Search Results - "KROPP, Kai A"
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The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
Published in Immunity (Cambridge, Mass.) (24-01-2013)“…Recent studies suggest that the sterol metabolic network participates in the interferon (IFN) antiviral response. However, the molecular mechanisms linking IFN…”
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2
Viral modulation of type II interferon increases T cell adhesion and virus spread
Published in Nature communications (22-06-2024)“…During primary varicella zoster virus (VZV) infection, infected lymphocytes drive primary viremia, causing systemic dissemination throughout the host,…”
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3
Viral enhancer mimicry of host innate-immune promoters
Published in PLoS pathogens (01-02-2014)“…The inflammatory milieu is the natural habitat for a pathogenic infection, characterised by activity of pro-inflammatory signalling pathways and inflammatory…”
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4
Identification of the Cleavage Domain within Glycoprotein G of Herpes Simplex Virus Type 2
Published in Viruses (12-12-2020)“…Glycoprotein G (gG) from herpes simplex virus type 1 and 2 (HSV-1 and HSV-2, respectively) functions as a viral chemokine binding protein (vCKBP). Soluble…”
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5
Cronobacter sakazakii: stress survival and virulence potential in an opportunistic foodborne pathogen
Published in Gut microbes (01-01-2014)“…A characteristic feature of the opportunistic foodborne pathogen Cronobacter sakazakii is its ability to survive in extremely arid environments, such as…”
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6
Viral latency drives ‘memory inflation’: a unifying hypothesis linking two hallmarks of cytomegalovirus infection
Published in Medical microbiology and immunology (01-11-2012)“…Low public awareness of cytomegalovirus (CMV) results from the only mild and transient symptoms that it causes in the healthy immunocompetent host, so that…”
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Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishment of an Immediate-Early Antiviral State
Published in Journal of Virology (01-10-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection
Published in PLoS pathogens (01-04-2015)“…Viral engagement with macrophages activates Toll-Like-Receptors (TLRs) and viruses must contend with the ensuing inflammatory responses to successfully…”
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Journal Article -
9
Colonization of peripheral ganglia by herpes simplex virus type 1 and 2
Published in Current opinion in virology (01-06-2023)“…Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) infect and establish latency in neurons of the peripheral nervous system to persist lifelong in the host and…”
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10
Enhancerless Cytomegalovirus Is Capable of Establishing a Low-Level Maintenance Infection in Severely Immunodeficient Host Tissues but Fails in Exponential Growth
Published in Journal of Virology (01-06-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
Herpes Simplex Virus 2 Counteracts Neurite Outgrowth Repulsion during Infection in a Nerve Growth Factor-Dependent Manner
Published in Journal of virology (29-09-2020)“…During primary infection, herpes simplex virus 2 (HSV-2) replicates in epithelial cells and enters neurites to infect neurons of the peripheral nervous system…”
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12
Innate immune response to SARS‐CoV‐2 infection contributes to neuronal damage in human iPSC‐derived peripheral neurons
Published in Journal of medical virology (01-02-2024)“…Severe acute respiratory coronavirus 2 (SARS‐CoV‐2) causes neurological disease in the peripheral and central nervous system (PNS and CNS, respectively) of…”
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13
Combination of long- and short-read sequencing fully resolves complex repeats of herpes simplex virus 2 strain MS complete genome
Published in Microbial genomics (01-06-2021)“…Herpes simplex virus serotype 2 (HSV-2) is a ubiquitous human pathogen that causes recurrent genital infections and ulcerations. Many HSV-2 strains with…”
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14
Chemokine binding proteins: An immunomodulatory strategy going viral
Published in Cytokine & growth factor reviews (01-08-2016)“…Highlights • Chemokines direct the migration of leukocytes to the site of infection playing a relevant role in the antiviral response. • Some pox- and…”
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15
Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2
Published in Stem cell research (01-10-2021)“…Somatosensory low threshold mechanoreceptors (LTMRs) sense innocuous mechanical forces, largely through specialized axon termini termed sensory nerve endings,…”
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16
Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration
Published in PLoS pathogens (01-05-2017)“…Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection…”
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Journal Article -
17
Reverse Genetics Modification of Cytomegalovirus Antigenicity and Immunogenicity by CD8 T-Cell Epitope Deletion and Insertion
Published in Journal of biomedicine & biotechnology (01-01-2011)“…The advent of cloning herpesviral genomes as bacterial artificial chromosomes (BACs) has made herpesviruses accessible to bacterial genetics and has thus…”
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18
Synergism between the components of the bipartite major immediate-early transcriptional enhancer of murine cytomegalovirus does not accelerate virus replication in cell culture and host tissues
Published in Journal of general virology (01-10-2009)“…Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany Correspondence Matthias J. Reddehase…”
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19
Viral Enhancer Mimicry of Host Innate-Immune Promoters: e1003804
Published in PLoS pathogens (01-02-2014)“…[...]we discuss functional features and regulatory hallmarks that may be used to define viral enhancer mimicry of cellular immune enhancers. Responsiveness to…”
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Journal Article -
20
A Temporal Gate for Viral Enhancers to Co-opt Toll-Like-Receptor Transcriptional Activation Pathways upon Acute Infection: e1004737
Published in PLoS pathogens (01-04-2015)“…Viral engagement with macrophages activates Toll-Like-Receptors (TLRs) and viruses must contend with the ensuing inflammatory responses to successfully…”
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Journal Article