Search Results - "KUHL, Uwe"

Complication Rate of Right Ventricular Endomyocardial Biopsy via the Femoral Approach : A Retrospective and Prospective Study Analyzing 3048 Diagnostic Procedures Over an 11-Year Period by HOLZMANN, Matthias, NICKO, Alexander, PAUSCHINGER, Matthias, KÜHL, Uwe, NOUTSIAS, Michel, POLLER, Wolfgang, HOFFMANN, Wolfgang, MORGUET, Andreas, WITZENBICHLER, Bernhard, TSCHÖPE, Carsten, SCHULTHEISS, Heinz-Peter

“…An unequivocal diagnosis of myocarditis and cardiac virus persistence is based on histological, immunohistological, and molecular biological analyses of…”
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Long-term outcome of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy after immunosuppressive therapy by Escher, Felicitas, Kühl, Uwe, Lassner, Dirk, Poller, Wolfgang, Westermann, Dirk, Pieske, Burkert, Tschöpe, Carsten, Schultheiss, Heinz-Peter

“…Aim To analyze the long-term outcome after immunosuppressive treatment of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy…”
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Suspected chronic myocarditis at cardiac MR: diagnostic accuracy and association with immunohistologically detected inflammation and viral persistence by Gutberlet, Matthias, Spors, Birgit, Thoma, Tobias, Bertram, Henriette, Denecke, Timm, Felix, Roland, Noutsias, Michel, Schultheiss, Heinz-Peter, Kühl, Uwe

“…To retrospectively compare the diagnostic accuracy of three cardiac magnetic resonance (MR) imaging approaches for the detection of histologic and…”
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Long-Term Risk of Recurrence, Morbidity and Mortality in Giant Cell Myocarditis by Maleszewski, Joseph J., MD, Orellana, Victor M., MD, Hodge, David O., MS, Kuhl, Uwe, MD, Schultheiss, Heinz-Peter, MD, Cooper, Leslie T., MD

“…Giant cell myocarditis (GCM) is a rare disorder in which survival beyond 1 year without heart transplantation is uncommon. Long-term follow-up data on those…”
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Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis by Pappritz, Kathleen, Lin, Jie, El‐Shafeey, Muhammad, Fechner, Henry, Kühl, Uwe, Alogna, Alessio, Spillmann, Frank, Elsanhoury, Ahmed, Schulz, Rainer, Tschöpe, Carsten, Van Linthout, Sophie

“…Aim The acute phase of a coxsackievirus 3 (CVB3)‐induced myocarditis involves direct toxic cardiac effects and the systemic activation of the immune system,…”
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Human Parvovirus B19 (B19V) Up-regulates CXCR4 Surface Expression of Circulating Angiogenic Cells: Implications for Cardiac Ischemia in B19V Cardiomyopathy by Schmidt-Lucke, Caroline, Zobel, Thomas, Escher, Felicitas, Tschöpe, Carsten, Lassner, Dirk, Kühl, Uwe, Gubbe, Knut, Volk, Hans-Dieter, Schultheiss, Heinz-Peter

“…Human parvovirus B19 (B19V) infection is responsible for apoptosis of angiogenic cells and dysfunctional endogenous vascular repair with secondary end-organ…”
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Targeting CD20+ B-lymphocytes in inflammatory dilated cardiomyopathy with rituximab improves clinical course: a case series by Tschöpe, Carsten, Van Linthout, Sophie, Spillmann, Frank, Posch, Maximilian G, Reinke, Petra, Volk, Hans-Dieter, Elsanhoury, Ahmed, Kühl, Uwe

“…Abstract Background  The aetiology of dilated cardiomyopathy (DCM) is highly heterogeneous including genetic and/or acquired (infective, toxic, immune,…”
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New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy by Kasner, Mario, Escher, Felicitas, Kühl, Uwe, Heymer, Johannes, Wilkenshoff, Ursula, Tschöpe, Carsten, Schultheiss, Heinz-Peter

“…Background. The diagnosis of acute myocarditis (AMC) and inflammatory cardiomyopathy (DCMi) can be difficult. Speckle tracking echocardiography with accurate…”
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Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection by Tweedy, Joshua, Spyrou, Maria Alexandra, Pearson, Max, Lassner, Dirk, Kuhl, Uwe, Gompels, Ursula A

“…Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated…”
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Viral Myocarditis: Diagnosis, Aetiology and Management by Kühl, Uwe, Schultheiss, Heinz-Peter

“…Myocarditis is an inflammatory disease of the cardiac muscle caused by myocardial infiltration of immunocompetent cells following any kind of cardiac injury…”
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Cardiac Migration of Endogenous Mesenchymal Stromal Cells in Patients with Inflammatory Cardiomyopathy by Tschöpe, Carsten, Schultheiss, Heinz-Peter, Ringe, Jochen, Miteva, Kapka, Kühl, Uwe, Van Linthout, Sophie, Escher, Felicitas, Schmidt-Lucke, Caroline, Zobel, Thomas

“…Introduction. Mesenchymal stromal cells (MSC) have immunomodulatory features. The aim of this study was to investigate the migration and homing potential of…”
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Absent MicroRNAs in Different Tissues of Patients with Acquired Cardiomyopathy by Siegismund, Christine S., Rohde, Maria, Kühl, Uwe, Escher, Felicitas, Schultheiss, Heinz Peter, Lassner, Dirk

“…MicroRNAs （miRNAs） can be found in a wide range of tissues and body fluids, and their specific signatures can be used to determine diseases or predict clinical…”
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Expression of cell adhesion molecules in dilated cardiomyopathy : Evidence for endothelial activation in inflammatory cardiomyopathy by NOUTSIAS, M, SEEBERG, B, SCHULTHEISS, H.-P, KÜHL, U

“…Dilated cardiomyopathy (DCM) is pathogenically linked to inflammatory cardiomyopathy (InfCM), which is characterized by intramyocardial infiltration. The…”
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Differential aspects of endothelial function of the coronary microcirculation considering myocardial virus persistence, endothelial activation, and myocardial leukocyte infiltrates by VALLBRACHT, Katja B, SCHWIMMBECK, Peter L, KÜHL, Uwe, RAUCH, Ursula, SEEBERG, Bettina, SCHULTHEISS, Heinz-Peter

“…Viral cardiomyopathy resulting from myocardial virus persistence can be associated with inflammatory immune responses that involve the myocardium and coronary…”
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Diastolic Tissue Doppler Indexes Correlate With the Degree of Collagen Expression and Cross-Linking in Heart Failure and Normal Ejection Fraction by Kasner, Mario, MD, MSc, Westermann, Dirk, MD, Lopez, Begoña, DSc, Gaub, Regina, MD, Escher, Felicitas, MD, Kühl, Uwe, MD, Schultheiss, Heinz-Peter, MD, Tschöpe, Carsten, MD

“…Objectives We attempted to correlate echocardiographic analysis of diastolic function with changes of myocardial collagen in middle-aged patients with heart…”
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Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies by Noutsias, Michel, Rohde, Maria, Block, Andrea, Klippert, Katrin, Lettau, Olga, Blunert, Katja, Hummel, Michael, Kühl, Uwe, Lehmkuhl, Hans, Hetzer, Roland, Rauch, Ursula, Poller, Wolfgang, Pauschinger, Matthias, Schultheiss, Heinz P, Volk, Hans D, Kotsch, Katja

“…Due to the limited RNA amounts from endomyocardial biopsies (EMBs) and low expression levels of certain genes, gene expression analyses by conventional…”
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Bromocriptine for the treatment of peripartum cardiomyopathy: a multicentre randomized study by Hilfiker-Kleiner, Denise, Haghikia, Arash, Berliner, Dominik, Vogel-Claussen, Jens, Schwab, Johannes, Franke, Annegret, Schwarzkopf, Marziel, Ehlermann, Philipp, Pfister, Roman, Michels, Guido, Westenfeld, Ralf, Stangl, Verena, Kindermann, Ingrid, Kühl, Uwe, Angermann, Christiane E, Schlitt, Axel, Fischer, Dieter, Podewski, Edith, Böhm, Michael, Sliwa, Karen, Bauersachs, Johann

“…An anti-angiogenic cleaved prolactin fragment is considered causal for peripartum cardiomyopathy (PPCM). Experimental and first clinical observations suggested…”
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Antimyosin autoantibodies are associated with deterioration of systolic and diastolic left ventricular function in patients with chronic myocarditis by Lauer, Bernward, Schannwell, Mira, Kühl, Uwe, Strauer, Bodo-Eckhard, Schultheiss, Heinz-Peter

“…OBJECTIVES The study evaluates the clinical course and the development of systolic and diastolic left ventricular function in patients with chronic myocarditis…”
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Endothelium-dependent flow-mediated vasodilation of systemic arteries is impaired in patients with myocardial virus persistence by Vallbracht, Katja B, Schwimmbeck, Peter L, Kühl, Uwe, Seeberg, Bettina, Schultheiss, Heinz-Peter

“…Myocardial virus persistence is frequently observed in patients with cardiomyopathy. Endothelial dysfunction in patients with cardiomyopathy is associated with…”
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Immunohistological detection of Parvovirus B19 capsid proteins in endomyocardial biopsies from dilated cardiomyopathy patients by Escher, Felicitas, Kuhl, Uwe, Sabi, Titus, Suckau, Lennart, Lassner, Dirk, Poller, Wolfgang, Schultheiss, Heinz-Peter, Noutsias, Michel

“…Parvovirus B19 (B19V) has been identified as the most common virus in dilated cardiomyopathy (DCM) patients by PCR techniques. We investigated the…”
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