Search Results - "KRETSCHMER, Peter J"

Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models by Leong, Lilley, Sim, Derek, Patel, Chandra, Tran, Katherine, Liu, Perry, Ho, Elena, Thompson, Thomas, Kretschmer, Peter J., Wakabayashi, Hironao, Fay, Philip J., Murphy, John E.

“…An important negative regulator of factor VIIIa (FVIIIa) cofactor activity is A2 subunit dissociation. FVIII molecules with stabilized activity have been…”
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Identification of a novel prostate tumor target, Mindin/RG-1, for antibody-based radiotherapy of prostate cancer by PARRY, Renate, SCHNEIDER, Doug, BIROC, Sandra, KRETSCHMER, Peter J, HALKS-MILLER, Meredith, KLOCKER, Helmut, YING ZHU, LARSEN, Brent, COBB, Ronald R, BRINGMANN, Peter, ROTH, Georg, LEWIS, Jason S, HUDSON, Debra, DINTER, Harald, PARRY, Gordon, PARKES, Debbie, XUAN, Jian-Ai, NEWTON, Alicia, TOY, Pam, LIN, Rick, HARKINS, Rick, ALICKE, Bruno

“…Gene expression analysis showed that a human mindin homologue, mindin/RG-1, is expressed selectively in prostate tissues and that its expression level is…”
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Development and Validation of a Robust and Versatile One-plasmid Regulated Gene Expression System by Szymanski, Paul, Kretschmer, Peter J, Bauzon, Maxine, Jin, Fang, Qian, Hu Sheng, Rubanyi, Gabor M, Harkins, Richard N, Hermiston, Terry W

“…We have developed a one-plasmid regulated gene expression system, pBRES, based on a mifepristone (MFP)-inducible two-plasmid system. The various expression…”
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Catchment-scale groundwater-flow and recharge paradox revealed from base flow analysis during the Australian Millennium Drought (Mt Lofty Ranges, South Australia) by Anderson, Thomas T., Bestland, Erick A., Wallis, Ilka, Kretschmer, Peter J. C., Soloninka, Lesja, Banks, Edward W., Werner, Adrian D., Cendón, Dioni I., Pichler, Markus M., Guan, Huade

“…Catchment-scale recharge and water balance estimates are commonly made for the purposes of water resource management. Few catchments have had these estimates…”
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Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor by Liang, Meina, Rosser, Mary, Ng, Howard P, May, Karen, Bauman, John G, Islam, Imadul, Ghannam, Ameen, Kretschmer, Peter J, Pu, Haifeng, Dunning, Laura, Snider, R.Michael, Morrissey, Michael M, Hesselgesser, Joseph, Perez, H.Daniel, Horuk, Richard

“…The species specificity of a small molecule antagonist for the human CCR1 chemokine receptor, 2-2-diphenyl-5-(4-chlorophenyl)piperidin-1-yl)valeronitrile (CCR1…”
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Enhanced protein production using HBV X protein (HBx), and synergy when used in combination with XBP1s in BHK21 cells by Jin, Fang, Kretschmer, Peter J., Harkins, Richard N., Hermiston, Terry W.

“…The demand of therapeutic protein production from mammalian cells has expanded greatly since the first biologic was approved in 1982. It remains a major…”
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Identification of Novel Insertion Sites in the Ad5 Genome That Utilize the Ad Splicing Machinery for Therapeutic Gene Expression by Jin, Fang, Kretschmer, Peter J, Hermiston, Terry W

“…Therapeutic transgene expression from oncolytic viruses represents one approach to increasing the effectiveness of these agents as cancer therapeutics. In the…”
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Development of a transposon-based approach for identifying novel transgene insertion sites within the replicating adenovirus by Kretschmer, Peter J, Jin, Fang, Chartier, Cecile, Hermiston, Terry W

“…Therapeutic gene delivery from an oncolytic adenovirus (Ad) is one approach to enhancing the potency of Ad-based virotherapies for cancer. To identify…”
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Rapid establishment of high-producing cell lines using dicistronic vectors with glutamine synthetase as the selection marker by HAIFENG PU, CASHION, L. M, KRETSCHMER, P. J, ZHONG LIU

“…Recombinant proteins are useful tools in biological research, drug development, and drug screening. Specially designed expression vectors have been developed…”
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Heparin-binding neurotrophic factor (HBNF) and MK, members of a new family of homologous, developmentally regulated proteins by Kovesdi, I, Fairhurst, J L, Kretschmer, P J, Böhlen, P

“…A partial rat cDNA clone coding for a novel neurotrophic factor HBNF was isolated. Nucleotide sequence determination, in combination with the known N-terminal…”
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Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins by Kretschmer, P J, Fairhurst, J L, Decker, M M, Chan, C P, Gluzman, Y, Böhlen, P, Kovesdi, I

“…This report describes the cloning, expression and characterization of two members of a novel human gene family of proteins, HBNF and MK, which exhibit neurite…”
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Molecular cloning of the K1 capsular polysaccharide genes of E. coli by Silver, Richard P, Finn, Charles W, Vann, Willie F, Aaronson, Wendy, Schneerson, Rachel, Kretschmer, Peter J, Garon, Claude F

“…Epidemiological and immunological evidence indicates that the K1 capsular polysaccharide confers the property of virulence on Escherichia coli. E coli K1 is…”
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Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species by Yuan, Thomas Ta-Tung, Toy, Pamela, McClary, John A., Lin, Richard J., Miyamoto, Neil G., Kretschmer, Peter J.

“…We have cloned the full-length cDNA and genomic region of a human prostate specific G-protein coupled receptor with properties characteristic of an olfactory…”
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High capacity screening of pooled compounds: Identification of the active compound without re-assay of pool members by Devlin, James J., Liang, Amy, Trinh, Lan, Polokoff, Mark A., Senator, David, Zheng, Wei, Kondracki, Jason, Kretschmer, Peter J., Morser, John, Lipson, Samuel E., Spann, Richard, Loughlin, John A., Dunn, Kathryn V., Morrissey, Michael M.

“…A matrix‐based compound pooling and deconvolution method has been developed that significantly increased the efficiency of a high‐capacity screening program…”
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Genomic organization of the human HBNF gene and characterization of an HBNF variant protein as a splice mutant by Kretschmer, P J, Fairhurst, J L, Hulmes, J D, Popjes, M L, Böhlen, P, Kovesdi, I

“…The organization of the human heparin-binding neurite outgrowth promoting factor (HBNF) gene is presented. Based on Southern analysis and the isolation of…”
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Structure of the gene coding for the human retinoic acid-inducible factor, MK by Fairhurst, J L, Kretschmer, P J, Kovacs, E, Böhlen, P, Kovesdi, I

“…The retinoic acid-inducible MK gene shows a distinct developmental pattern of expression, which implies that it has potential growth regulation and…”
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Replication and Expression of Thymidine Kinase and Human Globin Genes Microinjected into Mouse Fibroblasts by Anderson, W. French, Killos, Lillian, Sanders-Haigh, Linda, Kretschmer, Peter J., Diacumakos, Elaine G.

“…A mixture of two recombinant plasmids was microinjected into mouse thymidine kinase-negative fibroblasts (L cells). One plasmid contained the thymidine kinase…”
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Advertised meeting-the-competition clauses: collusion instead of price discrimination by Budzinski, Oliver, Kretschmer, Jürgen-Peter

“…Pricing strategies may include the advertising of meeting-the-competition clauses (MCCs). We show in a specific spatial model scenario with differently…”
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