Search Results - "KUMAGAI, Jin"

Brain-Derived Neurotrophic Factor Promotes Implantation and Subsequent Placental Development by Stimulating Trophoblast Cell Growth and Survival by Kawamura, Kazuhiro, Kawamura, Nanami, Sato, Wataru, Fukuda, Jun, Kumagai, Jin, Tanaka, Toshinobu

“…Successful implantation of the blastocyst and subsequent placental development is essential for reproduction. Expression of brain-derived neurotrophic factor…”
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Isolated Loss of PMS2 Immunohistochemical Expression is Frequently Caused by Heterogenous MLH1 Promoter Hypermethylation in Lynch Syndrome Screening for Endometrial Cancer Patients by Kato, Aya, Sato, Naoki, Sugawara, Tae, Takahashi, Kazue, Kito, Masahiko, Makino, Kenichi, Sato, Toshiharu, Shimizu, Dai, Shirasawa, Hiromistu, Miura, Hiroshi, Sato, Wataru, Kumazawa, Yukiyo, Sato, Akira, Kumagai, Jin, Terada, Yukihiro

“…Lynch syndrome (LS) is an autosomal-dominant inherited disorder mainly caused by a germline mutation in the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6,…”
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Immune Cell-Epithelial/Mesenchymal Interaction Contributing to Allergic Airway Inflammation Associated Pathology by Hirahara, Kiyoshi, Shinoda, Kenta, Morimoto, Yuki, Kiuchi, Masahiro, Aoki, Ami, Kumagai, Jin, Kokubo, Kota, Nakayama, Toshinori

“…The primary function of the lung is efficient gas exchange between alveolar air and alveolar capillary blood. At the same time, the lung protects the host from…”
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Development of a new clinically applicable device for embryo evaluation which measures embryo oxygen consumption by Kurosawa, Hiroki, Utsunomiya, Hiroki, Shiga, Naomi, Takahashi, Aiko, Ihara, Motomasa, Ishibashi, Masumi, Nishimoto, Mitsuo, Watanabe, Zen, Abe, Hiroyuki, Kumagai, Jin, Terada, Yukihiro, Igarashi, Hideki, Takahashi, Toshifumi, Fukui, Atsushi, Suganuma, Ryota, Tachibana, Masahito, Yaegashi, Nobuo

“…Abstract STUDY QUESTION Does a new system—the chip-sensing embryo respiration monitoring system (CERMs)—enable evaluation of embryo viability for potential…”
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Memory-type ST2+CD4+ T cells participate in the steroid-resistant pathology of eosinophilic pneumonia by Mato, Naoko, Hirahara, Kiyoshi, Ichikawa, Tomomi, Kumagai, Jin, Nakayama, Masayuki, Yamasawa, Hideaki, Bando, Masashi, Hagiwara, Koichi, Sugiyama, Yukihiko, Nakayama, Toshinori

“…The lung develops an unique epithelial barrier system to protect host from continuous invasion of various harmful particles. Interleukin (IL-)33 released from…”
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CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet by Kurita, Kenichi, Ishikawa, Ko, Takeda, Kenji, Fujimoto, Masanori, Ono, Hiraku, Kumagai, Jin, Inoue, Hiromi, Yokoh, Hidetaka, Yokote, Koutaro

“…Brown adipose tissue (BAT) plays a role in energy expenditure and is involved in nutrient metabolism. C-X-C chemokine ligand 12 (CXCL12)-CXCR4 pathway…”
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Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling Regulates Human Trophoblast Growth in an in Vivo Animal Model of Ectopic Pregnancy by Kawamura, Kazuhiro, Kawamura, Nanami, Kumazawa, Yukiyo, Kumagai, Jin, Fujimoto, Toshio, Tanaka, Toshinobu

“…Paracrine signaling of the BDNF/TrkB system is important for human trophoblast growth, and its inhibition could provide medical treatment for ectopic…”
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Activation of Orphan Receptors by the Hormone Relaxin by Hsu, Sheau Yu, Nakabayashi, Koji, Nishi, Shinya, Kumagai, Jin, Kudo, Masataka, Sherwood, O. David, Aaron J. W. Hsueh

“…Relaxin is a hormone important for the growth and remodeling of reproductive and other tissues during pregnancy. Although binding sites for relaxin are widely…”
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Central administration of sodium-glucose cotransporter-2 inhibitors increases food intake involving adenosine monophosphate-activated protein kinase phosphorylation in the lateral hypothalamus in healthy rats by Takeda, Kenji, Ono, Hiraku, Ishikawa, Ko, Ohno, Tomohiro, Kumagai, Jin, Ochiai, Hidetoshi, Matumoto, Ai, Yokoh, Hidetaka, Maezawa, Yoshiro, Yokote, Koutaro

“…IntroductionSodium glucose cotransporter-2 (SGLT2) inhibitors are widely used for diabetes treatment. Although SGLT2 inhibitors have been clinically observed…”
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An optimized protocol for the analysis of house dust mite (Dermatophagoides farinae)-induced neutrophil-dominant airway inflammation by Wada, Tomoko, Hirahara, Kiyoshi, Aoki, Ami, Morimoto, Yuki, Kiuchi, Masahiro, Kumagai, Jin, Okano, Mikiko, Kokubo, Kota, Kato, Miki, Fukano, Chiharu, Ohashi-Doi, Katsuyo, Nakayama, Toshinori

“…House dust mites (HDMs), Dermatophagoides sp., are one of the most widespread aeroallergens worldwide and cause various allergic diseases, including asthma…”
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Regulation of preimplantation embryo development by brain-derived neurotrophic factor by Kawamura, Kazuhiro, Kawamura, Nanami, Fukuda, Jun, Kumagai, Jin, Hsueh, Aaron J.W., Tanaka, Toshinobu

“…Hormonal factors secreted by embryos and reproductive tracts are important for successful development of preimplantation embryos. We found expression of…”
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Paracrine Regulation of Mammalian Oocyte Maturation and Male Germ Cell Survival by Kawamura, Kazuhiro, Kumagai, Jin, Sudo, Satoko, Chun, Sang-Young, Pisarska, Margareta, Morita, Hiroki, Toppari, Jorma, Fu, Ping, Wade, John D., Ross A. D. Bathgate, Aaron J. W. Hsueh, Vale, Wylie

“…Mammalian oocytes are arrested at the prophase of meiosis before induction of maturation by the preovulatory luteinizing hormone (LH) surge. LH also promotes…”
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Novel method for immunofluorescence staining of mammalian eggs using non-contact alternating-current electric-field mixing of microdroplets by Shirasawa, Hiromitsu, Kumagai, Jin, Sato, Emiko, Kabashima, Katsuya, Kumazawa, Yukiyo, Sato, Wataru, Miura, Hiroshi, Nakamura, Ryuta, Nanjo, Hiroshi, Minamiya, Yoshihiro, Akagami, Yoichi, Terada, Yukihiro

“…Recently, a new technique was developed for non-catalytically mixing microdroplets. In this method, an alternating-current (AC) electric field is used to…”
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H3 Relaxin Is a Specific Ligand for LGR7 and Activates the Receptor by Interacting with Both the Ectodomain and the Exoloop 2 by Sudo, Satoko, Kumagai, Jin, Nishi, Shinya, Layfield, Sharon, Ferraro, Tania, Bathgate, Ross A D, Hsueh, Aaron J W

“…Leucine-rich repeat-containing, G protein-coupled receptors (LGRs) represent a unique subgroup of G protein-coupled receptors with a large ectodomain. Recent…”
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Time-lapse monitoring reveals that vitrification increases the frequency of contraction during the pre-hatching stage in mouse embryos by SHIMODA, Yuki, KUMAGAI, Jin, ANZAI, Mibuki, KABASHIMA, Katsuya, TOGASHI, Kazue, MIURA, Yasuko, SHIRASAWA, Hiromitsu, SATO, Wataru, KUMAZAWA, Yukiyo, TERADA, Yukihiro

“…Contraction during the blastocyst stage is observed during embryonic development of various mammals, including humans, but the physiological role of this…”
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Dysfunction in gap junction intercellular communication induces aberrant behavior of the inner cell mass and frequent collapses of expanded blastocysts in mouse embryos by Togashi, Kazue, Kumagai, Jin, Sato, Emiko, Shirasawa, Hiromitsu, Shimoda, Yuki, Makino, Kenichi, Sato, Wataru, Kumazawa, Yukiyo, Omori, Yasufumi, Terada, Yukihiro

“…Purpose We investigated the role of gap junctions (GJs) in embryological differentiation, and observed the morphological behavior of the inner cell mass (ICM)…”
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Suppression of Hydatidiform Molar Growth by Inhibiting Endogenous Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling by Kawamura, Kazuhiro, Kawamura, Nanami, Kawagoe, Yuta, Kumagai, Jin, Fujimoto, Toshio, Terada, Yukihiro

“…Brain-derived neurotrophic factor (BDNF)/tyrosine kinase B (TrkB) receptor signaling promotes trophoblast growth in normal and abnormal pregnancy. It also…”
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Retrieval and in vitro maturation of human oocytes from ovaries removed during surgery for endometrial carcinoma: a novel strategy for human oocyte research by Shirasawa, Hiromitsu, Kumagai, Jin, Sato, Wataru, Kumazawa, Yukiyo, Sato, Naoki, Terada, Yukihiro

“…Purpose To collect human oocytes from ovaries removed as part of surgical treatment for endometrial carcinoma, and to induce in vitro maturation of such…”
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CRP 1846C>T Genetic Polymorphism Is Associated with Lymph Node Metastasis and/or Severe Lymphatic Invasion in Endometrial Cancer by Kito, Masahiko, Motoyama, Satoru, Fujita, Kazuma, Miura, Masatomo, Nanjo, Hiroshi, Sato, Naoki, Shimizu, Dai, Sato, Toshiharu, Makino, Kenichi, Sugawara, Tae, Kato, Aya, Tamura, Daisuke, Takahashi, Kazue, Kumazawa, Yukiyo, Sato, Wataru, Miura, Hiroshi, Shirasawa, Hiromitsu, Sato, Akira, Kumagai, Jin, Terada, Yukihiro

“…Endometrial cancer (EC) rates are rising in Japan. Lymph node (LN) metastasis is an important prognostic factor in EC, and its risk is increased with higher…”
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Acute Myelogenous Leukemia with Leptotrichia trevisanii Bacteremia by Kumagai, Jin, Takiguchi, Yasuo, Shono, Katsuhiro, Suruga, Yosuke, Akiba, Yoko, Yamamoto, Kyohei, Terano, Takashi

“…A 74-year-old woman visited an otolaryngology clinic with pharyngeal pain, and was diagnosed with a peritonsillar abscess. She received antibiotics and…”
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