Search Results - "KULAS, D. T"

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226 by Freund, GG, Kulas, DT, Mooney, RA

“…Insulin receptors and insulin-like growth factor-1 (IGF-1) receptors are present in circulating human B lymphocytes (B cells) and certain B cell malignancies,…”
Get full text

The Transmembrane Protein-tyrosine Phosphatase LAR Modulates Signaling by Multiple Receptor Tyrosine Kinases (∗) by Kulas, Donald T., Goldstein, Barry J., Mooney, Robert A.

“…Antisense-mediated suppression of the transmembrane protein-tyrosine phosphatase (PTPase) LAR has been shown previously to increase insulin-dependent…”
Get full text

Insulin Receptor Signaling Is Augmented by Antisense Inhibition of the Protein Tyrosine Phosphatase LAR (∗) by Kulas, Donald T., Zhang, Wei-Ren, Goldstein, Barry J., Furlanetto, Richard W., Mooney, Robert A.

“…Considerable evidence has shown that most physiologic responses to insulin require activation of the intrinsic tyrosine kinase of the insulin receptor…”
Get full text

Juvenile idiopathic arthritis by Kulas, Donald T, Schanberg, Laura

“…A significant amount of work has been performed over the past 2 years further defining the pathophysiology of juvenile idiopathic arthritis (JIA). The…”
Get full text

Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines by FREUND, G. G, KULAS, D. T, WAY, B. A, MOONEY, R. A

“…While IGF-1 plays a role in early B-cell development, little is known of insulin and insulin-like growth factor-1 (IGF-1) action in post-marrow B-cells…”
Get full text

The Protein Tyrosine Phosphatase LAR Has a Major Impact on Insulin Receptor Dephosphorylation by Mooney, Robert A., Kulas, Donald T., Bleyle, Lisa A., Novak, John S.

“…Transmembrane protein tyrosine phosphatases (PTPases) may act as regulators of the insulin receptor. Supporting this hypothesis, antisense suppression of the…”
Get full text

The Transmembrane Protein-tyrosine Phosphatase CD45 Is Associated with Decreased Insulin Receptor Signaling (∗) by Kulas, Donald T., Freund, Gregory G., Mooney, Robert A.

“…Overexpression of the transmembrane protein-tyrosine phosphatase (PTPase) CD45 in nonhematopoietic cells results in decreased signaling through growth factor…”
Get full text

Suppression of the Protein Tyrosine Phosphatase LAR Reduces Apolipoprotein B Secretion by McA-RH7777 Rat Hepatoma Cells by Phung, Thuy L., Mooney, Robert A., Kulas, Donald T., Sparks, Charles E., Sparks, Janet D.

“…Apolipoprotein B (apo B) secretion is reduced by insulin in rat hepatocytes. To evaluate possible mechanisms by which insulin action leads to inhibition of apo…”
Get full text