Search Results - "KRISHNAN, Aruna V"

The role of vitamin D in reducing cancer risk and progression by Feldman, David, Krishnan, Aruna V., Swami, Srilatha, Giovannucci, Edward, Feldman, Brian J.

“…Key Points Vitamin D 3 is the precursor to the potent steroid hormone calcitriol (1,25 dihydroxyvitamin D 3 (1,25(OH) 2 D 3 )) that regulates the expression of…”
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Mechanisms of the Anti-Cancer and Anti-Inflammatory Actions of Vitamin D by KRISHNAN, Aruna V, FELDMAN, David

“…Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an anti-cancer agent. Calcitriol exerts multiple…”
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Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments: A Scientific Statement From the American Heart Association by Volgman, Annabelle Santos, Palaniappan, Latha S, Aggarwal, Neelum T, Gupta, Milan, Khandelwal, Abha, Krishnan, Aruna V, Lichtman, Judith H, Mehta, Laxmi S, Patel, Hena N, Shah, Kevin S, Shah, Svati H, Watson, Karol E

“…South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka) make up one quarter of the world’s population and are one of the…”
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Molecular pathways mediating the anti-inflammatory effects of calcitriol: implications for prostate cancer chemoprevention and treatment by Krishnan, Aruna V, Feldman, David

“…Calcitriol, the hormonally active form of vitamin D, exerts multiple anti-proliferative and pro-differentiating actions including cell cycle arrest and…”
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The potential therapeutic benefits of vitamin D in the treatment of estrogen receptor positive breast cancer by Krishnan, Aruna V., Swami, Srilatha, Feldman, David

“…► Calcitriol, (active form of vitamin D) exerts anticancer effects in breast cancer models. ► Calcitriol inhibits prostaglandin synthesis and exerts…”
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Tissue-Selective Regulation of Aromatase Expression by Calcitriol: Implications for Breast Cancer Therapy by Krishnan, Aruna V, Swami, Srilatha, Peng, Lihong, Wang, Jining, Moreno, Jacqueline, Feldman, David

“…Aromatase, the enzyme that catalyzes estrogen synthesis, is critical for the progression of estrogen receptor-positive breast cancer (BCa) in postmenopausal…”
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The Role of Vitamin D in Cancer Prevention and Treatment by Krishnan, Aruna V., PhD, Trump, Donald L., MD, Johnson, Candace S., PhD, Feldman, David, MD

“…Calcitriol (1,25-dihydroxyvitamin D3 ), the hormonally active form of vitamin D, exerts growth inhibitory and prodifferentiating effects on many malignant…”
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Years of Potential Life Lost Because of Cardiovascular Disease in Asian-American Subgroups, 2003-2012 by Iyer, Divya G, Shah, Nilay S, Hastings, Katherine G, Hu, Jiaqi, Rodriguez, Fatima, Boothroyd, Derek B, Krishnan, Aruna V, Falasinnu, Titilola, Palaniappan, Latha

“…Background Asian-American subgroups (Asian-Indian, Chinese, Filipino, Korean, Japanese, and Vietnamese) display varied cardiovascular disease mortality…”
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Transrepression of the estrogen receptor promoter by calcitriol in human breast cancer cells via two negative vitamin D response elements by Swami, Srilatha, Krishnan, Aruna V, Peng, Lihong, Lundqvist, Johan, Feldman, David

“…Calcitriol (1,25-dihydroxyvitamin D3), the hormonally active metabolite of vitamin D, exerts its anti-proliferative activity in breast cancer (BCa) cells by…”
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Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells by MORENO, Jacqueline, KRISHNAN, Aruna V, SWAMI, Srilatha, NONN, Larisa, PEEHL, Donna M, FELDMAN, David

“…Calcitriol exhibits antiproliferative and pro-differentiation effects in prostate cancer. Our goal is to further define the mechanisms underlying these…”
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The Role of Vitamin D in Cancer Prevention and Treatment by Krishnan, Aruna V., PhD, Trump, Donald L., MD, Johnson, Candace S., PhD, Feldman, David, MD

“…Calcitriol (1,25-dihydroxyvitamin D3 ), the hormonally active form of vitamin D, exerts growth inhibitory and prodifferentiating effects on many malignant…”
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Molecular mechanisms mediating the anti-proliferative effects of Vitamin D in prostate cancer by Moreno, Jacqueline, Krishnan, Aruna V., Feldman, David

“…Calcitriol (1,25-dihydroxyvitamin D 3) inhibits the growth and stimulates the differentiation of prostate cancer (PCa) cells. The effects of calcitriol are…”
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Genistein potentiates the growth inhibitory effects of 1,25-dihydroxyvitamin D3 in DU145 human prostate cancer cells: role of the direct inhibition of CYP24 enzyme activity by Swami, Srilatha, Krishnan, Aruna V, Peehl, Donna M, Feldman, David

“…In a search for improved therapies for prostate cancer, we investigated the effect of genistein in combination with 1alpha-25-dihydroxyvitamin D3…”
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Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients by Swami, Srilatha, Krishnan, Aruna V., Moreno, Jacqueline, Bhattacharyya, Rumi S., Gardner, Christopher, Brooks, James D., Peehl, Donna M., Feldman, David

“…Soy and its constituent isoflavone genistein inhibit the development and progression of prostate cancer (PCa). Our study in both cultured cells and PCa…”
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Calcitriol as a Chemopreventive and Therapeutic Agent in Prostate Cancer: Role of Anti‐Inflammatory Activity by Krishnan, Aruna V, Moreno, Jacqueline, Nonn, Larisa, Swami, Srilatha, Peehl, Donna M, Feldman, David

“…Calcitriol, the hormonally active form of vitamin D, inhibits the growth and development of several cancers. Inflammation has been implicated in the…”
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Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells by Bhattacharyya, Rumi S, Krishnan, Aruna V, Swami, Srilatha, Feldman, David

“…The androgen receptor (AR) plays a key role in the development and progression of prostate cancer. Targeting the AR for down-regulation would be a useful…”
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Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays by Krishnan, Aruna V., Shinghal, Rajesh, Raghavachari, Nalini, Brooks, James D., Peehl, Donna M., Feldman, David

“…BACKGROUND 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3] exerts growth inhibitory, pro‐differentiating, and pro‐apoptotic effects on prostate cells. To better…”
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Mechanisms of Vitamin D-mediated Growth Inhibition in Prostate Cancer Cells: Inhibition of the Prostaglandin Pathway by MORENO, Jacqueline, KRISHNAN, Aruna V, PEEHL, Donna M, FELDMAN, David

“…Calcitriol (1,25-dihydroxyvitamin D 3 ), the active form of vitamin D, promotes growth inhibition and differentiation in prostate cancer (PCa) cells. To…”
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Vitamin D and breast cancer: Inhibition of estrogen synthesis and signaling by Krishnan, Aruna V., Swami, Srilatha, Feldman, David

“…Calcitriol (1,25-dihydroxyvitamin D 3), the hormonally active metabolite of vitamin D, inhibits the growth and induces the differentiation of many malignant…”
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Pathways mediating the growth-inhibitory actions of vitamin D in prostate cancer by Peehl, Donna M, Krishnan, Aruna V, Feldman, David

“…Vitamin D is emerging as an important dietary factor that affects the incidence and progression of many malignancies including prostate cancer. The active form…”
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