Search Results - "KRUG, T"

Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection by Shapiro, Maxwell, Krug, Laurie T, MacCarthy, Thomas

“…Herpes-Simplex Virus 1 (HSV-1) infects most humans when they are young, sometimes with fatal consequences. Gene expression occurs in a temporal order upon…”
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A role of hypoxia-inducible factor 1 alpha in Murine Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency by López-Rodríguez, Darlah M, Kirillov, Varvara, Krug, Laurie T, Mesri, Enrique A, Andreansky, Samita

“…The hypoxia-inducible factor 1 alpha (HIF1α) protein and the hypoxic microenvironment are critical for infection and pathogenesis by the oncogenic…”
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Sequencing of Kaposi's Sarcoma Herpesvirus (KSHV) genomes from persons of diverse ethnicities and provenances with KSHV-associated diseases demonstrate multiple infections, novel polymorphisms, and low intra-host variance by Marshall, Vickie A, Cornejo Castro, Elena M, Goodman, Charles A, Labo, Nazzarena, Liu, Isabella, Fisher, Nicholas C, Moore, Kyle N, Nair, Ananthakrishnan, Immonen, Taina, Keele, Brandon F, Polizzotto, Mark N, Uldrick, Thomas S, Mu, Yunxiang, Saswat, Tanuja, Krug, Laurie T, McBride, Kevin M, Lurain, Kathryn, Ramaswami, Ramya, Yarchoan, Robert, Whitby, Denise

“…Recently published near full-length KSHV genomes from a Cameroon Kaposi sarcoma case-control study showed strong evidence of viral recombination and mixed…”
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RNA-guided gene editing of the murine gammaherpesvirus 68 genome reduces infectious virus production by Foreman, Hui-Chen Chang, Kirillov, Varvara, Paniccia, Gabrielle, Catalano, Demetra, Andrunik, Trevor, Gupta, Swati, Krug, Laurie T, Zhang, Yue

“…Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV) are cancer-causing viruses that establish lifelong infections in humans. Gene editing using the…”
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Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesis by Ramaswami, Ramya, Tagawa, Takanobu, Mahesh, Guruswamy, Serquina, Anna, Koparde, Vishal, Lurain, Kathryn, Dremel, Sarah, Li, Xiaofan, Mungale, Ameera, Beran, Alex, Ohler, Zoe Weaver, Bassel, Laura, Warner, Andrew, Mangusan, Ralph, Widell, Anaida, Ekwede, Irene, Krug, Laurie T, Uldrick, Thomas S, Yarchoan, Robert, Ziegelbauer, Joseph M

“…Abstract Background Kaposi sarcoma (KS) is a multicentric tumor caused by Kaposi sarcoma herpesvirus (KSHV) that leads to morbidity and mortality among people…”
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Dangerous Liaisons: Gammaherpesvirus Subversion of the Immunoglobulin Repertoire by Zelazowska, Monika A, McBride, Kevin, Krug, Laurie T

“…A common biologic property of the gammaherpesviruses Epstein-Barr Virus and Kaposi sarcoma herpesvirus is their use of B lymphocytes as a reservoir of latency…”
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Gammaherpesviral gene expression and virion composition are broadly controlled by accelerated mRNA degradation by Abernathy, Emma, Clyde, Karen, Yeasmin, Rukhsana, Krug, Laurie T, Burlingame, Al, Coscoy, Laurent, Glaunsinger, Britt

“…Lytic gammaherpesvirus infection restricts host gene expression by promoting widespread degradation of cytoplasmic mRNA through the activity of the viral…”
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Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models by Hogan, Chad H, Owens, Shana M, Reynoso, Glennys V, Liao, Yifei, Meyer, Thomas J, Zelazowska, Monika A, Liu, Bin, Li, Xiaofan, Grosskopf, Anna K, Khairallah, Camille, Kirillov, Varvara, Reich, Nancy C, Sheridan, Brian S, McBride, Kevin M, Gewurz, Benjamin E, Hickman, Heather D, Forrest, J Craig, Krug, Laurie T

“…Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of…”
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KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine by Casper, Corey, Corey, Lawrence, Cohen, Jeffrey I., Damania, Blossom, Gershon, Anne A., Kaslow, David C., Krug, Laurie T., Martin, Jeffrey, Mbulaiteye, Sam M., Mocarski, Edward S., Moore, Patrick S., Ogembo, Javier Gordon, Phipps, Warren, Whitby, Denise, Wood, Charles

“…Seven viruses cause at least 15% of the total cancer burden. Viral cancers have been described as the “low-hanging fruit” that can be potentially prevented or…”
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Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host by Cieniewicz, Brandon, Santana, Alexis L, Minkah, Nana, Krug, Laurie T

“…Herpesviruses establish a chronic infection in the host characterized by intervals of lytic replication, quiescent latency, and reactivation from latency…”
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A codon-shuffling method to prevent reversion during production of replication-defective herpesvirus stocks: Implications for herpesvirus vaccines by Li, Gang, Ward, Charles, Yeasmin, Rukhsana, Skiena, Steven, Krug, Laurie T., Forrest, J. Craig

“…Herpesviruses establish life-long chronic infections that place infected hosts at risk for severe disease. Herpesvirus genomes readily undergo homologous…”
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Enhanced response of T cells from murine gammaherpesvirus 68-infected mice lacking the suppressor of T cell receptor signaling molecules Sts-1 and Sts-2 by Cieniewicz, Brandon, Carpino, Nicholas, Krug, Laurie T

“…The human gammaherpesviruses establish life-long infections that are associated with the development of lymphomas and neoplasms, especially in…”
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Deposition rate characteristics for steady state high power impulse magnetron sputtering (HIPIMS) discharges generated with a modulated pulsed power (MPP) generator by Papa, F., Gerdes, H., Bandorf, R., Ehiasarian, A.P., Kolev, I., Braeuer, G., Tietema, R., Krug, T.

“…High power impulse magnetron sputtering (HIPIMS) pulses have been of great interest over the last decade. With such sputtering techniques a substantial amount…”
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Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues by Smith, Kyle R, Paul, Somnath, Dong, Qiwen, Anannya, Orchi, Oldenburg, Darby G, Forrest, J Craig, McBride, Kevin M, Krug, Laurie T

“…Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA…”
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Efficient Raman Enhancement and Intermittent Light Emission Observed in Single Gold Nanocrystals by Krug, John T, Wang, Geoffrey D, Emory, Steven R, Nie, Shuming

“…This paper reports two fundamental observations on the size-dependent optical properties of colloidal gold nanoparticles. First, faceted gold nanocrystals in…”
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Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in the Viral Genome by Dong, Qiwen, Smith, Kyle R, Oldenburg, Darby G, Shapiro, Maxwell, Schutt, William R, Malik, Laraib, Plummer, Joshua B, Mu, Yunxiang, MacCarthy, Thomas, White, Douglas W, McBride, Kevin M, Krug, Laurie T

“…Misincorporation of uracil or spontaneous cytidine deamination is a common mutagenic insult to DNA. Herpesviruses encode a viral uracil-DNA glycosylase (vUNG)…”
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A replication-deficient gammaherpesvirus vaccine protects mice from lytic disease and reduces latency establishment by Bland, Wesley A., Mitra, Dipanwita, Owens, Shana, McEvoy, Kyle, Hogan, Chad H., Boccuzzi, Luciarita, Kirillov, Varvara, Meyer, Thomas J., Khairallah, Camille, Sheridan, Brian S., Forrest, J. Craig, Krug, Laurie T.

“…Gammaherpesviruses are oncogenic viruses that establish lifelong infections and are significant causes of morbidity and mortality. Vaccine strategies to limit…”
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Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice by Van Skike, Nick D, Minkah, Nana K, Hogan, Chad H, Wu, Gary, Benziger, Peter T, Oldenburg, Darby G, Kara, Mehmet, Kim-Holzapfel, Deborah M, White, Douglas W, Tibbetts, Scott A, French, Jarrod B, Krug, Laurie T

“…Gammaherpesviruses encode proteins with homology to the cellular purine metabolic enzyme formyl-glycinamide-phosphoribosyl-amidotransferase (FGARAT), but the…”
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Tiled Microarray Identification of Novel Viral Transcript Structures and Distinct Transcriptional Profiles during Two Modes of Productive Murine Gammaherpesvirus 68 Infection by YEE HIN CHENG, Benson, ZHI, Jizu, SANTANA, Alexis, KHAN, Sohail, SALINAS, Eduardo, CRAIG FORREST, J, YUETING ZHENG, JAGGI, Shirin, LEATHERWOOD, Janet, KRUG, Laurie T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis by Torres-González, Edilson, Bueno, Marta, Tanaka, Atsuko, Krug, Laurie T, Cheng, Dong-Sheng, Polosukhin, Vasiliy V, Sorescu, Dan, Lawson, William E, Blackwell, Timothy S, Rojas, Mauricio, Mora, Ana L

“…The incidence of idiopathic pulmonary fibrosis (IPF) increases with age. The mechanisms that underlie the age-dependent risk for IPF are unknown. Based on…”
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