Search Results - "KULLMANN, STEPHANIE"
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Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans
Published in Physiological reviews (01-10-2016)“…Ever since the brain was identified as an insulin-sensitive organ, evidence has rapidly accumulated that insulin action in the brain produces multiple…”
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Impaired insulin action in the human brain: causes and metabolic consequences
Published in Nature reviews. Endocrinology (01-12-2015)“…Key Points The human brain is an insulin-sensitive organ Insulin in the human brain modulates food intake, body weight and peripheral metabolism The human…”
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Brain insulin sensitivity is linked to adiposity and body fat distribution
Published in Nature communications (15-04-2020)“…Brain insulin action regulates eating behavior and energy fluxes throughout the body. However, numerous people are brain insulin resistant. How brain insulin…”
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Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults
Published in Diabetes care (01-06-2015)“…Impaired brain insulin action has been linked to obesity, type 2 diabetes, and neurodegenerative diseases. To date, the central nervous effects of insulin in…”
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Food related processes in the insular cortex
Published in Frontiers in human neuroscience (23-08-2013)“…The insular cortex is a multimodal brain region with regional cytoarchitectonic differences indicating various functional specializations. As a multisensory…”
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Processing of food pictures: Influence of hunger, gender and calorie content
Published in Brain research (02-09-2010)“…Abstract In most cases obesity, a major risk factor for diabetes mellitus type 2 and other associated chronic diseases, is generated by excessive eating. For a…”
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Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men
Published in Diabetes (New York, N.Y.) (01-12-2014)“…Animal studies suggest that insulin action in the brain is involved in the regulation of peripheral insulin sensitivity. Whether this holds true in humans is…”
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Safety of intranasal human insulin: A review
Published in Diabetes, obesity & metabolism (01-07-2018)“…Aims To conduct a review in order to assess the safety of intranasal human insulin in clinical studies as well as the temporal stability of nasal insulin…”
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Resting-state functional connectivity of the human hypothalamus
Published in Human brain mapping (01-12-2014)“…The hypothalamus is of enormous importance for multiple bodily functions such as energy homeostasis. Especially, rodent studies have greatly contributed to our…”
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Dose-Dependent Effects of Intranasal Insulin on Resting-State Brain Activity
Published in The journal of clinical endocrinology and metabolism (01-01-2018)“…Insulin action in the human brain influences eating behavior, cognition, and whole-body metabolism. Studies investigating brain insulin rely on intranasal…”
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Intranasal insulin enhances brain functional connectivity mediating the relationship between adiposity and subjective feeling of hunger
Published in Scientific reports (09-05-2017)“…Brain insulin sensitivity is an important link between metabolism and cognitive dysfunction. Intranasal insulin is a promising tool to investigate central…”
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Network-targeted transcranial direct current stimulation of the hypothalamus appetite-control network: a feasibility study
Published in Scientific reports (18-05-2024)“…The hypothalamus is the key regulator for energy homeostasis and is functionally connected to striatal and cortical regions vital for the inhibitory control of…”
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Functional network connectivity underlying food processing: disturbed salience and visual processing in overweight and obese adults
Published in Cerebral cortex (New York, N.Y. 1991) (01-05-2013)“…In order to adequately explore the neurobiological basis of eating behavior of humans and their changes with body weight, interactions between brain areas or…”
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Differential effect of glucose ingestion on the neural processing of food stimuli in lean and overweight adults
Published in Human brain mapping (01-03-2014)“…Eating behavior is crucial in the development of obesity and Type 2 diabetes. To further investigate its regulation, we studied the effects of glucose versus…”
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Diminished prefrontal cortex activation in patients with binge eating disorder associates with trait impulsivity and improves after impulsivity-focused treatment based on a randomized controlled IMPULS trial
Published in NeuroImage clinical (01-01-2021)“…•Persons with binge eating disorder show increased impulsivity.•We investigated cognitive control to food cues using fNIRS.•Compared to healthy controls, binge…”
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Network targeted brain stimulation improves task performance in participants with overweight and obesity
Published in Brain stimulation (01-01-2023)Get full text
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Reduced cortical thickness associated with visceral fat and BMI
Published in NeuroImage clinical (01-01-2014)“…Structural brain imaging studies have shown that obesity is associated with widespread reductions in gray matter (GM) volume. Although the body mass index…”
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Insulin sensitivity predicts cognitive decline in individuals with prediabetes
Published in BMJ open diabetes research & care (17-11-2020)“…IntroductionEpidemiological studies indicate an association between type 2 diabetes and cognitive dysfunction that appear to start already in the prediabetic…”
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No modulation of postprandial metabolism by transcutaneous auricular vagus nerve stimulation: a cross-over study in 15 healthy men
Published in Scientific reports (24-11-2020)“…Experimental evidence suggests a crucial role of the autonomic nervous system in whole body metabolism with major regulatory effects of the parasympathetic…”
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Slow deep breathing modulates cardiac vagal activity but does not affect peripheral glucose metabolism in healthy men
Published in Scientific reports (13-10-2021)“…Parasympathetic nervous system innervates peripheral organs including pancreas, hepatic portal system, and gastrointestinal tract. It thereby contributes to…”
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