Search Results - "KRISTIANSSON, ERIK"
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Environmental factors influencing the development and spread of antibiotic resistance
Published in FEMS microbiology reviews (01-01-2018)“…Abstract Antibiotic resistance and its wider implications present us with a growing healthcare crisis. Recent research points to the environment as an…”
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Comparison of normalization methods for the analysis of metagenomic gene abundance data
Published in BMC genomics (20-04-2018)“…In shotgun metagenomics, microbial communities are studied through direct sequencing of DNA without any prior cultivation. By comparing gene abundances…”
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3
Economic interests cloud hazard reductions in the European regulation of substances of very high concern
Published in Nature communications (05-11-2022)“…Here we investigate how the conflicts between hazard reduction and economic interests have shaped the regulation of substances of very high concern (SVHCs)…”
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4
The structure and diversity of human, animal and environmental resistomes
Published in Microbiome (07-10-2016)“…Antibiotic resistance genes (ARGs) are widespread but cause problems only when present in pathogens. Environments where selection and transmission of…”
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Pharmacology beyond the patient – The environmental risks of human drugs
Published in Environment international (01-08-2019)“…The presence of pharmaceuticals in the environment is a growing global concern and although environmental risk assessment is required for approval of new drugs…”
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Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics
Published in The Science of the total environment (01-12-2016)“…Sewage treatment plants (STPs) have repeatedly been suggested as “hotspots” for the emergence and dissemination of antibiotic-resistant bacteria. A critical…”
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Pyrosequencing of antibiotic-contaminated river sediments reveals high levels of resistance and gene transfer elements
Published in PloS one (16-02-2011)“…The high and sometimes inappropriate use of antibiotics has accelerated the development of antibiotic resistance, creating a major challenge for the…”
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Evolutionary Conservation of Human Drug Targets in Organisms used for Environmental Risk Assessments
Published in Environmental science & technology (01-08-2008)“…Pharmaceuticals are typically found in very low concentrations in the aquatic environment. Accordingly, environmental effects clearly assigned to residual…”
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9
Selective concentration for ciprofloxacin resistance in Escherichia coli grown in complex aquatic bacterial biofilms
Published in Environment international (01-07-2018)“…There is concern that antibiotics in the environment can select for and enrich bacteria carrying acquired antibiotic resistance genes, thus increasing the…”
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10
Introducing ribosomal tandem repeat barcoding for fungi
Published in Molecular ecology resources (01-01-2019)“…Sequence comparison and analysis of the various ribosomal genetic markers are the dominant molecular methods for identification and description of fungi…”
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Improved software detection and extraction of ITS1 and ITS2 from ribosomal ITS sequences of fungi and other eukaryotes for analysis of environmental sequencing data
Published in Methods in ecology and evolution (01-10-2013)“…Summary The nuclear ribosomal internal transcribed spacer (ITS) region is the primary choice for molecular identification of fungi. Its two highly variable…”
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Long-term application of Swedish sewage sludge on farmland does not cause clear changes in the soil bacterial resistome
Published in Environment international (01-04-2020)“…•Application of sewage sludge did not cause accumulation of antibiotics in soil.•There was no detected increase in phenotypic resistance after sludge…”
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The impact of the ST131 clone on recurrent ESBL-producing E. coli urinary tract infection: a prospective comparative study
Published in Scientific reports (16-06-2022)“…The global emergence of extended-spectrum beta-lactamase-producing Escherichia coli (ESBL- E. coli ), mainly causing urinary tract infections (UTI), is of…”
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14
Taxonomic reliability of DNA sequences in public sequence databases: a fungal perspective
Published in PloS one (20-12-2006)“…DNA sequences are increasingly seen as one of the primary information sources for species identification in many organism groups. Such approaches, popularly…”
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15
A framework for identifying the recent origins of mobile antibiotic resistance genes
Published in Communications biology (04-01-2021)“…Since the introduction of antibiotics as therapeutic agents, many bacterial pathogens have developed resistance to antibiotics. Mobile resistance genes,…”
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Discovery of the fourth mobile sulfonamide resistance gene
Published in Microbiome (15-12-2017)“…Over the past 75 years, human pathogens have acquired antibiotic resistance genes (ARGs), often from environmental bacteria. Integrons play a major role in the…”
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17
Shotgun metagenomics reveals a wide array of antibiotic resistance genes and mobile elements in a polluted lake in India
Published in Frontiers in microbiology (2014)“…There is increasing evidence for an environmental origin of many antibiotic resistance genes. Consequently, it is important to identify environments of…”
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18
Phosphorylated CtIP bridges DNA to promote annealing of broken ends
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-2020)“…The early steps of DNA double-strand break (DSB) repair in human cells involve the MRE11-RAD50-NBS1 (MRN) complex and its cofactor, phosphorylated CtIP. The…”
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HirBin: high-resolution identification of differentially abundant functions in metagenomes
Published in BMC genomics (21-04-2017)“…Gene-centric analysis of metagenomics data provides information about the biochemical functions present in a microbiome under a certain condition. The ability…”
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Evidence for wastewaters as environments where mobile antibiotic resistance genes emerge
Published in Communications biology (25-03-2023)“…The emergence and spread of mobile antibiotic resistance genes (ARGs) in pathogens have become a serious threat to global health. Still little is known about…”
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