Search Results - "KUGLER, Christian"
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Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
Published in Respiratory research (24-07-2018)“…The origin of collagen-producing cells in lung fibrosis is unclear. The involvement of embryonic signaling pathways has been acknowledged and…”
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Human Lung Tissue Explants Reveal Novel Interactions during Legionella pneumophila Infections
Published in Infection and Immunity (01-01-2014)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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3
Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers
Published in BMC cancer (06-08-2018)“…ADAMs (a disintegrin and metalloproteinase) have long been associated with tumor progression. Recent findings indicate that members of the closely related…”
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4
Mycobacteria infect different cell types in the human lung and cause species dependent cellular changes in infected cells
Published in BMC pulmonary medicine (23-01-2016)“…Mycobacterial infections remain a significant cause of morbidity and mortality worldwide. Due to limitations of the currently available model systems, there…”
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Identification of molecular signatures associated with early relapse after complete resection of lung adenocarcinomas
Published in Scientific reports (05-05-2021)“…The only potentially curative treatment for lung adenocarcinoma patients remains complete resection of early-stage tumors. However, many patients develop…”
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Mechanisms of cilia-driven transport in the airways in the absence of mucus
Published in American journal of respiratory cell and molecular biology (01-07-2014)“…Airway mucus is thought to be required for the clearance of inhaled particles by mucociliary transport, but this view has recently been challenged. To test if…”
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Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer
Published in Journal for immunotherapy of cancer (01-02-2021)“…BackgroundThe interplay of immune and cancer cells takes place in the tumor microenvironment where multiple signals are exchanged. The transforming growth…”
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Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy
Published in Clinical epigenetics (12-11-2019)“…Recently, it was shown that the epigenetic age of non-small cell lung cancer (NSCLC) tissues is different from the chronological age of patients. Here, we…”
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Air exposure and cell differentiation are essential for investigation of SARS-CoV-2 entry genes in human primary airway epithelial cells in vitro
Published in Frontiers in medicine (06-09-2022)“…BackgroundIn-vitro models of differentiated primary human airway epithelial cells are a valuable tool to study severe acute respiratory syndrome coronavirus 2…”
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10
Postoperative outcome after palliative treatment of malignant pleural effusion
Published in Thoracic cancer (01-08-2022)“…Background The objective of this nationwide, registry‐based study was to compare the two most frequently used procedures for the palliative treatment of a…”
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Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score
Published in Discover. Oncology (03-10-2023)“…Background Lung cancer (LC) causes more deaths worldwide than any other cancer type. Despite advances in therapeutic strategies, the fatality rate of LC cases…”
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Epigenetic modifications of the VGF gene in human non-small cell lung cancer tissues pave the way towards enhanced expression
Published in Clinical epigenetics (28-11-2017)“…Hwang et al. recently showed that VGF substantially contributes to the resistance of human lung cancer cells towards epidermal growth factor receptor kinase…”
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Acute Pulmonary Artery Obstruction as the Primary Manifestation of a Rapidly Growing Intimal Sarcoma in a 54-Year-Old Patient
Published in The Thoracic and cardiovascular surgeon reports (01-12-2016)“…Abstract Pulmonary artery sarcoma is a rare malignant neoplasm that is often misdiagnosed and most often only recognized postmortem during the autopsy. We…”
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14
Expression of CEACAM1 in Adenocarcinoma of the Lung: A Factor of Independent Prognostic Significance
Published in Journal of clinical oncology (01-11-2002)“…To evaluate the prognostic relevance of CEACAM1 and sialyl Lewis X expression in adenocarcinomas of the lung. Paraffin wax sections of 93 patients with…”
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Surgical Technique of Lower Lobe Lung Transplantation
Published in The Annals of thoracic surgery (01-08-2011)“…Among patients with end-stage lung disease awaiting lung transplantation, pediatric and small adult patients have a significantly lower chance of getting…”
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Total Pulmonary Vein Occlusion as a Consequence of Catheter Ablation for Atrial Fibrillation Mimicking Primary Lung Disease
Published in Journal of cardiovascular electrophysiology (01-04-2003)“…Introduction: Catheter ablation has recently been used for curative treatment of atrial fibrillation. Methods and Results: Three of 239 patients who underwent…”
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Lectin histochemistry of metastatic adenocarcinomas of the lung
Published in Lung cancer (Amsterdam, Netherlands) (01-06-2007)“…Summary Background Several clinical studies indicate that primary tumour cells with high metastatic potential often show aberrant glycosylation as detected by…”
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18
Tracheomalacia
Published in Thoracic surgery clinics (01-02-2014)“…Tracheomalacia is excessive collapsibility of the trachea, typically during expiration. Congenital forms are associated with severe symptoms. Milder forms…”
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Minimal-invasive thoracic surgery in pediatric patients
Published in Journal of visualized surgery (11-01-2018)“…During the last two decades, there was a tremendous development of video-assisted thoracoscopic surgery (VATS), especially in the field of video-assisted lung…”
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Intraoperative Determination of Bronchus Stump and Anastomosis Perfusion with Hyperspectral Imaging
Published in Surgical innovation (01-06-2023)“…Background The intraoperative evaluation of bronchus perfusion is limited. Hyperspectral Imaging (HSI) is a newly established intraoperative imaging technique…”
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