Search Results - "KUBAN, Karl C. K"

Placental genomics mediates genetic associations with complex health traits and disease by Bhattacharya, Arjun, Freedman, Anastasia N., Avula, Vennela, Harris, Rebeca, Liu, Weifang, Pan, Calvin, Lusis, Aldons J., Joseph, Robert M., Smeester, Lisa, Hartwell, Hadley J., Kuban, Karl C. K., Marsit, Carmen J., Li, Yun, O’Shea, T. Michael, Fry, Rebecca C., Santos, Hudson P.

“…As the master regulator in utero , the placenta is core to the Developmental Origins of Health and Disease (DOHaD) hypothesis but is historically understudied…”
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Placental CpG methylation of infants born extremely preterm predicts cognitive impairment later in life by Tilley, Sloane K, Martin, Elizabeth M, Smeester, Lisa, Joseph, Robert M, Kuban, Karl C K, Heeren, Tim C, Dammann, Olaf U, O'Shea, T Michael, Fry, Rebecca C

“…The placenta is the central regulator of maternal and fetal interactions. Perturbations of placental structure and function have been associated with adverse…”
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Prevalence and associated features of autism spectrum disorder in extremely low gestational age newborns at age 10 years by Joseph, Robert M., O'Shea, Thomas M., Allred, Elizabeth N., Heeren, Tim, Hirtz, Deborah, Paneth, Nigel, Leviton, Alan, Kuban, Karl C. K.

“…We sought to estimate the prevalence of autism spectrum disorder (ASD) in children born extremely preterm relative to the U.S. population risk of 1.5% [CDC,…”
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Microbiologic and Histologic Characteristics of the Extremely Preterm Infant's Placenta Predict White Matter Damage and Later Cerebral Palsy. The ELGAN Study by Leviton, Alan, Allred, Elizabeth N, Kuban, Karl C K, Hecht, Jonathan L, Onderdonk, Andrew B, O'Shea, T Michael, Paneth, Nigel

“…Inflammatory phenomena seem to contribute to the occurrence of perinatal cerebral white matter damage and CP. The stimulus that initiates the inflammation…”
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Prenatal Metal Exposure Alters the Placental Proteome in a Sex-Dependent Manner in Extremely Low Gestational Age Newborns: Links to Gestational Age by Freedman, Anastasia N, Roell, Kyle, Engwall, Eiona, Bulka, Catherine, Kuban, Karl C K, Herring, Laura, Mills, Christina A, Parsons, Patrick J, Galusha, Aubrey, O'Shea, Thomas Michael, Fry, Rebecca C

“…Prenatal exposure to toxic metals is associated with altered placental function and adverse infant and child health outcomes. Adverse outcomes include those…”
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Socioeconomic status and early blood concentrations of inflammation-related and neurotrophic proteins among extremely preterm newborns by Leviton, Alan, Allred, Elizabeth N, Dammann, Olaf, Joseph, Robert M, Fichorova, Raina N, O'Shea, T Michael, Kuban, Karl C K

“…The main objective of this study was to evaluate the relationship between mother's socioeconomic disadvantage and blood concentrations of inflammation-related…”
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Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm by Santos, Jr, Hudson P, Bhattacharya, Arjun, Joseph, Robert M, Smeester, Lisa, Kuban, Karl C K, Marsit, Carmen J, O'Shea, T Michael, Fry, Rebecca C

“…Children born extremely preterm are at heightened risk for intellectual and social impairment, including Autism Spectrum Disorder (ASD). There is increasing…”
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Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes by Tomlinson, Martha Scott, Bommarito, Paige A, Martin, Elizabeth M, Smeester, Lisa, Fichorova, Raina N, Onderdonk, Andrew B, Kuban, Karl C K, O'Shea, T Michael, Fry, Rebecca C

“…Microorganisms in the placenta have been linked to adverse pregnancy outcomes as well as neonatal illness. Inflammation in the placenta has been identified as…”
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Genomic biomarkers of prenatal intrauterine inflammation in umbilical cord tissue predict later life neurological outcomes by Tilley, Sloane K, Joseph, Robert M, Kuban, Karl C K, Dammann, Olaf U, O'Shea, T Michael, Fry, Rebecca C

“…Preterm birth is a major risk factor for neurodevelopmental delays and disorders. This study aimed to identify genomic biomarkers of intrauterine inflammation…”
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Antenatal Antecedents of Cognitive Impairment at 24 Months In Extremely Low Gestational Age Newborns by HELDERMAN, Jennifer B, O'SHEA, Thomas M, KUBAN, Karl C. K, ALLRED, Elizabeth N, HECHT, Jonathan L, DAMMANN, Olaf, PANETH, Nigel, MCELRATH, T. F, ONDERDONK, Andrew, LEVITON, Alan

“…Extremely low gestational age neonates are more likely than term infants to develop cognitive impairment. Few studies have addressed antenatal risk factors of…”
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Elevated endogenous erythropoietin concentrations are associated with increased risk of brain damage in extremely preterm neonates by Korzeniewski, Steven J, Allred, Elizabeth, Logan, J Wells, Fichorova, Raina N, Engelke, Stephen, Kuban, Karl C K, O'Shea, T Michael, Paneth, Nigel, Holm, Mari, Dammann, Olaf, Leviton, Alan

“…We sought to determine, in very preterm infants, whether elevated perinatal erythropoietin (EPO) concentrations are associated with increased risks of…”
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Neonatal Cranial Ultrasound Lesions and Developmental Delays at 2 Years of Age Among Extremely Low Gestational Age Children by O'Shea, T. Michael, Kuban, Karl C. K, Allred, Elizabeth N, Paneth, Nigel, Pagano, Marcello, Dammann, Olaf, Bostic, Lisa, Brooklier, Kara, Butler, Samantha, Goldstein, Donald J, Hounshell, Gail, Keller, Cecelia, McQuiston, Susan, Miller, Alice, Pasternak, Steve, Plesha-Troyke, Susan, Price, Joan, Romano, Elaine, Solomon, Katherine M, Jacobson, Amanda, Westra, Sjirk, Leviton, Alan, Extremely Low Gestational Age Newborns Study Investigators

“…Studies of the relationship between ultrasound images from preterm newborns and developmental delay most often are based on small samples defined by birth…”
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Innovative computational approaches shed light on genetic mechanisms underlying cognitive impairment among children born extremely preterm by Liu, Weifang, Sun, Quan, Huang, Le, Bhattacharya, Arjun, Wang, Geoffery W, Tan, Xianming, Kuban, Karl C K, Joseph, Robert M, O'Shea, T Michael, Fry, Rebecca C, Li, Yun, Santos, Jr, Hudson P

“…Although survival rates for infants born extremely preterm (gestation < 28 weeks) have improved significantly in recent decades, neurodevelopmental impairment…”
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Early Blood Gas Abnormalities and the Preterm Brain by Leviton, Alan, Allred, Elizabeth, Kuban, Karl C. K., Dammann, Olaf, O'Shea, T. Michael, Hirtz, Deborah, Schreiber, Michael D., Paneth, Nigel

“…The authors explored associations between blood gas abnormalities in more than 1,000 preterm infants during the first postnatal days and indicators of neonatal…”
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Changes in Neurodevelopmental Outcomes From Age 2 to 10 Years for Children Born Extremely Preterm by Taylor, Genevieve L, Joseph, Robert M, Kuban, Karl C K, Douglass, Laurie M, Laux, Jeff, Andrews, Bree, Fry, Rebecca C, Price, Wayne A, O'Shea, Thomas M

“…Evidence-based care of extremely preterm infants (<28 weeks' gestation) depends heavily on research in which a primary outcome is infant neurodevelopmental…”
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Neurocognitive and Academic Outcomes at Age 10 Years of Extremely Preterm Newborns by Joseph, Robert M, O'Shea, Thomas M, Allred, Elizabeth N, Heeren, Tim, Hirtz, Deborah, Jara, Hernan, Leviton, Alan, Kuban, Karl C K

“…Despite reductions in mortality and morbidity among children born extremely preterm, they remain at high risk of neurocognitive deficits, with up to 40% having…”
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Cognitive Development and Quality of Life Associated With BPD in 10-Year-Olds Born Preterm by Sriram, Sudhir, Schreiber, Michael D, Msall, Michael E, Kuban, Karl C K, Joseph, Robert M, O' Shea, T Michael, Allred, Elizabeth N, Leviton, Alan

“…To compare neurocognitive, language, executive function, academic achievement, neurologic and behavioral outcomes, and quality of life at age 10 years in…”
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Neurodevelopment at Age 10 Years of Children Born <28 Weeks With Fetal Growth Restriction by Korzeniewski, Steven J, Allred, Elizabeth N, Joseph, Robert M, Heeren, Tim, Kuban, Karl C K, O'Shea, T Michael, Leviton, Alan

“…We sought to evaluate the relationships between fetal growth restriction (FGR) (both severe and less severe) and assessments of cognitive, academic, and…”
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Child and family factors associated with positive outcomes among youth born extremely preterm by Emmanuel, Crisma, Yi, Joe X., Joseph, Robert M., Kuban, Karl K. C., Knafl, Kathy A., Docherty, Sharron L., Hodges, Eric A., Fry, Rebecca C., O’Shea, T. Michael, Santos, Hudson P.

“…Background To analyze the relationship of child behavioral and communication disorders, and adverse family events, to later-in-life child health and…”
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Neurodevelopment of Extremely Preterm Infants who had Necrotizing Enterocolitis with or without Late Bacteremia by Martin, Camilia R., MD, MS, Dammann, Olaf, MD, Allred, Elizabeth N., MS, Patel, Sonal, MD, O'Shea, T. Michael, MD, MPH, Kuban, Karl C.K., MD, SMEpi, Leviton, Alan, MD

“…Objective To evaluate neurodevelopment after necrotizing enterocolitis (NEC) and late bacteremia, alone and together. Study design Sample included 1155 infants…”
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