Search Results - "KUIJPERS, R. W. A. M"

Orbit-Infiltrating Mast Cells, Monocytes, and Macrophages Produce PDGF Isoforms that Orchestrate Orbital Fibroblast Activation in Graves' Ophthalmopathy by van Steensel, L, Paridaens, D, van Meurs, M, van Hagen, P. M, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, Hooijkaas, H, Dik, W. A

“…Purpose: Platelet-derived growth factors (PDGF) are regulators of fibroblast activity that may be involved in the pathophysiology of Graves' ophthalmopathy…”
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PDGF Enhances Orbital Fibroblast Responses to TSHR Stimulating Autoantibodies in Graves' Ophthalmopathy Patients by van Steensel, L, Hooijkaas, H, Paridaens, D, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, van Hagen, P. M, Dik, W. A

“…Purpose: Thyroid-stimulating hormone receptor (TSHR) stimulating autoantibodies are associated with Graves' ophthalmopathy (GO), the orbital manifestation of…”
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Are Patients at Risk for Recurrent Disease Activity After Switching From Remicade® to Remsima®? An Observational Study by Xue, Laixi, van Bilsen, K., Schreurs, M. W. J., van Velthoven, M. E. J., Missotten, T. O., Thiadens, A. A. H. J., Kuijpers, R. W. A. M., van Biezen, P., Dalm, V. A. S. H., van Laar, J. A. M., Hermans, M. A. W., Dik, W. A., van Daele, P. L. A., van Hagen, P. M.

“…Background: Since the late ‘90s, infliximab (Remicade ® ) is being used successfully to treat patients with several non-infectious immune mediated inflammatory…”
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Autoantibodies to photoreceptor membrane proteins and outer plexiform layer in patients with cancer‐associated retinopathy by PEEK, R., DIJKSTRA, B. G., MEEK, B., KUIJPERS, R. W. A. M.

“…SUMMARY Cancer‐associated retinopathy (CAR) is a paraneoplastic syndrome that is characterized by degeneration of the retina as a remote effect of cancer…”
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Low prevalence of NOD2 SNPs in Behçet's disease suggests protective association in Caucasians by Kappen, Jasper H., Wallace, Graham R., Stolk, Lisette, Rivadeneira, Fernando, Uitterlinden, Andre G., van Daele, Paul L. A., Laman, Jon D., Kuijpers, Robert W. A. M., Baarsma, Goitze Seerp, Stanford, Miles R., Fortune, Farida, Madanat, Wafa, van Hagen, Petrus Martin, van Laar, Jan A. M.

“…Objective. It has been shown previously that three nucleotide-binding oligomerization domain containing 2 (NOD2) variants (Arg702Trp, Gly908Arg and Lue1007fs)…”
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Adhesion molecules in iris biopsy specimens from patients with uveitis by Heij, Ellen La, Kuijpers, Robert W A M, Baarsma, Seerp G, Kijlstra, Aize, van der Weiden, Marcel, Mooy, Cornelia M

“…BACKGROUND/AIMS Earlier studies on intraocular tissue have demonstrated that T lymphocytes play a major role in the pathogenesis of uveitis. Adhesion molecules…”
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Anti-TNF-α therapy for sight threatening uveitis by Lindstedt, E W, Baarsma, G S, Kuijpers, R W A M, van Hagen, P M

“…Aim: To describe the effect of additional treatment with anti-TNF-α therapy in a case series of 13 patients with serious sight threatening uveitis. Methods: 13…”
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Whole orbital tissue culture identifies imatinib mesylate and adalimumab as potential therapeutics for Graves' ophthalmopathy by van Steensel, Leendert, van Hagen, P Martin, Paridaens, Dion, Kuijpers, Robert W A M, van den Bosch, Willem A, Drexhage, Hemmo A, Hooijkaas, Herbert, Dik, Willem A

“…Biologicals and small inhibitory molecules are used to treat inflammatory diseases, but their efficacy varies upon clinical application. Using a whole orbital…”
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Thrombocytopenia due to platelet glycoprotein IIb/IIIa-reactive autoantibodies non-reactive with platelets from EDTA blood by Kuijpers, R W, Ouwehand, W H, Peelen, W, Michiels, J J, Engelfriet, C P, von dem Borne, A E

“…We describe 2 patients with thrombocytopenia and autoantibodies in the blood against platelet membrane glycoprotein (GP) IIb/IIIa, in whom reactivity of the…”
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Anti-TNF-α therapy for sight threatening uveititis by LINDSTEDT, E. W, BAARSMA, G. S, KUIJPERS, R. W. A. M, VAN HAGEN, P. M

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Anti-TNF-  therapy for sight threatening uveitis by Lindstedt, E W

“…Aim: To describe the effect of additional treatment with anti-TNF-α therapy in a case series of 13 patients with serious sight threatening uveitis. Methods: 13…”
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Somatostatin and somatostatin receptors in retinal diseases by van Hagen, PM, Baarsma, GS, Mooy, CM, Ercoskan, EM, ter Averst, E, Hofland, LJ, Lamberts, SW, Kuijpers, RW

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Somatostatin Receptor 2A Expression in Choroidal Neovascularization Secondary to Age-Related Macular Degeneration by Lambooij, Antoinette C, Kuijpers, Robert W. A. M, van Lichtenauer-Kaligis, Elgin G. R, Kliffen, Mike, Baarsma, G. Seerp, van Hagen, P. Martin, Mooy, Cornelia M

“…The growth of ocular neovascularization is regulated by a balance between stimulating and inhibiting growth factors. Somatostatin affects angiogenesis by…”
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Adult respiratory distress syndrome after experimental intravenous γ-globulin concentrate and monocyte-reactive IgG antibodies by Kuijpers, RWAM, Dooren, MC, Ouwehand, WH, Verhoeven, AJ, von dem Borne, AEG Kr

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Experience with cyclosporine in endogenous uveitis posterior: Medical Milestones in Immunosuppression by HESSELINK, D. A, BAARSMA, G. S, KUIJPERS, R. W. A. M, VAN HAGEN, P. M

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Experience with cyclosporine in endogenous uveitis posterior by Hesselink, D.A, Baarsma, G.S, Kuijpers, R.W.A.M, van Hagen, P.M

“…Treatment with cyclosporine (CsA) has considerably improved the visual prognosis of patients suffering from endogenous posterior uveitis (EPU). However, the…”
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Somatostatin-related therapeutics in ophthalmology: a review by Missotten, T, Baarsma, G S, Kuijpers, R W A M, van den Born, L I, van der Born, L I, van der Loos, T, Croxen, R, Hofland, L J, van Hagen, P M

“…Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the…”
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Somatostatin in diabetic retinopathy by Croxen, R, Baarsma, G S, Kuijpers, R W A M, van Hagen, P M

“…Diabetic retinopathy is a leading cause of legal blindness in the adult population (30-70 year olds). The anatomical changes that occur in the retina during…”
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Single Point Mutation in Human Glycoprotein IIIa Is Associated With a New Platelet-Specific Alloantigen (Mo) Involved in Neonatal Alloimmune Thrombocytopenia by Kuijpers, R.W.A.M., Simsek, S., Faber, N.M., Goldschmeding, R., Wermerkerken, R.K.V. van, Borne, A.E.G. Kr. von dem

“…Here we describe a new platelet-specific alloantigen that was identified in a case of neonatal alloimmune thrombocytopenia. This antigen has provisionally been…”
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Adult respiratory distress syndrome after experimental intravenous (gamma-globulin) concentrate and monocyte-reactive IgG antibodies by Dooren, M C, Ouwehand, W H, Verhoeven, A J, A E G Kr von dem Borne, R W A M Kuijpers

“…Dooren et al discuss a case in which adult respiratory distress syndrome in a healthy patient after monocyte-reactive IgG alloantibodies was not due to…”
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