Search Results - "KUBOTA, Yoshiko"

Modulatory Mechanism of Nociceptive Neuronal Activity by Dietary Constituent Resveratrol by Takeda, Mamoru, Takehana, Shiori, Sekiguchi, Kenta, Kubota, Yoshiko, Shimazu, Yoshihito

“…Changes to somatic sensory pathways caused by peripheral tissue, inflammation or injury can result in behavioral hypersensitivity and pathological pain, such…”
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Acute intravenous administration of dietary constituent theanine suppresses noxious neuronal transmission of trigeminal spinal nucleus caudalis in rats by Takehana, Shiori, Kubota, Yoshiko, Uotsu, Nobuo, Yui, Kei, Shimazu, Yoshihito, Takeda, Mamoru

“…Highlights • Intravenous theanine injection suppresses nociceptive SpVc WDR neuronal excitability. • Neuronal firing rates were dose-dependently inhibited by…”
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Systemic administration of resveratrol suppress the nociceptive neuronal activity of spinal trigeminal nucleus caudalis in rats by Takehana, Shiori, Sekiguchi, Kenta, Inoue, Maki, Kubota, Yoshiko, Ito, Yukihiko, Yui, Kei, Shimazu, Yoshihito, Takeda, Mamoru

“…Highlights • Intravenous resveratrol administration suppress trigeminal WDR neuronal excitability. • Suppressive effect of resveratrol was dose-dependent and…”
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The dietary constituent resveratrol suppresses nociceptive neurotransmission via the NMDA receptor by Takehana, Shiori, Kubota, Yoshiko, Uotsu, Nobuo, Yui, Kei, Iwata, Koichi, Shimazu, Yoshihito, Takeda, Mamoru

“…Background Although we have previously reported that intravenous resveratrol administration inhibits the nociceptive neuronal activity of spinal trigeminal…”
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Resveratrol attenuates inflammation-induced hyperexcitability of trigeminal spinal nucleus caudalis neurons associated with hyperalgesia in rats by Sekiguchi, Kenta, Takehana, Shiori, Shibuya, Eri, Matsuzawa, Nichiwa, Hidaka, Shiori, Kanai, Yurie, Inoue, Maki, Kubota, Yoshiko, Shimazu, Yoshihito, Takeda, Mamoru

“…Background Resveratrol, a component of red wine, has been reported to decrease prostaglandin E2 production by inhibiting the cyclooxygenase-2 cascade and to…”
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Suppression of hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia following systemic administration of lutein via inhibition of cyclooxygenase-2 cascade signaling by Syoji, Yumiko, Kobayashi, Ryota, Miyamura, Nako, Hirohara, Tsukasa, Kubota, Yoshiko, Uotsu, Nobuo, Yui, Kei, Shimazu, Yoshihito, Takeda, Mamoru

“…Lutein is a dietary constituent known to inhibit inflammation; however, its effect on nociceptive neuron-associated hyperalgesia remains to be determined. The…”
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Glucocorticoid suppresses dendritic spine development mediated by down-regulation of caldesmon expression by Tanokashira, Daisuke, Morita, Tsuyoshi, Hayashi, Ken'ichiro, Mayanagi, Taira, Fukumoto, Kentaro, Kubota, Yoshiko, Yamashita, Toshihide, Sobue, Kenji

“…Glucocorticoids (GCs) mediate the effects of stress to cause structural plasticity in brain regions such as the hippocampus, including simplification of…”
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XRCC1 genotype and breast cancer : Functional studies and epidemiologic data show interactions between XRCC1 codon 280 his and smoking by PACHKOWSKI, Brian F, WINKEL, Scott, KUBOTA, Yoshiko, SWENBERG, James A, MILLIKAN, Robert C, NAKAMURA, Jun

“…Tobacco smoke produces oxidative and alkylative DNA damage that necessitates repair by base excision repair coordinated by X-ray cross-complementing gene 1…”
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The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability by Takanami, Takako, Nakamura, Jun, Kubota, Yoshiko, Horiuchi, Saburo

“…The contribution of three single nucleotide polymorphisms (SNPs) that substitute amino acids in the X-ray repair cross-complementing gene 1 (XRCC1) protein,…”
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CLPX regulates mitochondrial fatty acid β-oxidation in liver cells by Suzuki, Ko, Kubota, Yoshiko, Kaneko, Kiriko, Kamata, Costantine Chasama, Furuyama, Kazumichi

“…Mitochondrial fatty acid oxidation (β-oxidation) is an essential metabolic process for energy production in eukaryotic cells, but the regulatory mechanisms of…”
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Novel Mechanisms for Heme-dependent Degradation of ALAS1 Protein as a Component of Negative Feedback Regulation of Heme Biosynthesis by Kubota, Yoshiko, Nomura, Kazumi, Katoh, Yasutake, Yamashita, Rina, Kaneko, Kiriko, Furuyama, Kazumichi

“…In eukaryotic cells, heme production is tightly controlled by heme itself through negative feedback-mediated regulation of nonspecific 5-aminolevulinate…”
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Induction of Osteogenic Protein-1 Expression by Interleukin-1β in Cultured Rabbit Articular Chondrocytes by YOSHIDA, SATOSHI, KUBOTA, YOSHIKO, TOBA, TAMOTSU, HORIUCHI, SABURO, SHIMAMURA, TADASHI

“…To elucidate the effects of interleukin-1β (IL-1β) on osteogenic protein-1 (OP-1) gene expression in a polylayer culture of rabbit articular chondrocytes, we…”
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Establishment of a cell model of X-linked sideroblastic anemia using genome editing by Kaneko, Kiriko, Kubota, Yoshiko, Nomura, Kazumi, Hayashimoto, Haruka, Chida, Taisei, Yoshino, Naoto, Wayama, Marina, Ogasawara, Katsutoshi, Nakamura, Yukio, Tooyama, Ikuo, Furuyama, Kazumichi

“…•An in vitro cell model for X-linked sideroblastic anemia (XLSA) was established.•Ring sideroblasts were observed reproducibly in ALAS2 knockdown (HA2low)…”
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Induction of osteogenic protein-1 expression by interleukin-1beta in cultured rabbit articular chondrocytes by Yoshida, Satoshi, Kubota, Yoshiko, Toba, Tamotsu, Horiuchi, Saburo, Shimamura, Tadashi

“…To elucidate the effects of interleukin-1beta (IL-1beta) on osteogenic protein-1 (OP-1) gene expression in a polylayer culture of rabbit articular…”
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SNF2H interacts with XRCC1 and is involved in repair of H2O2-induced DNA damage by Kubota, Yoshiko, Shimizu, Shinji, Yasuhira, Shinji, Horiuchi, Saburo

“…•CK2-dependent phosphorylation of XRCC1 is crucial for its interaction with SNF2H.•Foci-formation of XRCC1 and PAR in response to H2O2 treatment is dependent…”
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Down-regulation of c-myc andbcl-2 gene expression in PU.1-induced apoptosis in murine erythroleukemia cells by Kihara-Negishi, Fumiko, Yamada, Toshiyuki, Kubota, Yoshiko, Kondoh, Nobuo, Yamamoto, Hitomi, Abe, Masaaki, Shirai, Toshikazu, Hashimoto, Yoshiyuki, Oikawa, Tsuneyuki

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Localization of X-ray cross complementing gene 1 protein in the nuclear matrix is controlled by casein kinase II-dependent phosphorylation in response to oxidative damage by Kubota, Yoshiko, Takanami, Takako, Higashitani, Atsushi, Horiuchi, Saburo

“…Base excision repair/single strand break repair (BER/SSBR) of damaged DNA is a highly efficient process. X-ray cross complementing protein 1 (XRCC1) functions…”
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Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein by Kubota, Y., Nash, R. A., Klungland, A., Schär, P., Barnes, D. E., Lindahl, T.

“…Repair of a uracil‐guanine base pair in DNA has been reconstituted with the recombinant human proteins uracil‐DNA glycosylase, apurinic/apyrimidinic…”
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Independent roles of XRCC1’s two BRCT motifs in recovery from methylation damage by Kubota, Yoshiko, Horiuchi, Saburo

“…XRCC1 is known to be involved in base excision repair (BER)/single-strand break repair (SSBR) through interaction with other BER enzymes. Hypersensitivity of…”
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Comparative study of embryonic thermoresistance of two inbred strains of the medaka (Oryzias latipes) by KUBOTA, Y, SHIMA, A

“…By using inbred strains (HO4C and HB32C) of the medaka, Oryzias latipes , the involvement of genetic factor(s) in the determination of thermoresistance of fish…”
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