Search Results - "KUMAMOTO, HIROYUKI"

Underlying Mechanisms and Therapeutic Strategies for Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) by Endo, Yasuo, Kumamoto, Hiroyuki, Nakamura, Masanori, Sugawara, Shunji, Takano-Yamamoto, Teruko, Sasaki, Keiichi, Takahashi, Tetsu

“…Bisphosphonates (BPs), with a non-hydrolysable P-C-P structure, are cytotoxic analogues of pyrophosphate, bind strongly to bone, are taken into osteoclasts…”
Get full text

Immunoexpression of SIRT1, 6, and 7 in oral leukoplakia and oral squamous cell carcinoma by Sripodok, Pawat, Saito, Haruka, Kouketsu, Atsumu, Takahashi, Tetsu, Kumamoto, Hiroyuki

“…[Abstract] Sirtuins (SIRTs) are a family of proteins involved in the metabolic process responsible for extending the lifespan. The role of SIRT1, 6, and 7 in…”
Get full text

Correction to : Immunoexpression of SIRT1, 6, and 7 in oral leukoplakia and oral squamous cell carcinoma by Sripodok, Pawat, Saito, Haruka, Kouketsu, Atsumu, Takahashi, Tetsu, Kumamoto, Hiroyuki

“…[Correction to : Odontology https://doi.org/10.1007/s10266-023-00816-x] In the original publication of the article, in Tables 1, 3, bold style was missing in…”
Get full text

Immunohistochemical assessment of growth factor signaling molecules : MAPK, Akt, and STAT3 pathways in oral epithelial precursor lesions and squamous cell carcinoma by Tashiro, Kazuki, Oikawa, Mariko, Miki, Yasuhiro, Takahashi, Tetsu, Kumamoto, Hiroyuki

“…[Abstract] Several growth factors and their receptors, such as epidermal growth factor receptor, have been studied as prognostic biomarkers for many epithelial…”
Get full text

Myeloid‐derived suppressor cells and plasmacytoid dendritic cells are associated with oncogenesis of oral squamous cell carcinoma by Kouketsu, Atsumu, Haruka, Saito, Kuroda, Kanako, Hitoshi, Miyashita, Kensuke, Yamauchi, Tsuyoshi, Sugiura, Takahashi, Tetsu, Hiroyuki, Kumamoto

“…Myeloid‐derived suppressor cells (MDSCs) help establish the tumor microenvironment by suppressing T‐cell response in tumor‐bearing hosts. Plasmacytoid…”
Get full text

Osteogenic response under the periosteum by magnesium implantation in rat tibia by ODASHIMA, Kenji, SHIMIZU, Yoshinaka, SANO, Yuya, YAMAMOTO, Akiko, MUKAI, Toshiji, TAKADA, Yukyo, YANAGISAWA, Yuta, IMAI, Yoshimichi, TAKAHASHI, Tetsu, KUMAMOTO, Hiroyuki

“…This study was designed to examine osteoconductive effects of Mg in rats tibia. The animals were sacrificed after 1, 2, and 8 weeks. The elemental analysis was…”
Get full text

In vitro and in vivo analysis of the biodegradable behavior of a magnesium alloy for biomedical applications by SATO, Takumi, SHIMIZU, Yoshinaka, ODASHIMA, Kenji, SANO, Yuya, YAMAMOTO, Akiko, MUKAI, Toshiji, IKEO, Naoko, TAKAHASHI, Tetsu, KUMAMOTO, Hiroyuki

“…The present study was designed to investigate the biodegradation behavior of Mg alloy plates in the maxillofacial region. For in vitro analysis, the plates…”
Get full text

Expression of immunoregulatory molecules PD-L1 and PD-1 in oral cancer and precancerous lesions: A cohort study of Japanese patients by Kouketsu, Atsumu, DDS, Sato, Ikuro, MD, PhD, Oikawa, Mariko, PhD, Shimizu, Yoshinaka, PhD, Saito, Hiroki, DDS, Takahashi, Tetsu, DDS, PhD, Kumamoto, Hiroyuki, PhD

“…Abstract Objective An association of the programmed cell death-1 (PD-1) and its ligand PD-L1 with various types of malignant tumors has been established. This…”
Get full text

In vivo behavior of untreated and compressed concentrated growth factors as biomaterials in rabbits by TONE, Takeshi, SHIMIZU, Yoshinaka, SAITO, Haruka, SATO, Takumi, ITO, Hidetoshi, TAKADA, Yukyo, TAKAHASHI, Masatoshi, ODASHIMA, Kenji, OIKAWA, Mariko, TAKAHASHI, Tetsu, KUMAMOTO, Hiroyuki

“…To characterize concentrated growth factors (CGFs) in vivo, we examined the degradation of implanted CGF in rabbits. Untreated CGF (U-CGF) and compressed CGF…”
Get full text

Immunohistochemical assessment of Eph/ephrin expression in oral squamous cell carcinoma and precursor lesions by Saito, Hiroki, Oikawa, Mariko, Kouketsu, Atsumu, Takahashi, Tetsu, Kumamoto, Hiroyuki

“…[Abstract] To evaluate erythropoietin-producing hepatocellular carcinoma (Eph)/Eph receptor-interaction protein (ephrin) expression in oral squamous cell…”
Get full text

Comparison of different diagnostic imaging techniques for the detection of bone invasion in oral cancers by Kouketsu, Atsumu, Miyashita, Hitoshi, Kojima, Ikuho, Sakamoto, Maya, Murata, Takaki, Mori, Shiro, Nogami, Shinnnosuke, Yamauchi, Kensuke, Nagai, Hirokazu, Kumamoto, Hiroyuki, Takahashi, Tetsu

“…•Magnetic resonance imaging—most reliably detects bone invasion in oral cancers.•A negative MRI result definitively excludes bone marrow invasion.•In positive…”
Get full text

Roles of Aryl Hydrocarbon Receptor in Aromatase-Dependent Cell Proliferation in Human Osteoblasts by Miki, Yasuhiro, Hata, Shuko, Ono, Katsuhiko, Suzuki, Takashi, Ito, Kiyoshi, Kumamoto, Hiroyuki, Sasano, Hironobu

“…Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and its expression is influenced by environmental compounds, such as…”
Get full text

Mandibular osteomyelitis showing remarkable bone resorption in association with Entamoeba gingivalis infection: Report of two cases by Kurobane, Tsuyoshi, Mori, Shiro, Miyashita, Hitoshi, Kumamoto, Hiroyuki, Takahashi, Tetsu

“…Entamoeba gingivalis is thought to be parasitic in the periodontal pocket. However, its behavior as an infectious organism in the oral region is still not well…”
Get full text

In vivo behaviors of highly flexible paper consisting of ultralong hydroxyapatite nanowires by Kashiwada, Hajime, Shimizu, Yoshinaka, Sano, Yuya, Yamauchi, Kensuke, Guang, Hong, Kumamoto, Hiroyuki, Unuma, Hidero, Zhu, Ying‐Jie

“…This study was conducted in order to investigate biological compatibility of a thin and flexible hydroxyapatite (HAP) paper which consists of ultralong…”
Get full text

Detection of human papillomavirus infection in oral squamous cell carcinoma: a cohort study of Japanese patients by Kouketsu, Atsumu, Sato, Ikuro, Abe, Satoko, Oikawa, Mariko, Shimizu, Yoshinaka, Takahashi, Tetsu, Kumamoto, Hiroyuki

“…Objective Recent evidence suggests that human papillomavirus (HPV)‐related head and neck squamous cell carcinoma (HNSCC) is a separate HNSCC subgroup with…”
Get full text

Peripheral clear cell variant of calcifying epithelial odontogenic tumor devoid of calcification by Kurihara, Jun, Mori, Shiro, Oikawa, Mariko, Kumamoto, Hiroyuki, Takahashi, Tetsu

“…A clear cell variant of calcifying epithelial odontogenic tumor (CCEOT) affecting an extraosseous site is described. A 60-year-old male patient presented with…”
Get full text

Induction of the Histamine-Forming Enzyme Histidine Decarboxylase in Skeletal Muscles by Prolonged Muscular Work: Histological Demonstration and Mediation by Cytokines by Ayada, Kentaro, Tsuchiya, Masahiro, Yoneda, Hiroyuki, Yamaguchi, Kouji, Kumamoto, Hiroyuki, Sasaki, Keiichi, Tadano, Takeshi, Watanabe, Makoto, Endo, Yasuo

“…Recent studies suggest that histamine—a regulator of the microcirculation—may play important roles in exercise. We have shown that the histamine-forming enzyme…”
Get full text

Condylar Resorption Following Compressive Mechanical Stress in Rabbit Model - Association of Matrix Metalloproteinases by NOGAMI, SHINNOSUKE, KATAOKA, YOSHIHIRO, YAMAUCHI, KENSUKE, YANAGISAWA, YUTA, IMOTO, KAZUHIRO, KUMASAKA, AKIRA, IZUMITA, KUNIYUKI, KAJITA, TOMONARI, IIKUBO, MASAHIRO, KUMAMOTO, HIROYUKI, TAKAHASHI, TETSU

“…BACKGROUND/AIMIdiopathic condylar resorption (ICR) is a morphological change of the condylar head that occurs following orthodontic treatment or orthognathic…”
Get full text

Guanine nucleotide‐binding protein 1 is one of the key molecules contributing to cancer cell radioresistance by Fukumoto, Motoi, Amanuma, Tatsuya, Kuwahara, Yoshikazu, Shimura, Tsutomu, Suzuki, Masatoshi, Mori, Shiro, Kumamoto, Hiroyuki, Saito, Yohei, Ohkubo, Yasuhito, Duan, Zhenfeng, Sano, Kenji, Oguchi, Tomohiro, Kainuma, Kazuyuki, Usami, Shinichi, Kinoshita, Kengo, Lee, Inchul, Fukumoto, Manabu

“…Standard fractionated radiotherapy for the treatment of cancer consists of daily irradiation of 2‐Gy X‐rays, 5 days a week for 5–8 weeks. To understand the…”
Get full text

Biodegradation behaviors of magnesium(Mg)-based alloy nails in autologous bone grafts: In vivo study in rabbit skulls by Yanagisawa, Yuta, Shimizu, Yoshinaka, Mukai, Toshiji, Sano, Yuya, Odashima, Kenji, Ikeo, Naoko, Saito, Haruka, Yamauchi, Kensuke, Takahashi, Tetsu, Kumamoto, Hiroyuki

“…Objective: In this study, autologous bone grafts using bone-fixing nails made of magnesium-zinc-calcium ternary alloys were performed using rabbit skulls…”
Get full text