Search Results - "KRISHNAN, Jaya"

Cavefish and the basis for eye loss by Krishnan, Jaya, Rohner, Nicolas

“…Animals have colonized the entire world from rather moderate to the harshest environments, some of these so extreme that only few animals are able to survive…”
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Non-coding RNAs in Cardiac Regeneration by Yuan, Ting, Krishnan, Jaya

“…The adult heart has a limited capacity to replace or regenerate damaged cardiac tissue following severe myocardial injury. Thus, therapies facilitating the…”
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Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction by Trembinski, D. Julia, Bink, Diewertje I., Theodorou, Kosta, Sommer, Janina, Fischer, Ariane, van Bergen, Anke, Kuo, Chao-Chung, Costa, Ivan G., Schürmann, Christoph, Leisegang, Matthias S., Brandes, Ralf P., Alekseeva, Tijna, Brill, Boris, Wietelmann, Astrid, Johnson, Christopher N., Spring-Connell, Alexander, Kaulich, Manuel, Werfel, Stanislas, Engelhardt, Stefan, Hirt, Marc N., Yorgan, Kaja, Eschenhagen, Thomas, Kirchhof, Luisa, Hofmann, Patrick, Jaé, Nicolas, Wittig, Ilka, Hamdani, Nazha, Bischof, Corinne, Krishnan, Jaya, Houtkooper, Riekelt H., Dimmeler, Stefanie, Boon, Reinier A.

“…Long non-coding RNAs (lncRNAs) contribute to cardiac (patho)physiology. Aging is the major risk factor for cardiovascular disease with cardiomyocyte apoptosis…”
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SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes by Bojkova, Denisa, Wagner, Julian U G, Shumliakivska, Mariana, Aslan, Galip S, Saleem, Umber, Hansen, Arne, Luxán, Guillermo, Günther, Stefan, Pham, Minh Duc, Krishnan, Jaya, Harter, Patrick N, Ermel, Utz H, Frangakis, Achilleas S, Milting, Hendrik, Zeiher, Andreas M, Klingel, Karin, Cinatl, Jindrich, Dendorfer, Andreas, Eschenhagen, Thomas, Tschöpe, Carsten, Ciesek, Sandra, Dimmeler, Stefanie

“…Abstract Aims Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has emerged as a global pandemic…”
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Poor eyesight reveals a new vision gene by Biswas, Tathagata, Krishnan, Jaya, Rohner, Nicolas

“…Comparing the genomes of mammals which evolved to have poor vision identifies an important gene for eyesight…”
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Seismic Performance of Cementitious Grout Filled Coupler and Sleeve Connections in Precast Wall Panels under Cyclic Lateral Loading by PARISUTHAM, Joyson Silva, KRISHNAN PRABHAKARAN, Jaya, SUKUMAR, Binu

“…This study investigated the seismic performance of cementitious grout filled coupler and sleeve connections in precast wall panels under cyclic lateral…”
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The metabolome of Mexican cavefish shows a convergent signature highlighting sugar, antioxidant, and Ageing-Related metabolites by Medley, J Kyle, Persons, Jenna, Biswas, Tathagata, Olsen, Luke, Peuß, Robert, Krishnan, Jaya, Xiong, Shaolei, Rohner, Nicolas

“…Insights from organisms, which have evolved natural strategies for promoting survivability under extreme environmental pressures, may help guide future…”
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Emerging trends of long non‐coding RNAs in gene activation by Krishnan, Jaya, Mishra, Rakesh K.

“…The RNA world has gained increasing importance in the recent past as its role beyond coding for proteins and components of translational machinery is becoming…”
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Exploiting the hypoxia sensitive non-coding genome for organ-specific physiologic reprogramming by Bischof, Corinne, Krishnan, Jaya

“…In this review we highlight the role of non-coding RNAs in the development and progression of cardiac pathology and explore the possibility of…”
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Cardiac Raptor Ablation Impairs Adaptive Hypertrophy, Alters Metabolic Gene Expression, and Causes Heart Failure in Mice by SHENDE, Pankaj, PLAISANCE, Isabelle, PEDRAZZINI, Thierry, BRINK, Marijke, MORANDI, Christian, PELLIEUX, Corinne, BERTHONNECHE, Corinne, ZORZATO, Francesco, KRISHNAN, Jaya, LERCH, Rene, HALL, Michael N, RÜEGG, Markus A

“…Cardiac hypertrophy involves growth responses to a variety of stimuli triggered by increased workload. It is an independent risk factor for heart failure and…”
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Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation by Krishnan, Jaya, Wang, Yan, Kenzior, Olga, Hassan, Huzaifa, Olsen, Luke, Tsuchiya, Dai, Kenzior, Alexander, Peuß, Robert, Xiong, Shaolei, Wang, Yongfu, Zhao, Chongbei, Rohner, Nicolas

“…Cell lines have become an integral resource and tool for conducting biological experiments ever since the Hela cell line was first developed (Scherer et al. in…”
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The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury in murine males by Rogala, Sandra, Ali, Tamer, Melissari, Maria-Theodora, Währisch, Sandra, Schuster, Peggy, Sarre, Alexandre, Emídio, Rebeca Cordellini, Boettger, Thomas, Rogg, Eva-Maria, Kaur, Jaskiran, Krishnan, Jaya, Dumbović, Gabrijela, Dimmeler, Stefanie, Ounzain, Samir, Pedrazzini, Thierry, Herrmann, Bernhard G., Grote, Phillip

“…After myocardial infarction in the adult heart the remaining, non-infarcted tissue adapts to compensate the loss of functional tissue. This adaptation requires…”
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Avian cultural services peak in tropical wet forests by Echeverri, Alejandra, Karp, Daniel S., Frishkoff, Luke O., Krishnan, Jaya, Naidoo, Robin, Zhao, Jiaying, Zook, Jim, Chan, Kai M. A.

“…The current biodiversity crisis involves major shifts in biological communities at local and regional scales. The consequences for Earth's life‐support systems…”
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Adaptation to low parasite abundance affects immune investment and immunopathological responses of cavefish by Peuß, Robert, Box, Andrew C., Chen, Shiyuan, Wang, Yongfu, Tsuchiya, Dai, Persons, Jenna L., Kenzior, Alexander, Maldonado, Ernesto, Krishnan, Jaya, Scharsack, Jörn P., Slaughter, Brian D., Rohner, Nicolas

“…Reduced parasitic infection rates in the developed world are suspected to underlie the rising prevalence of autoimmune disorders. However, the long-term…”
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CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes by Zhu, Chaonan, Baumgarten, Nina, Wu, Meiqian, Wang, Yue, Das, Arka Provo, Kaur, Jaskiran, Ardakani, Fatemeh Behjati, Duong, Thanh Thuy, Pham, Minh Duc, Duda, Maria, Dimmeler, Stefanie, Yuan, Ting, Schulz, Marcel H, Krishnan, Jaya

“…Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Genome-wide association studies (GWAS) have identified many single nucleotide…”
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Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus by Patrick, David M, de la Visitación, Néstor, Krishnan, Jaya, Chen, Wei, Ormseth, Michelle J, Stein, C Michael, Davies, Sean S, Amarnath, Venkataraman, Crofford, Leslie J, Williams, Jonathan M, Zhao, Shilin, Smart, Charles D, Dikalov, Sergey, Dikalova, Anna, Xiao, Liang, Van Beusecum, Justin P, Ao, Mingfang, Fogo, Agnes B, Kirabo, Annet, Harrison, David G

“…We describe a mechanism responsible for systemic lupus erythematosus (SLE). In humans with SLE and in 2 SLE murine models, there was marked enrichment of…”
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Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus by Patrick, David M., de la Visitación, Néstor, Krishnan, Jaya, Chen, Wei, Ormseth, Michelle J., Stein, C. Michael, Davies, Sean S., Amarnath, Venkataraman, Crofford, Leslie J., Williams, Jonathan M., Zhao, Shilin, Smart, Charles D., Dikalov, Sergey, Dikalova, Anna, Xiao, Liang, Van Beusecum, Justin P., Ao, Mingfang, Fogo, Agnes B., Kirabo, Annet, Harrison, David G.

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Markers for the lymphatic endothelium: In search of the holy grail? by Sleeman, Jonathan P., Krishnan, Jaya, Kirkin, Vladimir, Baumann, Petra

“…The ability to discriminate reliably at the histological level between blood and lymphatic microcapillaries would greatly assist the study of a number of…”
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GATA simple sequence repeats function as enhancer blocker boundaries by Kumar, Ram P., Krishnan, Jaya, Pratap Singh, Narendra, Singh, Lalji, Mishra, Rakesh K.

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Sweet fish: Fish models for the study of hyperglycemia and diabetes by Krishnan, Jaya, Rohner, Nicolas

“…Fish are good for your health in more ways than you may expect. For one, eating fish is a common dietary recommendation for a healthy diet. However, fish have…”
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