Search Results - "KULKARNI, A. B"

STAT3 Induces Immunosuppression by Upregulating PD-1/PD-L1 in HNSCC by Bu, L.L., Yu, G.T., Wu, L., Mao, L., Deng, W.W., Liu, J.F., Kulkarni, A.B., Zhang, W.F., Zhang, L., Sun, Z.J.

“…Head and neck cancer is one of the most prevalent cancers around the world. Head and neck squamous cell carcinoma (HNSCC) accounts for nearly 90% of head and…”
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Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma by Zhang, L, Zhang, W, Wang, Y-F, Liu, B, Zhang, W-F, Zhao, Y-F, Kulkarni, A B, Sun, Z-J

“…Survivin is ubiquitously expressed in patients with head neck squamous cell carcinoma (HNSCC) and is associated with poor survival and chemotherapy resistance…”
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Targeted TNF-α Overexpression Drives Salivary Gland Inflammation by Limaye, A., Hall, B.E., Zhang, L., Cho, A., Prochazkova, M., Zheng, C., Walker, M., Adewusi, F., Burbelo, P.D., Sun, Z.J., Ambudkar, I.S., Dolan, J.C., Schmidt, B.L., Kulkarni, A.B.

“…Chronic inflammation of the salivary glands from pathologic conditions such as Sjögren’s syndrome can result in glandular destruction and hyposalivation. To…”
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Conditional TNF-α Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis by Hall, B.E., Zhang, L., Sun, Z.J., Utreras, E., Prochazkova, M., Cho, A., Terse, A., Arany, P., Dolan, J.C., Schmidt, B.L., Kulkarni, A.B.

“…Tumor necrosis factor–α (TNF-α) is a proalgesic cytokine that is commonly expressed following tissue injury. TNF-α expression not only promotes inflammation…”
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Synergistic Roles of Amelogenin and Ameloblastin by Hatakeyama, J., Fukumoto, S., Nakamura, T., Haruyama, N., Suzuki, S., Hatakeyama, Y., Shum, L., Gibson, C. W., Yamada, Y., Kulkarni, A. B.

“…Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel…”
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Gene Expression Patterns of Murine Dentin Matrix Protein 1 (Dmp1) and Dentin Sialophosphoprotein (DSPP) Suggest Distinct Developmental Functions In Vivo by D'souza, R. N., Cavender, A., Sunavala, G., Alvarez, J., Ohshima, T., Kulkarni, A. B., MacDougall, M.

“…Although the precise mechanisms of the conversion of predentin to dentin are not well understood, several lines of evidence implicate the noncollagenous…”
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The Amelogenin C-Terminus Is Required for Enamel Development by Pugach, M.K., Li, Y., Suggs, C., Wright, J.T., Aragon, M.A., Yuan, Z.A., Simmons, D., Kulkarni, A.B., Gibson, C.W.

“…The abundant amelogenin proteins are responsible for generating proper enamel thickness and structure, and most amelogenins include a conserved hydrophilic…”
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Cyclin-dependent kinase 5 is required for normal cerebellar development by Kumazawa, A., Mita, N., Hirasawa, M., Adachi, T., Suzuki, H., Shafeghat, N., Kulkarni, A.B., Mikoshiba, K., Inoue, T., Ohshima, T.

“…Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase, and its kinase activity is dependent upon its association with either of the activating subunits…”
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M180 Amelogenin Processed by MMP20 is Sufficient for Decussating Murine Enamel by Pugach, M.K., Suggs, C., Li, Y., Wright, J.T., Kulkarni, A.B., Bartlett, J.D., Gibson, C.W.

“…Amelogenin (AMELX) and matrix metalloproteinase-20 (MMP20) are essential for proper enamel development. Amelx and Mmp20 mutations cause amelogenesis…”
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Expression and Function of Enamel-related Gene Products in Calvarial Development by Atsawasuwan, P., Lu, X., Ito, Y., Chen, Y., Gopinathan, G., Evans, C.A., Kulkarni, A.B., Gibson, C.W., Luan, X., Diekwisch, T.G.H.

“…Enamel-related gene products (ERPs) are detected in non-enamel tissues such as bone. We hypothesized that, if functional, ERP expression corresponds with…”
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The Use of Mouse Models to Investigate Shear Bond Strength in Amelogenesis Imperfecta by Pugach, M.K., Ozer, F., Li, Y., Sheth, K., Beasley, R., Resnick, A., Daneshmehr, L., Kulkarni, A.B., Bartlett, J.D., Gibson, C.W., Lindemeyer, R.G.

“…Patients with amelogenesis imperfecta (AI) have defective enamel; therefore, bonded restorations of patients with AI have variable success rates. To…”
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Transgenic Mice that Express Normal and Mutated Amelogenins by Gibson, C.W., Yuan, Z.A., Li, Y., Daly, B., Suggs, C., Aragon, M.A., Alawi, F., Kulkarni, A.B., Wright, J.T.

“…Amelogenin proteins are secreted by ameloblasts within the enamel organ during tooth development. To better understand the function of the 180-amino-acid…”
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Synthesis, characterization and low frequency a.c. conduction of polyaniline/fly ash composites by Raghavendra, S. C., Khasim, Syed, Revanasiddappa, M., Ambika Prasad, M. V. N., Kulkarni, A. B.

“…In situ polymerization of aniline was carried out in the presence of fly ash (FA) to synthesize polyaniline/ fly ash (PANI/FA) composites. The PANI/FA…”
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Targeted Disruption of the Cyclin-Dependent Kinase 5 Gene Results in Abnormal Corticogenesis, Neuronal Pathology and Perinatal Death by Ohshima, Toshio, Ward, Jerrold M., Huh, Chang-Goo, Longenecker, Glenn, Veeranna, Pant, Harish C., Brady, Roscoe O., Martin, Lee J., Kulkarni, Ashok B.

“…Although cyclin-dependent kinase 5 (Cdk5) is closely related to other cyclin-dependent kinases, its kinase activity is detected only in the postmitotic…”
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Synthesis and Structural Analysis of Co–Zn–Cd Ferrite by Williamson–Hall and Size–Strain Plot Methods by Kulkarni, A. B., Mathad, S. N.

“…The work aimed at studying the structural properties of Cd-doped cobalt zinc ferrite (Co 0.5 Zn 0.5 Cd 0.2 Fe 1.8 O 4 ) prepared by simple, low-cost…”
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Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice by Young, Marian F, Xu, Tianshun, Bianco, Paolo, Fisher, Larry W, Longenecker, Glenn, Smith, Erica, Goldstein, Steven, Bonadio, Jeffrey, Boskey, Adele, Heegaard, Anne-Marie, Sommer, Beatrice, Satomura, Kazuhito, Dominguez, Pedro, Zhao, Chengyan, Kulkarni, Ashok B, Robey, Pamela Gehron

“…The resilience and strength of bone is due to the orderly mineralization of a specialized extracellular matrix (ECM) composed of type I collagen (90%) and a…”
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Severe endothelial dysfunction in the aorta of a mouse model of Fabry disease; partial prevention by N‐butyldeoxynojirimycin treatment by Heare, T., Alp, N. J., Priestman, D. A., Kulkarni, A. B., Qasba, P., Butters, T. D., Dwek, R. A., Clarke, K., Channon, K. M., Platt, F. M.

“…Summary Objective: Fabry disease results from α‐gala‐ ctosidase A deficiency and is characterized by the lysosomal accumulation of globotriaosylceramide…”
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Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation by Bian, Y, Hall, B, Sun, Z-J, Molinolo, A, Chen, W, Gutkind, J S, Waes, C V, Kulkarni, A B

“…The molecular mechanisms that contribute to the initiation and progression of head and neck squamous cell carcinoma (HNSCC) have not been completely…”
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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death by Kulkarni, A B, Huh, C G, Becker, D, Geiser, A, Lyght, M, Flanders, K C, Roberts, A B, Sporn, M B, Ward, J M, Karlsson, S

“…To delineate specific developmental roles of transforming growth factor beta 1 (TGF-beta 1) we have disrupted its cognate gene in mouse embryonic stem cells by…”
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Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease by Kulkarni, A B, Karlsson, S

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