Search Results - "KULAWY, R"

Effect of administration of moxifloxacin plus rifampin against Mycobacterium tuberculosis for 7 of 7 days versus 5 of 7 days in an in vitro pharmacodynamic system by Drusano, G L, Sgambati, N, Eichas, A, Brown, D, Kulawy, R, Louie, A

“…Some trials administered antituberculosis agents for 5 of 7 days (5/7-day regimen) to optimize adherence. Since moxifloxacin has a longer half-life than…”
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Impact of Spore Biology on the Rate of Kill and Suppression of Resistance in Bacillus anthracis by DRUSANO, G. L, OKUSANYA, O. O, LOUIE, A, OKUSANYA, A. O, VAN SOY, B, BROWN, D. L, FREGEAU, C, KULAWY, R, KINZIG, M, SÖRGEL, F, HEINE, H. S

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam by Kashuba, Angela D.M., Bertino, Joseph S., Rocci, Mario L., Kulawy, Robert W., Beck, Debra J., Nafziger, Anne N.

“…Objective Intraindividual variability and the effects of sex and menstrual cycle phase on CYP3A activity were evaluated by phenotyping with use of midazolam as…”
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Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping by Kashuba, Angela D.M., Nafziger, Anne N., Kearns, Gregory L., Leeder, J. Steven, Gotschall, Russell, Rocci, Mario L., Kulawy, Robert W., Beck, Debra J., Bertino, Joseph S.

“…Objective To determine the effect of 150 mg/day fluvoxamine on the activities of CYP1A2, CYP2D6, CYP3A, N‐acetyltransferase‐2 (NAT2), and xanthine oxidase (XO)…”
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Over-the-Counter Progesterone Cream Produces Significant Drug Exposure Compared to a Food and Drug Administration-Approved Oral Progesterone Product by Hermann, Anne C., Nafziger, Anne N., Victory, Jennifer, Kulawy, Robert, Rocci Jr, Mario L., Bertino Jr, Joseph S.

“…Progesterone products are available in prescription form as well as over‐the‐counter (OTC) topical preparations sold for “cosmetic” uses. In a randomized study…”
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Optimal Plasma Sampling to Predict AUC of The CYP3A Probe Midazolam (MID) by Kim, J.S., Kashuba, A.D.M., Nafziger, A.N., Rocci, M.L., Kulawy, R.W., Beck, D.J., Bertino, J.S.

“…Clinical Pharmacology & Therapeutics (1999) 65, 185–185; doi:…”
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Dextromethorphan (DM) N-Demethylation (N-D) Does Not Accurately Reflect Hepatic CYP3A Phenotype by Kashuba, A.D.M., Nafziger, A.N., Kearns, G.L., Leeder, J.S., Gotschall, R., Rocci, M.L., Kulawy, R.W., Beck, D.J., Bertino, J.S.

“…Clinical Pharmacology & Therapeutics (1999) 65, 170–170; doi:…”
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Effect of Administration of Moxifloxacin plus Rifampin against Mycobacterium tuberculosis for 7 of 7 Days versus 5 of 7 Days in an italic toggle="yes">In Vitro /italic> Pharmacodynamic System by G. L. Drusano, N. Sgambati, A. Eichas, D. Brown, R. Kulawy, A. Louie

“…ABSTRACT Some trials administered antituberculosis agents for 5 of 7 days (5/7-day regimen) to optimize adherence. Since moxifloxacin has a longer half-life…”
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Use of midazolam urinary metabolic ratios for cytochrome P450 3A (CYP3A) phenotyping by STREETMAN, Daniel S, KASHUBA, Angela D. M, BERTINO, Joseph S, KULAWY, Robert, ROCCI, Mario L, NAFZIGER, Anne N

“…Midazolam (MDZ) total clearance (ClT) is widely used for cytochrome P450 3A (CYP3A) phenotyping, but requires up to eight blood samples. This study was…”
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Bioequivalence of over-the-counter (OTC) progesterone cream (PC) by Hermann, A. C., Nafziger, A. N., Victory, J., Rocci, M. L., Kulawy, R., Bertino, J. S.

“…Progesterone cream is an OTC (non‐prescription) product that contains USP Progesterone (P). The exposure (E) of progesterone cream (PC) was compared to an FDA…”
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Limited Sampling Strategy to Predict AUC of the CYP3A Phenotyping Probe Midazolam in Adults: Application to Various Assay Techniques by Kim, Jooran S, Nafziger, Anne N, Tsunoda, Shirley M, Choo, Edna F, Streetman, Daniel S, Kashuba, Angela D. M, Kulawy, Robert W, Beck, Debra J, Rocci, Mario L, Wilkinson, Grant R, Greenblatt, David J, Bertino, Joseph S

“…Midazolam clearance is used to phenotype hepatic CYP3A activity but requires multiple plasma samples following a single intravenous dose. The authors evaluated…”
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