Search Results - "KUGAEVSKAYA, Elena V"

Interstitial collagenase MMP-1 and EMMPRIN in cell lines and in clinical specimens of cervical squamous cell carcinoma by Solovyeva, Nina I., Timoshenko, Olga S., Kugaevskaya, Elena V., Gureeva, Tatyana A.

“…Background The aim of this study was to elucidate the features of the expression of matrix metalloproteinases inducer—EMMPRIN (EMN) and matrix…”
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N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-β(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer’s disease by Kugaevskaya, Elena V., Veselovsky, Alexander V., Indeykina, Maria I., Solovyeva, Nina I., Zharkova, Maria S., Popov, Igor A., Nikolaev, Eugene N., Mantsyzov, Alexey B., Makarov, Alexander A., Kozin, Sergey A.

“…Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder. Amyloid-β (Aβ) aggregation is likely to be the major cause of AD. In contrast to…”
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Urokinase-Type Plasminogen Activator System in Norm and in Life-Threatening Processes (Review) by Kugaevskaya, Elena V., Gureeva, Tatiana A., Timoshenko, Olga S., Solovyeva, Nina I.

“…The multifunctional urokinase-type plasminogen activator system (uPA-system) includes serine proteinase — uPA or urokinase, its receptor (uPAR) and two…”
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Fine Epitope Mapping of Monoclonal Antibody 5F1 Reveals Anticatalytic Activity toward the N Domain of Human Angiotensin-Converting Enzyme by Danilov, Sergei M, Watermeyer, Jean M, Balyasnikova, Irina V, Gordon, Kerry, Kugaevskaya, Elena V, Elisseeva, Yulia E, Albrecht, Ronald F, Sturrock, Edward D

“…Angiotensin I-converting enzyme (ACE, peptidyl dipeptidase, EC 3.4.15.2) is a key enzyme in cardiovascular pathophysiology. A wide spectrum of monoclonal…”
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Computer-Aided Selection of Potential Antihypertensive Compounds with Dual Mechanism of Action by Lagunin, Alexey A, Gomazkov, Oleg A, Filimonov, Dmitrii A, Gureeva, Tatyana A, Dilakyan, Elvira A, Kugaevskaya, Elena V, Elisseeva, Yulia E, Solovyeva, Nina I, Poroikov, Vladimir V

“…The prediction of biological activity spectra for substances as an approach for searching compounds with complex mechanisms of action was studied. New…”
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Epitope mapping of the domains of human angiotensin converting enzyme by Kugaevskaya, Elena V., Kolesanova, Ekaterina F., Kozin, Sergey A., Veselovsky, Alexander V., Dedinsky, Ilya R., Elisseeva, Yulia E.

“…Somatic angiotensin converting enzyme (sACE), contains in its single chain two homologous domains (called N- and C-domains), each bearing a functional…”
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The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Aβ-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Toropygin, Ilya Yu, Kugaevskaya, Elena V., Mirgorodskaya, Olga A., Elisseeva, Yulia E., Kozmin, Yuri P., Popov, Igor A., Nikolaev, Eugene N., Makarov, Alexander A., Kozin, Sergey A.

“…Chronic imbalance between production and degradation of the human amyloid‐beta peptide (Aβ) is assumed to play an important role in pathogenesis of Alzheimer's…”
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The Role of Stromal Proteolytic Systems in Cancer Progression (Review) by Kugaevskaya, E. V., Timoshenko, O. S., Gureeva, T. A., Solovieva, N. I.

“…Oncological diseases belong to life-threatening pathologies being the second most frequent cause of morbidity and mortality after cardiovascular diseases…”
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The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Toropygin, Ilya Yu, Kugaevskaya, Elena V, Mirgorodskaya, Olga A, Elisseeva, Yulia E, Kozmin, Yuri P, Popov, Igor A, Nikolaev, Eugene N, Makarov, Alexander A, Kozin, Sergey A

“…Chronic imbalance between production and degradation of the human amyloid-beta peptide (Abeta) is assumed to play an important role in pathogenesis of…”
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Computer-aided selection of potential antihypertensive compounds with dual mechanism of action by LAGUNIN, Alexey A, GOMAZKOV, Oleg A, FILIMONOV, Dmitrii A, GUREEVA, Tatyana A, DILAKYAN, Elvira A, KUGAEVSKAYA, Elena V, ELISSEEVA, Yulia E, SOLOVYEVA, Nina I, POROIKOV, Vladimir V

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