Search Results - "KUKIDOME, Daisuke"

Hyperglycemia Induces Cellular Hypoxia through Production of Mitochondrial ROS Followed by Suppression of Aquaporin-1 by Sada, Kiminori, Nishikawa, Takeshi, Kukidome, Daisuke, Yoshinaga, Tomoaki, Kajihara, Nobuhiro, Sonoda, Kazuhiro, Senokuchi, Takafumi, Motoshima, Hiroyuki, Matsumura, Takeshi, Araki, Eiichi

“…We previously proposed that hyperglycemia-induced mitochondrial reactive oxygen species (mtROS) generation is a key event in the development of diabetic…”
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Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice by Hanatani, Satoko, Motoshima, Hiroyuki, Takaki, Yuki, Kawasaki, Shuji, Igata, Motoyuki, Matsumura, Takeshi, Kondo, Tatsuya, Senokuchi, Takafumi, Ishii, Norio, Kawashima, Junji, Kukidome, Daisuke, Shimoda, Seiya, Nishikawa, Takeshi, Araki, Eiichi

“…The induction of beige adipogenesis within white adipose tissue, known as “browning”, has received attention as a novel potential anti-obesity strategy. The…”
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Activation of AMP-Activated Protein Kinase Reduces Hyperglycemia-Induced Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial Biogenesis in Human Umbilical Vein Endothelial Cells by KUKIDOME, Daisuke, NISHIKAWA, Takeshi, SONODA, Kazuhiro, IMOTO, Koujiro, FUJISAWA, Kazuo, YANO, Miyuki, MOTOSHIMA, Hiroyuki, TAGUCHI, Tetsuya, MATSUMURA, Takeshi, ARAKI, Eiichi

“…Activation of AMP-Activated Protein Kinase Reduces Hyperglycemia-Induced Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial Biogenesis…”
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Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells by Kajihara, Nobuhiro, Kukidome, Daisuke, Sada, Kiminori, Motoshima, Hiroyuki, Furukawa, Noboru, Matsumura, Takeshi, Nishikawa, Takeshi, Araki, Eiichi

“…Aims/Introduction Overproduction of reactive oxygen species (ROS) in endothelial cells (ECs) plays a pivotal role in endothelial dysfunction. Mitochondrial ROS…”
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Impaired balance is related to the progression of diabetic complications in both young and older adults by Kukidome, Daisuke, Nishikawa, Takeshi, Sato, Miki, Nishi, Yoshiko, Shimamura, Risa, Kawashima, Junji, Shimoda, Seiya, Mizuta, Hiroshi, Araki, Eiichi

“…Abstract Aims To investigate the balance ability in younger and older adults with diabetes and evaluate the associations between balance ability and…”
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One‐hour oral glucose tolerance test plasma glucose at gestational diabetes diagnosis is a common predictor of the need for insulin therapy in pregnancy and postpartum impaired glucose tolerance by Nishikawa, Takeshi, Ono, Keiko, Hashimoto, Shoko, Kinoshita, Hiroyuki, Watanabe, Takuro, Araki, Hirotaka, Otsu, Kae, Sakamoto, Wakana, Harada, Masahiro, Toyonaga, Tetsushi, Kawakami, Shoichi, Fukuda, Jyunichiro, Haga, Yoshio, Kukidome, Daisuke, Takahashi, Takeshi, Araki, Eiich

“…Aims/Introduction Gestational diabetes mellitus (GDM) is a risk for adverse perinatal outcomes, and patients with a history of GDM have an increased risk of…”
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Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes by Kondo, Tatsuya, Miyakawa, Nobukazu, Motoshima, Hiroyuki, Hanatani, Satoko, Ishii, Norio, Igata, Motoyuki, Yoshinaga, Kayo, Kukidome, Daisuke, Senokuchi, Takafumi, Kawashima, Junji, Furukawa, Noboru, Matsumura, Takeshi, Araki, Eiichi

“…Aims/Introduction On April 14 and 16 2016, the Kumamoto area was severely damaged by several massive magnitude 7 class earthquakes. Materials and Methods To…”
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TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis by Fujisawa, Kazuo, Nishikawa, Takeshi, Kukidome, Daisuke, Imoto, Koujirou, Yamashiro, Takeshi, Motoshima, Hiroyuki, Matsumura, Takeshi, Araki, Eiichi

“…Although it has been reported that thiazolidinediones (TZDs) may reduce cardiovascular events in type 2 diabetic patients, its precise mechanism is unclear. We…”
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Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression by Igata, Motoyuki, Motoshima, Hiroyuki, Tsuruzoe, Kaku, Kojima, Kanou, Matsumura, Takeshi, Kondo, Tatsuya, Taguchi, Tetsuya, Nakamaru, Kazuhiko, Yano, Miyuki, Kukidome, Daisuke, Matsumoto, Kazuya, Toyonaga, Tetsushi, Asano, Tomoichiro, Nishikawa, Takeshi, Araki, Eiichi

“…Vascular smooth muscle cell (VSMC) proliferation is a critical event in the development and progression of vascular diseases, including atherosclerosis. We…”
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Key notes of glycemic control in elderly patients with diabetes by Kukidome, Daisuke, Araki, Eiichi

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Impact of mitochondrial ROS production in the pathogenesis of insulin resistance by Nishikawa, Takeshi, Kukidome, Daisuke, Sonoda, Kazuhiro, Fujisawa, Kazuo, Matsuhisa, Takako, Motoshima, Hiroyuki, Matsumura, Takeshi, Araki, Eiichi

“…Abstract Tumor necrosis factor-alpha (TNF-α) inhibits insulin action, in part, by activating c-jun NH2 -terminal kinases (JNK). However, the precise mechanisms…”
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Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling by IMOTO, Koujiro, KUKIDOME, Daisuke, MATSUMURA, Takeshi, ICHIJO, Hidenori, ARAKI, Eiichi, NISHIKAWA, Takeshi, MATSUHISA, Takako, SONODA, Kazuhiro, FNJISAWA, Kazuo, YANO, Miyuki, MOTOSHIMA, Hiroyuki, TAGUCHI, Tetsuya, TSURUZOE, Kaku

“…Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling Koujiro Imoto 1 , Daisuke Kukidome 1 , Takeshi…”
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Impact of mitochondrial ROS production on diabetic vascular complications by Nishikawa, Takeshi, Kukidome, Daisuke, Sonoda, Kazuhiro, Fujisawa, Kazuo, Matsuhisa, Takako, Motoshima, Hiroyuki, Matsumura, Takeshi, Araki, Eiichi

“…Abstract Vascular complications are the leading cause of morbidity and mortality in patients with diabetes. Four main molecular mechanisms have been implicated…”
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Evaluation of Urinary 8-Hydroxydeoxy-Guanosine as a Novel Biomarker of Macrovascular Complications in Type 2 Diabetes by NISHIKAWA, Takeshi, SASAHARA, Takayuki, SAKAKIDA, Michiharu, KISHIKAWA, Hideki, ARAKI, Eiichi, KIRITOSHI, Shinsuke, SONODA, Kazuhiro, SENOKUCHI, Takahumi, MATSUO, Tomoko, KUKIDOME, Daisuke, WAKE, Nakayasu, MATSUMURA, Takeshi, MIYAMURA, Nobuhiro

“…Evaluation of Urinary 8-Hydroxydeoxy-Guanosine as a Novel Biomarker of Macrovascular Complications in Type 2 Diabetes Takeshi Nishikawa , MD, PHD 1 , Takayuki…”
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Insulin requirement profiles in Japanese hospitalized subjects with type 2 diabetes treated with basal-bolus insulin therapy by Shimoda, Seiya, Okubo, Mina, Koga, Kotaro, Sekigami, Taiji, Kawashima, Junji, Kukidome, Daisuke, Igata, Motoyuki, Ishii, Norio, Shimakawa, Akiko, Matsumura, Takeshi, Motoshima, Hiroyuki, Furukawa, Noboru, Nishida, Kenro, Araki, Eiichi

“…To assess the total daily inulin dose (TDD) and contribution of basal insulin to TDD and to identify the predictive factors for insulin requirement profiles in…”
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Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice by Goto, Hideo, Nishikawa, Takeshi, Sonoda, Kazuhiro, Kondo, Tatsuya, Kukidome, Daisuke, Fujisawa, Kazuo, Yamashiro, Takeshi, Motoshima, Hiroyuki, Matsumura, Takeshi, Tsuruzoe, Kaku, Araki, Eiichi

“…We previously proposed that hyperglycemia-induced mitochondrial ROS overproduction is a key event in the development of diabetic complications. In this study,…”
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Mitochondrial reactive oxygen species by Nishikawa, Takeshi, Kukidome, Daisuke, Araki, Eiichi

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Statins Suppress Oxidized Low Density Lipoprotein-induced Macrophage Proliferation by Inactivation of the Small G Protein-p38 MAPK Pathway by Senokuchi, Takafumi, Matsumura, Takeshi, Sakai, Masakazu, Yano, Miyuki, Taguchi, Tetsuya, Matsuo, Tomoko, Sonoda, Kazuhiro, Kukidome, Daisuke, Imoto, Koujiroh, Nishikawa, Takeshi, Kim-Mitsuyama, Shokei, Takuwa, Yoh, Araki, Eiichi

“…Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) ameliorate atherosclerotic diseases. Macrophages play an important role in the…”
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A Case of Cortisol Producing Adrenal Adenoma Associated with a Latent Aldosteronoma: Usefulness of the ACTH Loading Test for the Detection of Covert Aldosteronism in Overt Cushing Syndrome by Kukidome, Daisuke, Miyamura, Nobuhiro, Sakakida, Kourin, Shimoda, Seiya, Shigematu, Yoshinori, Nishi, Kazuhiko, Yamashita, Yasuyuki, Eto, Masatoshi, Sasano, Hironobu, Araki, Eiichi

“…A 36-year-old woman with Cushing syndrome was evaluated for coexisting hyperaldosteronism, which was suggested by an abnormal response of the…”
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Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein by Senokuchi, Takafumi, Matsumura, Takeshi, Sakai, Masakazu, Matsuo, Tomoko, Yano, Miyuki, Kiritoshi, Shinsuke, Sonoda, Kazuhiro, Kukidome, Daisuke, Nishikawa, Takeshi, Araki, Eiichi

“…We previously reported that oxidized low-density lipoprotein (Ox-LDL)-induced expression of granulocyte/macrophage colony-stimulating factor (GM-CSF) via PKC,…”
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