Search Results - "KROSHUS, Timothy J"

Risk factors for the development of bronchiolitis obliterans syndrome after lung transplantation by Kroshus, Timothy J., Kshettry, Vibhu R., Savik, Kay, John, Ranjit, Hertz, Marshall I., Bolman, R.Morton

“…Objective: This study identifies specific clinical and immunologic factors in lung transplant recipients that influence the subsequent development of chronic…”
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Multidisciplinary Standardized Care for Acute Aortic Dissection: Design and Initial Outcomes of a Regional Care Model by HARRIS, Kevin M, STRAUSS, Craig E, ROHMAN, Eric, ORLANDI, Quirino G, FLAVIN, Thomas F, KSHETTRY, Vibhu R, GRAHAM, Kevin J, HIRSCH, Alan T, HENRY, Timothy D, DUVAL, Sue, UNGER, Barbara T, KROSHUS, Timothy J, INAMPUDI, Subbarao, COHEN, Jonathan D, KAPSNER, Christopher, BOLAND, Lori L, EALES, Frazier

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Manufacturer-provided effective orifice area index charts and the prevention of prosthesis-patient mismatch by House, Chad M, Nelson, William B, Kroshus, Timothy J, Dahiya, Ranjan, Pibarot, Philippe

“…Prosthesis-patient mismatch (PPM) occurs when an implanted prosthesis is too small relative to the patient's body surface area (BSA). However, mismatch can…”
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Primary pulmonary hypertension as a risk factor for the development of obliterative bronchiolitis in lung allograft recipients by Kshettry, V R, Kroshus, T J, Savik, K, Hertz, M I, Bolman, R M

“…Obliterative bronchiolitis (OB) is a major factor limiting long-term survival after lung transplantation. The etiology of this disease process remains…”
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Unilateral volume reduction after single-lung transplantation for emphysema by Kroshus, Timothy J., Bolman, R. Morton, Kshettry, Vibhu R.

“…Single-lung transplantation has become accepted therapy for patients with end-stage emphysema. Hyperinflation of the native lung can occur after single-lung…”
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THE FREQUENCY, ETIOLOGY AND OUTCOME OF ST-ELEVATION MYOCARDIAL INFARCTION PATIENTS REQUIRING URGENT CORONARY ARTERY BYPASS GRAFT by Tschautscher, Craig, Larson, David M, Henry, Timothy D, Henry, Jason T, Ross, Monique G, Schwartz, Robert S, Sharkey, Scott W, Kroshus, Timothy J

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Early and Late Airway Complications After Lung Transplantation: Incidence and Management by Kshettry, Vibhu R, Kroshus, Timothy J, Hertz, Marshall I, Hunter, David W, Shumway, Sara J, Bolman, R.Morton

“…Background. Airway anastomosis complications continue to be a source of morbidity for lung transplant recipients. Methods. This study analyzes incidence,…”
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Deep venous thrombosis and pulmonary embolism after lung transplantation by Kroshus, Timothy J., Kshettry, Vibhu R., Hertz, Marshall I., Bolman, R.Morton

“…The incidence of deep venous thrombosis or pulmonary embolism after lung or heart-lung transplantation has not been well defined. Pulmonary embolism may be of…”
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Decision-making in the choice of heart valve for replacement in patients aged 60-70 years: twenty-year follow up of the St. Jude Medical aortic valve prosthesis by Emery, Robert W, Arom, Kit V, Kshettry, Vibhu R, Kroshus, Timothy J, Von, RuedenThomasJ, Kersten, Thomas E, Lillehei, Theodore J, Nicoloff, Demetre M, Erickson, Carla A

“…The choice of a cardiac valve for patients with aortic valvular pathology remains controversial. Younger patients may be at risk for long-term complications…”
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Suicide right ventricle after lung transplantation for Eisenmenger syndrome by Kroshus, Timothy J., Kshettry, Vibhu R., Hertz, Marshall I., Everett, Jeffrey E., Bolman, R. Morton

“…Right ventricular outflow tract obstruction, or “suicide right ventricle,” rarely has been observed after single or bilateral single-lung transplantation for…”
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Expression of human CD59 in transgenic pig organs enhances organ survival in an ex vivo xenogeneic perfusion model by KROSHUS, T. J, BOLMAN, R. M, DALMASSO, A. P, ROLLINS, S. A, GUILMETTE, E. R, WILLIAMS, B. L, SQUINTO, S. P, FODOR, W. L

“…The serious shortage of available donor organs for patients with end stage organ failure who are in need of solid organ transplantation has led to a heightened…”
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Selective IgM depletion prolongs organ survival in an ex vivo model of pig-to-human xenotransplantation by KROSHUS, T. J, BOLMAN, R. M, DALMASSO, A. P

“…In the pig-to-primate model, xenograft hyperacute rejection (HAR) is mediated by antibody and complement. Previous studies have implicated xenoreactive IgM…”
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Complement inhibition with an anti-C5 monoclonal antibody prevents acute cardiac tissue injury in an ex vivo model of pig-to-human xenotransplantation by Kroshus, T J, Rollins, S A, Dalmasso, A P, Elliott, E A, Matis, L A, Squinto, S P, Bolman, 3rd, R M

“…Prevention of hyperacute xenograft rejection in the pig-to-primate combination has been accomplished by removal of natural antibodies, complement depletion…”
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A recombinant soluble chimeric complement inhibitor composed of human CD46 and CD55 reduces acute cardiac tissue injury in models of pig-to-human heart transplantation by KROSHUS, T. J, SALERNO, C. T, YEH, C. G, HIGGINS, P. J, BOLMAN, R. M, DALMASSO, A. P

“…Inasmuch as complement plays a critical role in many pathological processes and in xenograft rejection, efficient complement inhibitors are of great interest…”
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A RECOMBINANT SOLUBLE CHIMERIC COMPLEMENT INHIBITOR COMPOSED OF HUMAN CD46 AND CD55 REDUCES ACUTE CARDIAC TISSUE INJURY IN MODELS OF PIG-TO-HUMAN HEART TRANSPLANTATION1, 2 by Kroshus, Timothy J., Salerno, Christopher T., Yeh, C. Grace, Higgins, Paul J., Bolman, R. Morton, Dalmasso, Agustin P.

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SELECTIVE IgM DEPLETION PROLONGS ORGAN SURVIVAL IN AN EX VIVO MODEL OF PIG-TO-HUMAN XENOTRANSPLANTATION1,2 by Kroshus, Timothy J., Bolman, R. Morton, Dalmasso, Agustin P.

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EXPRESSION OF HUMAN CD59 IN TRANSGENIC PIG ORGANS ENHANCES ORGAN SURVIVAL IN AN EX VIVO XENOGENEIC PERFUSION MODEL1,2 by Kroshus, Timothy J., Bolman, R. Morton, Dalmasso, Agustin P., Rollins, Scott A., Guilmette, Edward R., Williams, Barry L., Squinto, Stephen P., Fodor, William L.

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Antibody Removal by Column Immunoabsorption Prevents Tissue Injury in an Ex Vivo Model of Pig-to-Human Xenograft Hyperacute Rejection by Kroshus, Timothy J., Dalmasso, Agustin P., Leventhal, Joseph R., John, Ranjit, Matas, Arthur J., Bolman, R.Morton

“…Hyperacute rejection of a pig-to-primate organ xenograft is triggered by binding of anti-pig endothelial cell antibodies to the vascular endothelium of the…”
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Heart transplantation for patients over age 60 by Everett, J E, Djalilian, A R, Kubo, S H, Kroshus, T J, Shumway, S J

“…As the proportion of people over age 60 in our society continues to rise, so does the number of potential heart transplant candidates. Advanced recipient age,…”
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Potential of anticomplement therapy in clinical transplantation by Kroshus, T J, Bolman, 3rd, R M, Dalmasso, A P

“…The activation of complement contributes to tissue damage in many ways. Prevention of complement activation in organ transplantation has largely centred on…”
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