Search Results - "KRONAUER, RICHARD E."

Human responses to bright light of different durations by Chang, Anne‐Marie, Santhi, Nayantara, St Hilaire, Melissa, Gronfier, Claude, Bradstreet, Dayna S., Duffy, Jeanne F., Lockley, Steven W., Kronauer, Richard E., Czeisler, Charles A.

“…Key points •  Light is the strongest time cue for entrainment and phase resetting of the circadian clock. •  In humans, exposure to long‐duration light (6.5 h)…”
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Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light by Gooley, Joshua J, Rajaratnam, Shantha M W, Brainard, George C, Kronauer, Richard E, Czeisler, Charles A, Lockley, Steven W

“…In humans, modulation of circadian rhythms by light is thought to be mediated primarily by melanopsin-containing retinal ganglion cells, not rods or cones…”
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Human phase response curve to a 1 h pulse of bright white light by St Hilaire, Melissa A., Gooley, Joshua J., Khalsa, Sat Bir S., Kronauer, Richard E., Czeisler, Charles A., Lockley, Steven W.

“…Key points •  The human circadian pacemaker generates near‐24‐h rhythms that set the timing of many physiological, metabolic and behavioural body rhythms, and…”
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Human phase response curve to a single 6.5 h pulse of short‐wavelength light by Rüger, Melanie, St Hilaire, Melissa A., Brainard, George C., Khalsa, Sat‐Bir S., Kronauer, Richard E., Czeisler, Charles A., Lockley, Steven W.

“…Key points •  The human ∼24 h circadian pacemaker ensures appropriate timing of physiological, behavioural and metabolic events and is synchronized to the 24 h…”
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Uncovering residual effects of chronic sleep loss on human performance by Cohen, Daniel A, Wang, Wei, Wyatt, James K, Kronauer, Richard E, Dijk, Derk-Jan, Czeisler, Charles A, Klerman, Elizabeth B

“…Sleep loss leads to profound performance decrements. Yet many individuals believe they adapt to chronic sleep loss or that recovery requires only a single…”
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Entrainment of the human circadian pacemaker to longer-than-24-h days by Gronfier, Claude, Wright, Kenneth P. Jr, Kronauer, Richard E, Czeisler, Charles A

“…Entrainment of the circadian pacemaker to the light:dark cycle is necessary for rhythmic physiological functions to be appropriately timed over the 24-h day…”
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Plasticity of the intrinsic period of the human circadian timing system by Scheer, Frank A J L, Wright, Jr, Kenneth P, Kronauer, Richard E, Czeisler, Charles A

“…Human expeditions to Mars will require adaptation to the 24.65-h Martian solar day-night cycle (sol), which is outside the range of entrainment of the human…”
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Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression by Zeitzer, J. M., Dijk, D. J., Kronauer, R., Brown, E., Czeisler, C.

“…Ocular exposure to early morning room light can significantly advance the timing of the human circadian pacemaker. The resetting response to such light has a…”
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Circadian phase resetting by a single short-duration light exposure by Rahman, Shadab A, St Hilaire, Melissa A, Chang, Anne-Marie, Santhi, Nayantara, Duffy, Jeanne F, Kronauer, Richard E, Czeisler, Charles A, Lockley, Steven W, Klerman, Elizabeth B

“…In humans, a single light exposure of 12 minutes and multiple-millisecond light exposures can shift the phase of the circadian pacemaker. We investigated the…”
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Efficacy of a single sequence of intermittent bright light pulses for delaying circadian phase in humans by Gronfier, Claude, Wright, Jr, Kenneth P, Kronauer, Richard E, Jewett, Megan E, Czeisler, Charles A

“…It has been shown in animal studies that exposure to brief pulses of bright light can phase shift the circadian pacemaker and that the resetting action of…”
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Stability, Precision, and Near-24-Hour Period of the Human Circadian Pacemaker by Czeisler, Charles A., Duffy, Jeanne F., Shanahan, Theresa L., Brown, Emery N., Mitchell, Jude F., Rimmer, David W., Ronda, Joseph M., Silva, Edward J., Allan, James S., Emens, Jonathan S., Dijk, Derk-Jan, Kronauer, Richard E.

“…Regulation of circadian period in humans was thought to differ from that of other species, with the period of the activity rhythm reported to range from 13 to…”
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Comparisons of the Variability of Three Markers of the Human Circadian Pacemaker by Klerman, Elizabeth B., Gershengorn, Hayley B., Duffy, Jeanne F., Kronauer, Richard E.

“…A circadian pacemaker within the central nervous system regulates the approximately 24-h physiologic rhythms in sleep cycles, hormone secretion, and other…”
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Intrinsic Near-24-h Pacemaker Period Determines Limits of Circadian Entrainment to a Weak Synchronizer in Humans by Wright, Kenneth P., Hughes, Rod J, Kronauer, Richard E., Dijk, Derk-Jan, Czeisler, Charles A.

“…Endogenous circadian clocks are robust regulators of physiology and behavior. Synchronization or entrainment of biological clocks to environmental time is…”
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Analysis method and experimental conditions affect computed circadian phase from melatonin data by Klerman, Hadassa, St Hilaire, Melissa A, Kronauer, Richard E, Gooley, Joshua J, Gronfier, Claude, Hull, Joseph T, Lockley, Steven W, Santhi, Nayantara, Wang, Wei, Klerman, Elizabeth B

“…Accurate determination of circadian phase is necessary for research and clinical purposes because of the influence of the master circadian pacemaker on…”
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Interactive Mathematical Models of Subjective Alertness and Cognitive Throughput in Humans by Jewett, Megan E., Kronauer, Richard E.

“…The authors present here mathematical models in which levels of subjective alertness and cognitive throughput are predicted by three components that interact…”
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Dose-response relationships for resetting of human circadian clock by light by Boivin, D. B., Duffy, J. F., Kronauer, R. E., Czeisler, C. A.

“…Since the first report in unicells, studies across diverse species have demonstrated that light is a powerful synchronizer which resets, in an…”
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Dynamic resetting of the human circadian pacemaker by intermittent bright light by Rimmer, D W, Boivin, D B, Shanahan, T L, Kronauer, R E, Duffy, J F, Czeisler, C A

“…In humans, experimental studies of circadian resetting typically have been limited to lengthy episodes of exposure to continuous bright light. To evaluate the…”
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Nonphotic entrainment of the human circadian pacemaker by Klerman, E. B., Rimmer, D. W., Dijk, D. J., Kronauer, R. E., Rizzo, J. F. 3rd, Czeisler, C. A.

“…In organisms as diverse as single-celled algae and humans, light is the primary stimulus mediating entrainment of the circadian biological clock. Reports that…”
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A Simpler Model of the Human Circadian Pacemaker by Forger, Daniel B., Jewett, Megan E., Kronauer, Richard E.

“…Numerous studies have used the classic van der Pol oscillator, which contains a cubic nonlinearity, to model the effect of light on the human circadian…”
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An Exploration of the Temporal Dynamics of Circadian Resetting Responses to Short- and Long-Duration Light Exposures: Cross-Species Consistencies and Differences by Kronauer, Richard E., St. Hilaire, Melissa A., Rahman, Shadab A., Czeisler, Charles A., Klerman, Elizabeth B.

“…Light is the most effective environmental stimulus for shifting the mammalian circadian pacemaker. Numerous studies have been conducted across multiple species…”
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