesh Tej Kumar, K., Ramakrishna, M., Durga Sukumar, G.

“…Summary Solar radiation can be converted into electrical energy and generate electric power that can be utilized in multiple ways. The technological…”
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The emerging role of microRNAs in regulating immune and inflammatory responses in the lung by Foster, Paul S., Plank, Maximilian, Collison, Adam, Tay, Hock L., Kaiko, Gerard E., Li, JingJing, Johnston, Sebastian L., Hansbro, Philip M., Kumar, Rakesh K., Yang, Ming, Mattes, Joerg

“…Summary Chronic inflammatory diseases of the lung are leading causes of morbidity and mortality worldwide. Many of these disorders can be attributed to…”
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Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder by Kumar, Rakesh K

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Th1/17-Biased Inflammatory Environment Associated with COPD Alters the Response of Airway Epithelial Cells to Viral and Bacterial Stimuli by Herbert, Cristan, Thomas, Paul S., Kumar, Rakesh K., Chen, Yifan

“…Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation associated with a Th1/17-biased cytokine environment. Acute exacerbations…”
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Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target by Collison, Adam, Herbert, Cristan, Siegle, Jessica S, Mattes, Joerg, Foster, Paul S, Kumar, Rakesh K

“…The role of microRNAs (miRNAs) in regulating gene expression is currently an area of intense interest. Relatively little is known, however, about the role of…”
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Flexible Temperature Sensor Utilizing MWCNT Doped PEG-PU Copolymer Nanocomposites by Kumar, Amit, Hsieh, Pen-Yi, Shaikh, Muhammad Omar, Kumar, R K Rakesh, Chuang, Cheng-Hsin

“…In this study, polyethylene glycol (PEG) and polyurethane (PU)-based shape-stabilized copolymer nanocomposites were synthesized and utilized for developing…”
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Allergic environment enhances airway epithelial pro-inflammatory responses to rhinovirus infection by Herbert, Cristan, Do, Kimchi, Chiu, Vincent, Garthwaite, Linda, Chen, Yifan, Young, Paul M, Traini, Daniela, Kumar, Rakesh K

“…Airway epithelial cells (AEC) exhibit a pro-inflammatory phenotype in patients with allergic asthma. We examined the effect of an allergic cytokine environment…”
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Enhanced Pro-Inflammatory Response of Macrophages to Interleukin-33 in an Allergic Environment by Chia, Noel, Kumar, Rakesh K, Foster, Paul S, Herbert, Cristan

“…Allergic asthma is common in childhood and is associated with a T-helper type 2 (Th2)-biased immunological response. Exacerbations of asthma are characterised…”
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Universal nanocomposite coating with antifouling and redox capabilities for electrochemical affinity biosensing in complex biological fluids by Bharti, Aditya Manu, Rakesh Kumar, R K, Chuang, Cheng-Hsin, Shaikh, Muhammad Omar

“…Electrochemical affinity biosensors have the potential to facilitate the development of multiplexed point-of-care diagnostics in complex biological fluids…”
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Differential injurious effects of ambient and traffic-derived particulate matter on airway epithelial cells by Kumar, Rakesh K., Shadie, Alexander M., Bucknall, Martin P., Rutlidge, Helen, Garthwaite, Linda, Herbert, Cristan, Halliburton, Brendan, Parsons, Kristy S., Wark, Peter A.B.

“…Background and objective Exposure to airborne particulate matter (PM) may promote development of childhood asthma and trigger acute exacerbations of existing…”
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Steroid-Resistant Neutrophilic Inflammation in a Mouse Model of an Acute Exacerbation of Asthma by Ito, Kazuhiro, Herbert, Cristan, Siegle, Jessica S, Vuppusetty, Chaitanya, Hansbro, Nicole, Thomas, Paul S, Foster, Paul S, Barnes, Peter J, Kumar, Rakesh K

“…Neutrophilic inflammation in acute exacerbations of asthma tends to be resistant to treatment with glucocorticoids. This may be related to decreased activity…”
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Bacterial Endotoxin: A Trigger Factor for Alcoholic Pancreatitis? Evidence From a Novel, Physiologically Relevant Animal Model by Vonlaufen, Alain, Xu, Zhihong, Daniel, Balu, Kumar, Rakesh K, Pirola, Romano, Wilson, Jeremy, Apte, Minoti V

“…Background & Aims: This study examined the possible role of endotoxinemia (from increased gut permeability) as an additional trigger factor for overt…”
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Ym1/2 Promotes Th2 Cytokine Expression by Inhibiting 12/15(S)-Lipoxygenase: Identification of a Novel Pathway for Regulating Allergic Inflammation by Cai, Yeping, Kumar, Rakesh K, Zhou, Jiansheng, Foster, Paul S, Webb, Dianne C

“…The Ym1/2 lectin is expressed abundantly in the allergic mouse lung in an IL-13-dependent manner. However, the role of Ym1/2 in the development of allergic…”
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Adaptive Tutorials Versus Web-Based Resources in Radiology: A Mixed Methods Comparison of Efficacy and Student Engagement by Wong, Vincent, Smith, Ariella J, Hawkins, Nicholas J., MBBS, PhD, FRCPA, Kumar, Rakesh K., MBBS, PhD, FRCPA, Young, Noel, MBBS, FRANZCR, Kyaw, Merribel, MBBS, Velan, Gary M., MBBS, DipHEd, PhD

“…Rationale and Objectives Diagnostic imaging is under-represented in medical curricula globally. Adaptive tutorials, online intelligent tutoring systems that…”
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