Search Results - "KRIEGER, Timothy J"

Dosage form development, in vitro release kinetics, and in vitro-in vivo correlation for leuprolide released from an implantable multi-reservoir array by PRESCOTT, James H, KRIEGER, Timothy J, LIPKA, Sara, STAPLES, Mark A

“…Implanted multi-reservoir arrays improve dosing control relative to osmotic pumps or polymer depots. The limited reservoir volume requires concentrated…”
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Purification and Characteristics of the Candidate Prohormone Processing Proteases PC2 and PC1/3 from Bovine Adrenal Medulla Chromaffin Granules (∗) by Azaryan, Anahit V., Krieger, Timothy J., Hook, Vivian Y.H.

“…The prohormone-processing proteases PC1/3 and PC2 belong to the family of mammalian subtilisin-related proprotein convertases (PC) possessing homology to the…”
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Purification and characterization of a novel tripeptidyl aminopeptidase from Streptomyces lividans 66 by Krieger, Timothy J., Bartfeld, Daniel, Jenish, David L., Hadary, Dany

“…An extracellular tripeptidyl aminopeptidase has been purified from Streptomyces lividans 66 cell-free cultures. The enzyme is a major component of the secreted…”
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Prohormone thiol protease and enkephalin precursor processing: cleavage at dibasic and monobasic sites by Krieger, T J, Mende-Mueller, L, Hook, V Y

“…Production of active enkephalin peptides requires proteolytic processing of proenkephalin at dibasic Lys-Arg, Arg-Arg, and Lys-Lys sites, as well as cleavage…”
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Purification and characterization of a cathepsin D protease from bovine chromaffin granules by Krieger, Timothy J, Hook, Vivian Y. H

“…Purification and potential tachykinin and enkephalin precursor cleaving enzymes from bovine chromaffin granules was undertaken using as substrates the model…”
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Affinity labeling and purification of spinach leaf ribulose-5-phosphate kinase by Krieger, Timothy J, Miziorko, Henry M

“…Spinach leaf ribulose-5-phosphate kinase has been purified to homogeneity by a procedure incorporating affinity chromatography. The purified enzyme requires a…”
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Purification and characterization of a novel thiol protease involved in processing the enkephalin precursor by KRIEGER, T. J, HOOK, V. Y. H

“…Proteolytic processing enzymes are required to convert the enkephalin precursor to active opioid peptides. In this study, a novel 33-kDa thiol protease that…”
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Purification and characterization of α1-antichymotrypsin-like protease inhibitor that regulates prohormone thiol protease involved in enkephalin precursor processing by HOOK, V. Y. H, PURVIANCE, R. T, AZARYAN, A. V, HUBBARD, G, KRIEGER, T. J

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Stimulation of Prohormone Thiol Protease (PTP) and MetEnkephalin by Forskolin by Nikolaos Tezapsidis, Stephen Noctor, Rama Kannan, Timothy J. Krieger, Liane Mende-Mueller, Vivian Y. H. Hook

“…Proenkephalin and other prohormones require proteolytic processing at paired basic and monobasic residues for the biosynthesis of active neuropeptides. The…”
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Stimulation of “Prohormone Thiol Protease” (PTP) and [Met]Enkephalin by Forskolin by Tezapsidis, Nikolaos, Noctor, Stephen, Kannan, Rama, Krieger, Timothy J., Mende-Mueller, Liane, Hook, Vivian Y.H.

“…Proenkephalin and other prohormones require proteolytic processing at paired basic and monobasic residues for the biosynthesis of active neuropeptides. The…”
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Affinity labeling of spinach leaf phosphoribulokinase by ATP analogs: modification of an active site lysine by Miziorko, H.M. (Medical College of Wisconsin, Milwaukee, WI), Brodt, C.A, Krieger, T.J

“…Spinach leaf phosphoribulokinase is sensitive to modification by ATP analogs that react with lysine residues. The 2',3'-dialdehyde derivative of ATP (oATP)…”
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Spinach leaf ribulose-5-phosphate kinase: examination of sulfhydryls by chemical modification and spin-labeling by Krieger, T J, Miziorko, H M

“…Methodology has been developed for complete or selective modification of the cysteinyl sulfhydryls of ribulose-5-phosphate (Ru5P) kinase. Using native enzyme,…”
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