Search Results - "KRUTZSCH, H"

Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats by IRUELA-ARISPE, M. L, LOMBARDO, M, KRUTZSCH, H. C, LAWLER, J, ROBERTS, D. D

“…Suppression of tumor growth by thrombospondin-1 (TSP-1) has been associated with its ability to inhibit neovascularization. The antiangiogenic activity of…”
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Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells by GUO, N.-H, KRUTZSCH, H. C, INMAN, J. K, ROBERTS, D. D

“…Thrombospondin 1 (TSP1) inhibits angiogenesis and modulates endothelial cell adhesion, motility, and growth. The antiproliferative activity of TSP1 is mimicked…”
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Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family by STETLER-STEVENSON, W. G, KRUTZSCH, H. C, LIOTTA, L. A

“…Human melanoma cells secret a 21-kDa protein, termed CSC-21K, which binds with 1:1 molar stoichiometry to the matrix metalloproteinase type IV collagenase…”
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Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein by Stracke, M L, Krutzsch, H C, Unsworth, E J, Arestad, A, Cioce, V, Schiffmann, E, Liotta, L A

“…Autotaxin (ATX) is a potent human motility-stimulating protein that has been identified in the conditioned medium from A2058 melanoma cells. This protein has…”
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Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro by Takimoto, M., Tomonaga, T., Matunis, M., Avigan, M., Krutzsch, H., Dreyfuss, G., Levens, D.

“…A homopurine/homopyrimidine-like sequence is found 100-150 base pairs upstream of the human c-myc promoter P1. This element, termed the CT-element, has been…”
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On an experimentally observed phenomenon on vortex rings during their translational movement in a real liquid by Krutzsch, C.-H., Bolster, D., Hershberger, R., Donnelly, R.J.

“…In an investigation on vortex rings suggested to the author by Prof.~Tomaschek, he succeeded in observing a novel phenomenon, namely the appearance of waves on…”
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A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif by DUNCAN, R, BAZAR, L, MICHELOTTI, G, TOMONAGA, T, KRUTZSCH, H, AVIGAN, M, LEVENS, D

“…The far upstream element (FUSE) of the human c-myc proto-oncogene stimulates expression in undifferentiated cells. A FUSE-binding protein (FBP) is present in…”
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The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation by STETLER-STEVENSON, W. G, KRUTZSCH, H. C, WACHER, M. P, MARGULIES, I. M. K, LIOTTA, L. A

“…Type IV collagenase is a metalloproteinase which cleaves type IV collagen in a pepsin-resistant domain. Organomercurial activation of the latent 70-kDa type IV…”
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Inhibition of Retinal Angiogenesis by Peptides Derived from Thrombospondin-1 by Shafiee, Afshin, Penn, John S, Krutzsch, Henry C, Inman, John K, Roberts, David D, Blake, Diane A

“…Thrombospondin (TSP)1 is a tumor suppressor with activity that is associated with its ability to inhibit neovascularization. Previous studies have mapped this…”
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cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases by Murata, J, Lee, H Y, Clair, T, Krutzsch, H C, Arestad, A A, Sobel, M E, Liotta, L A, Stracke, M L

“…A human cDNA clone encoding autotaxin, a tumor cell motility-stimulating protein, reveals that this protein is an ecto/exo-enzyme with significant homology to…”
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Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development by Rosengard, Ariella M, Krutzsch, Henry C, Shearn, Allen, Biggs, Joseph R, Barker, Edward, Margulies, Inger M. K, King, C. Richter, Liotta, Lance A, Steeg, Patricia S

“…Tumour metastasis is the principal cause of death for cancer patients. We have identified the nm23 gene, for which RNA levels are reduced in tumour cells of…”
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Regulation of Transforming Growth Factor-β Activation by Discrete Sequences of Thrombospondin 1 (∗) by Schultz-Cherry, Stacey, Chen, Hui, Mosher, Deane F., Misenheimer, Tina M., Krutzsch, Henry C., Roberts, David D., Murphy-Ullrich, Joanne E.

“…Transforming growth factor-β (TGF-β) is a potent growth regulatory protein secreted by virtually all cells in a latent form. A major mechanism of regulating…”
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Structural Requirements for Hemoglobin To Induce Fibronectin Receptor Expression in Candida albicans by Pendrak, Michael L, Krutzsch, Henry C, Roberts, David D

“…Hemoglobin (Hb) is a host factor that induces expression of a promiscuous receptor on Candida albicans for fibronectin (FN) and several other extracellular…”
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Nuclear/cytoplasmic localization of the multiple endocrine neoplasia type 1 gene product, menin by Huang, S C, Zhuang, Z, Weil, R J, Pack, S, Wang, C, Krutzsch, H C, Pham, T A, Lubensky, I A

“…Although the gene responsible for multiple endocrine neoplasia, type 1 (MEN1) has been identified recently, the function of its gene product, menin, is not…”
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The purification and characterization of an extremely thermostable alpha-amylase from the hyperthermophilic archaebacterium Pyrococcus furiosus by Laderman, K A, Davis, B R, Krutzsch, H C, Lewis, M S, Griko, Y V, Privalov, P L, Anfinsen, C B

“…The alpha-amylase from Pyrococcus furiosus, a hyperthermophilic archaebacterium, has been purified to homogeneity. The enzyme is a homodimer with a subunit…”
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Signal Transduction for Chemotaxis and Haptotaxis by Matrix Molecules in Tumor Cells by Aznavoorian, Sadie, Stracke, Mary L., Krutzsch, Henry, Schiffmann, Elliott, Liotta, Lance A.

“…Transduction of signals initiating motility by extracellular matrix (ECM) molecules differed depending on the type of matrix molecule and whether the ligand…”
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Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type I repeats of thrombospondin by Vogel, T, Guo, N H, Krutzsch, H C, Blake, D A, Hartman, J, Mendelovitz, S, Panet, A, Roberts, D D

“…Thrombospondin is an inhibitor of angiogenesis that modulates endothelial cell adhesion, proliferation, and motility. Synthetic peptides from the second type I…”
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Treatment of Experimental Brain Tumors with Trombospondin-1 Derived Peptides: an In Vivo Imaging Study by Bogdanov, A., Marecos, E., Cheng, H.C., Chandrasekaran, L., Krutzsch, H.C., Roberts, D.D., Weissleder, R.

“…Antiangiogenic and antiproliferative effects of synthetic D-reverse peptides derived from the type 1 repeats of thrombospondin (TSP1) [1,2] were studied in…”
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Heparin-binding peptides from the type I repeats of thrombospondin. Structural requirements for heparin binding and promotion of melanoma cell adhesion and chemotaxis by NENG-HUA GUO, KRUTZSCH, H. C, NEGRE, E, ZABRENETZKY, V. S, ROBERTS, D. D

“…Synthetic peptides derived from the type I repeats of human platelet thrombospondin containing a consensus sequence Trp-Ser-Xaa-Trp bind to heparin, promote…”
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Apolipoprotein E: a potent inhibitor of endothelial and tumor cell proliferation by Vogel, T, Guo, N H, Guy, R, Drezlich, N, Krutzsch, H C, Blake, D A, Panet, A, Roberts, D D

“…Recombinant human apolipoprotein E3 (apoE), purified from E. coli, inhibited the proliferation of several cell types, including endothelial cells and tumor…”
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