Search Results - "KULAKOVA, Liudmila"

Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein by Chao, Kinlin L., Kulakova, Liudmila, Herzberg, Osnat

“…The exact function of human gasdermin-B (GSDMB), which regulates differentiation and growth of epithelial cells, is yet to be elucidated. In human epidermal…”
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Discovery and Preclinical Development of Antigiardiasis Fumagillol Derivatives by Padia, Janak, Kulakova, Liudmila, Galkin, Andrey, Herzberg, Osnat

“…Giardiasis, caused by the intestinal parasite Giardia lamblia, is a severe diarrheal disease, endemic in poverty-stricken regions of the world, and also a…”
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Crystal structures of carbamate kinase from Giardia lamblia bound with citric acid and AMP-PNP by Lim, Kap, Kulakova, Liudmila, Galkin, Andrey, Herzberg, Osnat

“…The parasite Giardia lamblia utilizes the L-arginine dihydrolase pathway to generate ATP from L-arginine. Carbamate kinase (CK) catalyzes the last step in this…”
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High-Throughput Giardia lamblia Viability Assay Using Bioluminescent ATP Content Measurements by CHEN, Catherine Z, KULAKOVA, Liudmila, SOUTHALL, Noel, MARUGAN, Juan J, GALKIN, Andrey, AUSTIN, Christopher P, HERZBERG, Osnat, WEI ZHENG

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Epigenetic mechanisms are involved in the control of Giardia lamblia antigenic variation by Kulakova, Liudmila, Singer, Steven M., Conrad, John, Nash, Theodore E.

“…Summary Giardia lamblia, an intestinal dwelling protozoan parasite, undergoes surface antigenic variation where only one of an estimated 150 variant‐specific…”
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Structural Insight into Arginine Degradation by Arginine Deiminase, an Antibacterial and Parasite Drug Target by Galkin, Andrey, Kulakova, Liudmila, Sarikaya, Elif, Lim, Kap, Howard, Andrew, Herzberg, Osnat

“…l -Arginine deiminase (ADI) catalyzes the irreversible hydrolysis of arginine to citrulline and ammonia. ADI is involved in the first step of the most…”
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Characterization, Kinetics, and Crystal Structures of Fructose-1,6-bisphosphate Aldolase from the Human Parasite, Giardia lamblia by Galkin, Andrey, Kulakova, Liudmila, Melamud, Eugene, Li, Ling, Wu, Chun, Mariano, Patrick, Dunaway-Mariano, Debra, Nash, Theodore E., Herzberg, Osnat

“…Class I and class II fructose-1,6-bisphosphate aldolases (FBPA), glycolytic pathway enzymes, exhibit no amino acid sequence homology and utilize two different…”
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Inactivation of Microbial Arginine Deiminases by l-Canavanine by Li, Ling, Li, Zhimin, Chen, Danqi, Lu, Xuefeng, Feng, Xiaohua, Wright, Elizabeth C, Solberg, Nathan O, Dunaway-Mariano, Debra, Mariano, Patrick S, Galkin, Andrey, Kulakova, Liudmila, Herzberg, Osnat, Green-Church, Kari B, Zhang, Liwen

“…Arginine deiminase (ADI) catalyzes the hydrolytic conversion of l-arginine to ammonia and l-citrulline as part of the energy-producing l-arginine degradation…”
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Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia by Hiregange, Disha-Gajanan, Rivalta, Andre, Bose, Tanaya, Breiner-Goldstein, Elinor, Samiya, Sarit, Cimicata, Giuseppe, Kulakova, Liudmila, Zimmerman, Ella, Bashan, Anat, Herzberg, Osnat, Yonath, Ada

“…Abstract Giardiasis is a disease caused by the protist Giardia lamblia. As no human vaccines have been approved so far against it, and resistance to current…”
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Peculierities of acoousto-optic interaction in nanodimensional laser heterostructures by Kulakova, Liudmila

“…In the report, we present results of study of acousto-optic and acousto-electron interactions in active and optical resonator regions of nano-dimensional laser…”
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Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram by Galkin, Andrey, Kulakova, Liudmila, Lim, Kap, Chen, Catherine Z., Zheng, Wei, Turko, Illarion V., Herzberg, Osnat

“…Carbamate kinase from Giardia lamblia is an essential enzyme for the survival of the organism. The enzyme catalyzes the final step in the arginine dihydrolase…”
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Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein by Li, Xiaofeng, Kulakova, Liudmila, Jones, Kezzia, Toth, Eric A., Mitchell, Marina Kirkland, Mendez, Qiana, Weiner, Michael P., Fuerst, Thomas R.

“…‘Epivolve’ (epitope evolution) is an innovative paratope-evolving technology using a haptenated peptide or protein immunogen as a means of directing the in…”
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Discovery of novel antigiardiasis drug candidates by Kulakova, Liudmila, Galkin, Andrey, Chen, Catherine Z, Southall, Noel, Marugan, Juan J, Zheng, Wei, Herzberg, Osnat

“…Giardiasis is a severe intestinal parasitic disease caused by Giardia lamblia, which inflicts many people in poor regions and is the most common parasitic…”
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The rotation of the polarization plane of quantum-well heterolasers emission under the ultrasonic strain by Kulakova, Liudmila, Gorelov, Vladislav, Lutetskiy, Andrey, Averkiev, Nikita S.

“…The paper is devoted to an acousto-electron effect in the nanodimensional laser heterostructures. The effect results in a modulation of the laser emission…”
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Structural Insights into the Substrate Binding and Stereoselectivity of Giardia Fructose-1,6-bisphosphate Aldolase by Galkin, Andrey, Li, Zhimin, Li, Ling, Kulakova, Liudmila, Pal, Lipika R, Dunaway-Mariano, Debra, Herzberg, Osnat

“…Giardia lamblia fructose-1,6-bisphosphate aldolase (FBPA) is a member of the class II zinc-dependent aldolase family that catalyzes the cleavage of d-fructose…”
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Long Double-Stranded RNA Produces Specific Gene Downregulation in Giardia lamblia by Rivero, Maria R, Kulakova, Liudmila, Touz, Maria C

“…In many eukaryotes, the introduction of double-stranded RNA (dsRNA) into cells triggers the degradation of mRNAs through a post-transcriptional gene-silencing…”
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X-ray structure and kinetic properties of ornithine transcarbamoylase from the human parasite Giardia lamblia by Galkin, Andrey, Kulakova, Liudmila, Wu, Rui, Gong, Maozhen, Dunaway-Mariano, Debra, Herzberg, Osnat

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Adaptor protein complex 1 mediates the transport of lysosomal proteins from a Golgi-like organelle to peripheral vacuoles in the primitive eukaryote Giardia lamblia by Touz, María C, Kulakova, Liudmila, Nash, Theodore E

“…Giardia lamblia is an early branching protist that possesses peripheral vacuoles (PVs) with characteristics of lysosome-like organelles, located underneath the…”
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Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP. e64004 by Lim, Kap, Kulakova, Liudmila, Galkin, Andrey, Herzberg, Osnat

“…The parasite Giardia lamblia utilizes the L-arginine dihydrolase pathway to generate ATP from L-arginine. Carbamate kinase (CK) catalyzes the last step in this…”
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Epigenetic mechanisms are involved in the control of Giardia Iamblia antigenic variation by Kulakova, Liudmila, Singer, Steven M, Conrad, John, Nash, Theodore E

“…Giardia lamblia, an intestinal dwelling protozoan parasite, undergoes surface antigenic variation where only one of an estimated 150 variant-specific surface…”
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