Search Results - "KRUPP, L. B"

Study and treatment of post Lyme disease (STOP-LD): A randomized double masked clinical trial by KRUPP, L. B, HYMAN, L. G, GRIMSON, R, COYLE, P. K, MELVILLE, P, AHNN, S, DATTWYLER, R, CHANDLER, B

“…To determine whether post Lyme syndrome (PLS) is antibiotic responsive. The authors conducted a single-center randomized double-masked placebo-controlled trial…”
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Dose comparison trial of sustained-release fampridine in multiple sclerosis by GOODMAN, A. D, BROWN, T. R, COHEN, J. A, KRUPP, L. B, SCHAPIRO, R, SCHWID, S. R, COHEN, R, MARINUCCI, L. N, BLIGHT, A. R

“…To examine the efficacy and safety of three different doses of sustained-release fampridine in people with multiple sclerosis (MS). This multicenter,…”
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Social cognition in pediatric-onset multiple sclerosis (MS) by Charvet, LE, Cleary, RE, Vazquez, K, Belman, AL, Krupp, LB

“…Background: Pediatric-onset multiple sclerosis (MS) patients represent a subpopulation who are diagnosed during the course of development. Social cognitive…”
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Donepezil improved memory in multiple sclerosis in a randomized clinical trial by KRUPP, L. B, CHRISTODOULOU, C, MELVILLE, P, SCHERL, W. F, MACALLISTER, W. S, ELKINS, L. E

“…To determine the effect of donepezil in treating memory and cognitive dysfunction in multiple sclerosis (MS). This single-center double-blind…”
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Younger children with MS have a distinct CSF inflammatory profile at disease onset by CHABAS, D, NESS, J, RODRIGUEZ, M, WEINSTOCK-GUTTMAN, B, KRUPP, L. B, WAUBANT, E, BELMAN, A, YEH, E. A, KUNTZ, N, GORMAN, M. P, STROBER, J. B, DE KOUCHKOVSKY, I, MCCULLOCH, C, CHITNIS, T

“…The clinical and MRI presentation differs between earlier- and later-onset pediatric multiple sclerosis (MS), whereas the effect of age on the CSF inflammatory…”
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Multicenter randomized clinical trial of donepezil for memory impairment in multiple sclerosis by KRUPP, L. B, CHRISTODOULOU, C, SCHWID, S. R, WEINSTOCK-GUTTMAN, B, WESTERVELT, H. J, WISHART, H, MELVILLE, P, SCHERL, W. F, PAI, L.-Y, MUENZ, L. R, HE, D, BENEDICT, R. H. B, GOODMAN, A, RIZVI, S

“…The goal of this study was to determine if memory would be improved by donepezil as compared to placebo in a multicenter, double-blind, randomized clinical…”
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Cognitive functioning in children and adolescents with multiple sclerosis by MACALLISTER, W. S, BELMAN, A. L, MILAZZO, M, WEISBROT, D. M, CHRISTODOULOU, C, SCHERL, W. F, PRESTON, T. E, CIANCIULLI, C, KRUPP, L. B

“…To examine cognitive functioning in children with multiple sclerosis (MS). The authors examined the neuropsychological profile of 37 children with a diagnosis…”
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Longitudinal correlates of fatigue in multiple sclerosis by Patrick, E, Christodoulou, C, Krupp, LB

“…Objective To determine the predictors of longitudinal changes in fatigue based on pain, mood, and neurological impairment across multiple sclerosis (MS)…”
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Longitudinal evaluation of cognitive functioning in pediatric multiple sclerosis: report from the US Pediatric Multiple Sclerosis Network by Charvet, LE, O’Donnell, EH, Belman, AL, Chitnis, T, Ness, JM, Parrish, J, Patterson, M, Rodriguez, M, Waubant, E, Weinstock-Guttman, B, Krupp, LB

“…Background: Approximately one-third of those with pediatric-onset multiple sclerosis (MS) experience cognitive impairment. Less is known concerning their…”
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Protein expression profiles in pediatric multiple sclerosis: potential biomarkers by Rithidech, KN, Honikel, L, Milazzo, M, Madigan, D, Troxell, R, Krupp, LB

“…The diagnosis of pediatric multiple sclerosis (MS) is challenging due to its low frequency and the overlap with other acquired childhood demyelinating…”
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Cognitive performance and MR markers of cerebral injury in cognitively impaired MS patients by Christodoulou, C, Krupp, L B, Liang, Z, Huang, W, Melville, P, Roque, C, Scherl, W F, Morgan, T, MacAllister, W S, Li, L, Tudorica, L A, Li, X, Roche, P, Peyster, R

“…To relate neuropsychological performance to measures of cerebral injury in persons with MS selected for cognitive impairment. Participants were 37 individuals…”
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Visual-cognitive processing deficits in pediatric multiple sclerosis by Smerbeck, AM, Parrish, J, Serafin, D, Yeh, EA, Weinstock-Guttman, B, Hoogs, M, Krupp, LB, Benedict, RHB

“…Background: Children with multiple sclerosis (MS) can suffer significant cognitive deficits. This study investigates the sensitivity and validity in pediatric…”
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Copy number variation in pediatric multiple sclerosis by McElroy, JP, Krupp, LB, Johnson, BA, McCauley, JL, Qi, Z, Caillier, SJ, Gourraud, PA, Yu, J, Nathanson, L, Belman, AL, Hauser, SL, Waubant, E, Hedges, DJ, Oksenberg, JR

“…Background: Pediatric onset multiple sclerosis (MS) accounts for 2-4% of all MS. It is unknown whether the disease shares the same underlying pathophysiology…”
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Fatigue therapy in multiple sclerosis : results of a double-blind, randomized, parallel trial of amantadine, pemoline, and placebo by KRUPP, L. B, COYLE, P. K, DOSCHER, C, MILLER, A, CROSS, A. H, JANDORF, L, HALPER, J, JOHNSON, B, MORGANTE, L, GRIMSON, R

“…To determine the relative efficacy of amantadine, pemoline, and placebo in treatment of multiple sclerosis (MS)-related fatigue. Fatigue is a complication of…”
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Remotely-delivered cognitive remediation in multiple sclerosis (MS): protocol and results from a pilot study by Charvet, LE, Shaw, MT, Haider, L, Melville, P, Krupp, LB

“…Background Cognitive impairment represents a critical unmet treatment need in multiple sclerosis (MS). Cognitive remediation is promising but traditionally…”
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The measurement of fatigue: a new instrument by Schwartz, J E, Jandorf, L, Krupp, L B

“…Fatigue is a frequent medical symptom which has not been routinely measured. We present a 29-item fatigue assessment instrument, describe its psychometric…”
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Are quantitative functional measures more sensitive to worsening MS than traditional measures? by SCHWID, S. R, GOODMAN, A. D, APATOFF, B. R, COYLE, P. K, JACOBS, L. D, KRUPP, L. B, MILLER, A. E, WENDE, K. E, BROWNSCHEIDLE, C. M

“…The authors used data collected prospectively during a multicenter trial in 133 patients with secondary progressive MS to assess the relative sensitivity of…”
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A study of fatigue in systemic lupus erythematosus by Krupp, L B, LaRocca, N G, Muir, J, Steinberg, A D

“…Fifty-nine patients with systemic lupus erythematosus were evaluated by questionnaires, histories, physical examinations and routine laboratory studies in…”
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The psychosocial consequences of pediatric multiple sclerosis by MacAllister, W S, Boyd, J R, Holland, N J, Milazzo, M C, Krupp, L B

“…Although psychological distress and cognitive dysfunction are well documented in adults with multiple sclerosis (MS), they are poorly understood in children…”
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Metabolic differences between multiple sclerosis subtypes measured by quantitative MR spectroscopy by Pan, J W, Coyle, P K, Bashir, K, Whitaker, J N, Krupp, L B, Hetherington, H P

“…We used quantitative magnetic resonance (MR) spectroscopic imaging with T1-based image segmentation to evaluate the subtypes of multiple sclerosis (MS) (eight…”
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