Search Results - "KRITSKI, Afranio"

Strengthening Multidrug-Resistant Tuberculosis Epidemiological Surveillance in Rio de Janeiro: a multidimensional analysis by Bhering, Marcela, Kritski, Afrânio

“…This study aimed to reinforce the importance of the epidemiological surveillance of multidrug-resistant tuberculosis (MDR-TB) in Rio de Janeiro State (RJ)…”
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Predictive factors for unfavourable treatment in MDR-TB and XDR-TB patients in Rio de Janeiro State, Brazil, 2000-2016 by Bhering, Marcela, Duarte, Raquel, Kritski, Afrânio

“…The State of Rio de Janeiro stands out as having the second highest incidence and the highest mortality rate due to TB in Brazil. This study aims at…”
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Primary and acquired multidrug-resistant tuberculosis: Predictive factors for unfavorable treatment outcomes in Rio de Janeiro, 2000-2016 by Bhering, Marcela, Kritski, Afrânio

“…To identify clinical and demographic factors associated with unfavorable treatment outcomes in patients with primary and acquired multidrug-resistant…”
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Trends in primary multidrug-resistant tuberculosis in the State of Rio de Janeiro: a retrospective study conducted during 2000-2019 by Bhering, Marcela, Kritski, Afrânio

“…We analyzed the trends in primary multidrug-resistant tuberculosis (MDR-TB). We performed a time series analysis of primary MDR-TB cases reported in the State…”
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Cost-effectiveness of newer technologies for the diagnosis of Mycobacterium tuberculosis infection in Brazilian people living with HIV by Steffen, Ricardo E., Pinto, Marcia, Kritski, Afranio, Trajman, Anete

“…Tuberculosis is the leading cause of death among people living with HIV (PLH). Preventive tuberculosis therapy reduces mortality in PLH, especially in those…”
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Barriers faced by patients in the diagnosis of multidrug-resistant tuberculosis in Brazil by Bhering, Marcela, Dalcolmo, Margareth, Sarubbi Júnior, Vicente, Kritski, Afrânio

“…OBJECTIVE To understand patients’ narratives about the barriers they faced in the diagnosis and treatment of multidrug-resistant tuberculosis, and their…”
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Unfavorable Outcomes in Tuberculosis: Multidimensional Factors among Adolescents in Rio de Janeiro, Brazil by de Oliveira, Marcia C B, Sant'Anna, Clemax C, Raggio Luiz, Ronir, Kritski, Afrânio L

“…Since 2018, adolescents have been included as a target group for tuberculosis (TB) surveillance by the WHO. However, they are considered a neglected…”
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Tuberculosis Treatment Outcomes in Brazil: Different Predictors for Each Type of Unsuccessful Outcome by Ridolfi, Felipe, Peetluk, Lauren, Amorim, Gustavo, Turner, Megan, Figueiredo, Marina, Cordeiro-Santos, Marcelo, Cavalcante, Solange, Kritski, Afrânio, Durovni, Betina, Andrade, Bruno, Sterling, Timothy R, Rolla, Valeria

“…Abstract Background Successful tuberculosis (TB) treatment is necessary for disease control. The World Health Organization (WHO) has a target TB treatment…”
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Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial by Conde, Marcus B, MD, Efron, Anne, MSN, Loredo, Carla, RN, De Souza, Gilvan R Muzy, MD, Graça, Nadja P, MD, Cezar, Michelle C, MD, Ram, Malathi, PhD, Chaudhary, Mohammad A, PhD, Bishai, William R, Prof, Kritski, Afranio L, MD, Chaisson, Richard E, Prof

“…Summary Background New treatments are needed to shorten the time required to cure tuberculosis and to treat drug-resistant strains. The fluoroquinolone…”
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The Effect of Diabetes and Prediabetes on Antituberculosis Treatment Outcomes: A Multicenter Prospective Cohort Study by Arriaga, María B, Araújo-Pereira, Mariana, Barreto-Duarte, Beatriz, Nogueira, Betânia, Freire, Maria Vitória C N S, Queiroz, Artur T L, Rodrigues, Moreno M S, Rocha, Michael S, Souza, Alexandra B, Spener-Gomes, Renata, Carvalho, Anna Cristina C, Figueiredo, Marina C, Turner, Megan M, Durovni, Betina, Lapa-e-Silva, José R, Kritski, Afrânio L, Cavalcante, Solange, Rolla, Valeria C, Cordeiro-Santos, Marcelo, Sterling, Timothy R, Andrade, Bruno B

“…Abstract Background It is unclear whether diabetes or prediabetes affects unfavorable treatment outcomes and death in people with tuberculosis (PWTB). Methods…”
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Novel stepwise approach to assess representativeness of a large multicenter observational cohort of tuberculosis patients: The example of RePORT Brazil by Arriaga, María B., Amorim, Gustavo, Queiroz, Artur T.L., Rodrigues, Moreno M.S., Araújo-Pereira, Mariana, Nogueira, Betania M.F., Souza, Alexandra Brito, Rocha, Michael S., Benjamin, Aline, Moreira, Adriana S.R., de Oliveira, Jamile G., Figueiredo, Marina C., Turner, Megan M., Alves, Kleydson, Durovni, Betina, Lapa-e-Silva, José R., Kritski, Afrânio L., Cavalcante, Solange, Rolla, Valeria C., Cordeiro-Santos, Marcelo, Sterling, Timothy R., Andrade, Bruno B.

“…•The representativeness of a large TB cohort was tested using the Brazilian National TB databank.•The novel analysis of second-generation p-values uncovered…”
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Learning from the Italian experience in coping with COVID-19 by Carvalho, Anna Cristina Calçada, Kritski, Afrânio

“…In March 2020, the rapid increase in COVID-19 cases overburdened the Italian health system, with the country becoming the pandemic's epicenter. We present a…”
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Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil by Verza, Mirela, Scheffer, Mara Cristina, Salvato, Richard Steiner, Schorner, Marcos André, Barazzetti, Fernando Hartmann, Machado, Hanalydia de Melo, Medeiros, Taiane Freitas, Rovaris, Darcita Buerger, Portugal, Isabel, Viveiros, Miguel, Perdigão, João, Kritski, Afrânio, Bazzo, Maria Luiza

“…Mycobacterium tuberculosis ( M.tb ), the pathogen responsible for tuberculosis (TB) poses as the major cause of death among infectious diseases. The knowledge…”
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Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice by Almeida, Fabrício M, Ventura, Thatiana L B, Amaral, Eduardo P, Ribeiro, Simone C M, Calixto, Sanderson D, Manhães, Marcelle R, Rezende, Andreza L, Souza, Giliane S, de Carvalho, Igor S, Silva, Elisangela C, Silva, Juliana Azevedo da, Carvalho, Eulógio C Q, Kritski, Afranio L, Lasunskaia, Elena B

“…Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) that in most cases induces irreversible necrosis of lung tissue as…”
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Treatment outcomes of MDR-tuberculosis patients in Brazil: a retrospective cohort analysis by Bastos, Mayara Lisboa, Cosme, Lorrayne Beliqui, Fregona, Geisa, do Prado, Thiago Nascimento, Bertolde, Adelmo Inácio, Zandonade, Eliana, Sanchez, Mauro N, Dalcolmo, Margareth Pretti, Kritski, Afrânio, Trajman, Anete, Maciel, Ethel Leonor Noia

“…Multidrug-resistant tuberculosis (MDR-TB) is a threat for the global TB epidemic control. Despite existing evidence that individualized treatment of MDR-TB is…”
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Sustained elevated levels of C-reactive protein and ferritin in pulmonary tuberculosis patients remaining culture positive upon treatment initiation by Miranda, Pryscila, Gil-Santana, Leonardo, Oliveira, Marina G, Mesquita, Eliene D D, Silva, Elisangela, Rauwerdink, Anneloek, Cobelens, Frank, Oliveira, Martha M, Andrade, Bruno B, Kritski, Afrânio

“…Clinical trials that evaluate new anti-tubercular drugs and treatment regimens take years to complete due to the slow clearance of Mycobacterium tuberculosis…”
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Isoniazid Monoresistance and Antituberculosis Treatment Outcome in Persons With Pulmonary Tuberculosis in Brazil by Araújo-Pereira, Mariana, Arriaga, María B, Carvalho, Anna Cristina C, Spener-Gomes, Renata, Schmaltz, Carolina A S, Nogueira, Betânia M F, Figueiredo, Marina C, Turner, Megan M, Cordeiro-Santos, Marcelo, Rolla, Valeria C, Sterling, Timothy R, Andrade, Bruno B, Kritski, Afrânio L

“…The high burden of drug-resistant tuberculosis (TB) is a problem to achieve the goals of the End TB Strategy by 2035. Whether isoniazid monoresistance (Hr)…”
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Effect of Smoking on Longitudinal Interferon γ Release Assay Results Among Close Contacts of People with Pulmonary Tuberculosis by Arriaga, María B, Amorim, Gustavo, Figueiredo, Marina C, Staats, Cody, Kritski, Afrânio L, Cordeiro-Santos, Marcelo, Rolla, Valeria C, Andrade, Bruno B, Sterling, Timothy R, Andrade, Alice M S, Rocha, Michael S, Nascimento, Vanessa, Cubillos-Angulo, Juan M, Rebouças-Silva, Jéssica, Viana, Sayonara M, Brito, Pedro, Santos, Saulo R N, Ramos, André, Costa, Alysson G, Silva, Jaquelane, de Oliveira, Jamile G, Benjamin, Aline, Gomes-Silva, Adriano, Sant'Anna, Flavia M, Ignácio, Francine P, Lourenço, Maria Cristina, Silva, Elisangela C, Moreira, Adriana S R, Mello, Mayla, Turner, Megan

“…Diagnosis of Mycobacterium tuberculosis infection in close contacts is critical for tuberculosis control. Smoking is a risk factor for M. tuberculosis…”
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Tuberculosis-associated anemia is linked to a distinct inflammatory profile that persists after initiation of antitubercular therapy by Gil-Santana, Leonardo, Cruz, Luís A. B., Arriaga, María B., Miranda, Pryscila F. C., Fukutani, Kiyoshi F., Silveira-Mattos, Paulo S., Silva, Elisangela C., Oliveira, Marina G., Mesquita, Eliene D. D., Rauwerdink, Anneloek, Cobelens, Frank, Oliveira, Martha M., Kritski, Afranio, Andrade, Bruno B.

“…Pulmonary tuberculosis (PTB) is associated with chronic inflammation and anemia. How anemia impacts systemic inflammation in PTB patients undergoing…”
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Associations between systemic inflammation, mycobacterial loads in sputum and radiological improvement after treatment initiation in pulmonary TB patients from Brazil: a prospective cohort study by Mesquita, Eliene D D, Gil-Santana, Leonardo, Ramalho, Daniela, Tonomura, Elise, Silva, Elisangela C, Oliveira, Martha M, Andrade, Bruno B, Kritski, Afrânio

“…Mycobacterium tuberculosis infection is known to cause inflammation and lung tissue damage in high-risk populations. Nevertheless, direct associations between…”
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