Search Results - "KRUTH, H"

Accumulation of Cholesterol with Age in Human Bruch's Membrane by Curcio, Christine A, Millican, C. Leigh, Bailey, Tammy, Kruth, Howard S

“…To determine the cholesterol composition of normal human Bruch's membrane and choroid as a function of age and retinal location. Human eyes with grossly normal…”
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Ag/Na ion exchange in soda-lime glasses and the formation of small Ag nanoparticles by Dubiel, M., Haug, J., Kruth, H., Hofmeister, H., Schicke, K.-D.

“…We investigated the formation of very small Ag nanoparticles of 1–2 nm size in soda-lime glass with enhanced amounts of iron oxide by Ag/Na ion exchange…”
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Thermal expansion and interatomic potentials of silver revealed by extended x-ray absorption fine structure spectroscopy using high-order perturbation theory by Haug, J., Chassé, A., Schneider, R., Kruth, H., Dubiel, M.

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Macrophage Foam Cell Formation with Native Low Density Lipoprotein by Kruth, Howard S., Huang, Wei, Ishii, Itsuko, Zhang, Wei-Yang

“…This investigation has elucidated a mechanism for development of macrophage foam cells when macrophages are incubated with native low density lipoprotein…”
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Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I-transgenic rabbits by DUVERGER, N, KRUTH, H, DENEFLE, P, EMMANUEL, F, CAILLAUD, J.-M, VIGLIETTA, C, CASTRO, G, TAILLEUX, A, FIEVET, C, FRUCHART, J. C, HOUDEBINE, L. M

“…Prospective epidemiological studies support the hypothesis that high levels of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I limit…”
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Structure and properties of liquid crystalline phases formed by achiral banana-shaped molecules by Diele, S., Grande, S., Kruth, H., Lischka, CH, Pelzl, G., Weissflog, W., Wirth, I.

“…Two new banana-shaped mesogens have been prepared and their mesophases have been studied. As indicated by calorimetry and polarizing microscopy both compounds…”
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Prevention of bioprosthetic heart valve calcification by ethanol preincubation. Efficacy and mechanisms by Vyavahare, N, Hirsch, D, Lerner, E, Baskin, J Z, Schoen, F J, Bianco, R, Kruth, H S, Zand, R, Levy, R J

“…Calcification of the cusps of bioprosthetic heart valves fabricated from either glutaraldehyde cross-linked porcine aortic valves or bovine pericardium…”
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A defect in cholesterol esterification in Niemann-Pick disease (type C) patients by Pentchev, Peter G., Comly, Marcella E., Kruth, Howard S., Vanier, Marie T., Wenger, David A., Patel, Shutish, Brady, Roscoe O.

“…The demonstration of a defect of cholesterol esterification in a mutant strain of BALB/c mice with an attendant reduction of sphingomyelinase activity…”
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Plasmin-mediated Macrophage Reversal of Low Density Lipoprotein Aggregation by Zhang, Wei-Yang, Ishii, Itsuko, Kruth, Howard S.

“…Evidence suggests that aggregated low density lipoprotein (AgLDL) accumulates in atherosclerotic lesions. Previously, we showed that AgLDL induces and enters…”
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Type-C Niemann-Pick Disease: Low Density Lipoprotein Uptake is Associated with Premature Cholesterol Accumulation in the Golgi Complex and Excessive Cholesterol Storage in Lysosomes by Blanchette-Mackie, E. Joan, Dwyer, Nancy K., Amende, Lynn M., Kruth, Howard S., Butler, Jean D., Sokol, Jacob, Comly, Marcella E., Vanier, Marie T., August, J. Thomas, Brady, Roscoe O., Pentchev, Peter G.

“…Incubation of fibroblasts derived from patients with type-C Niemann-Pick disease with low density lipoprotein results in excessive intracellular accumulation…”
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Detection of cholesterol associated with calcium mineral using confocal fluorescence microscopy by Sarig, S, Weiss, T A, Katz, I, Kahana, F, Azoury, R, Okon, E, Kruth, H S

“…Cholesterol and calcium are prominant components within human atherosclerotic lesions. Both accumulate predominantly within the central core region of lesions…”
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Production of cholesterol-enriched nascent high density lipoproteins by human monocyte-derived macrophages is a mechanism that contributes to macrophage cholesterol efflux by Kruth, H S, Skarlatos, S I, Gaynor, P M, Gamble, W

“…Atherosclerotic lesions have a lipid core containing crystals and liposomes enriched in unesterified cholesterol as well as numerous monocyte-macrophages…”
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Macrophage foam cells and atherosclerosis by Kruth, H S

“…Focal buildup of cholesterol in arteries is the process that produces atherosclerotic plaques, the cause of most coronary artery disease and strokes…”
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Localization of unesterified cholesterol in human atherosclerotic lesions. Demonstration of filipin-positive, oil-red-O-negative particles by Kruth, HS

“…Both unesterified and esterified cholesterol accumulate in human atherosclerotic lesions. Whereas previous studies have established that esterified cholesterol…”
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The fate of lipoprotein cholesterol entering the arterial wall by Kruth, H S

“…Recent findings have helped to explain the fate of cholesterol entering the arterial wall. LDL can undergo both fusion and aggregation. These changes may cause…”
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Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol by Sokol, J, Blanchette-Mackie, J, Kruth, H S, Dwyer, N K, Amende, L M, Butler, J D, Robinson, E, Patel, S, Brady, R O, Comly, M E

“…The intracellular accumulation of unesterified cholesterol was examined during 24 h of low density lipoprotein (LDL) uptake in normal and Niemann-Pick C…”
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Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts by Pentchev, P G, Comly, M E, Kruth, H S, Tokoro, T, Butler, J, Sokol, J, Filling-Katz, M, Quirk, J M, Marshall, D C, Patel, S

“…Incubation of mutant Niemann-Pick C fibroblasts with low-density lipoprotein (LDL) resulted in excessive internalization of lipoprotein and extensive cellular…”
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Dominant late-onset retinal degeneration with regional variation of sub-retinal pigment epithelium deposits, retinal function, and photoreceptor degeneration by Milam, A H, Curcio, C A, Cideciyan, A V, Saxena, S, John, S K, Kruth, H S, Malek, G, Heckenlively, J R, Weleber, R G, Jacobson, S G

“…To clarify the pathogenesis of late-onset retinal degeneration (L-ORD), an autosomal dominant disorder characterized by thick deposits of lipid-rich material…”
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Apolipoprotein E Produced by Human Monocyte-derived Macrophages Mediates Cholesterol Efflux That Occurs in the Absence of Added Cholesterol Acceptors by Zhang, Wei-Yang, Gaynor, Paulette M., Kruth, Howard S.

“…Human monocyte-derived macrophages can efflux accumulated cholesterol without exogenously added cholesterol acceptors (Kruth, H. S., Skarlatos, S. I., Gaynor,…”
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Cholesterol deposition in atherosclerotic lesions by Kruth, H S

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