Search Results - "KRESTY, Laura A"

Cranberry Polyphenols in Esophageal Cancer Inhibition: New Insights by Weh, Katherine M, Zhang, Yun, Howard, Connor L, Howell, Amy B, Clarke, Jennifer L, Kresty, Laura A

“…Esophageal adenocarcinoma (EAC) is a cancer characterized by rapidly rising incidence and poor survival, resulting in the need for new prevention and treatment…”
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Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model by Zhang, Yun, Weh, Katherine M, Tripp, Bridget A, Clarke, Jennifer L, Howard, Connor L, Sunilkumar, Shruthi, Howell, Amy B, Kresty, Laura A

“…We recently reported that cranberry proanthocyanidins (C-PACs) inhibit esophageal adenocarcinoma (EAC) by 83% through reversing reflux-induced bacterial,…”
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Cranberries and Cancer: An Update of Preclinical Studies Evaluating the Cancer Inhibitory Potential of Cranberry and Cranberry Derived Constituents by Weh, Katherine M, Clarke, Jennifer, Kresty, Laura A

“…Cranberries are rich in bioactive constituents reported to influence a variety of health benefits, ranging from improved immune function and decreased…”
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Disparities in Head and Neck Cancer: A Case for Chemoprevention with Vitamin D by Ibrahimovic, Mirela, Franzmann, Elizabeth, Mondul, Alison M, Weh, Katherine M, Howard, Connor, Hu, Jennifer J, Goodwin, W Jarrard, Kresty, Laura A

“…Blacks experience disproportionate head and neck cancer (HNC) recurrence and mortality compared to Whites. Overall, vitamin D status is inversely associated to…”
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Characterizing isoform switching events in esophageal adenocarcinoma by Zhang, Yun, Weh, Katherine M., Howard, Connor L., Riethoven, Jean-Jack, Clarke, Jennifer L., Lagisetty, Kiran H., Lin, Jules, Reddy, Rishindra M., Chang, Andrew C., Beer, David G., Kresty, Laura A.

“…Isoform switching events with predicted functional consequences are common in many cancers, but characterization of switching events in esophageal…”
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Immune determinants of Barrett's progression to esophageal adenocarcinoma by Lagisetty, Kiran H, McEwen, Dyke P, Nancarrow, Derek J, Schiebel, Johnathon G, Ferrer-Torres, Daysha, Ray, Dipankar, Frankel, Timothy L, Lin, Jules, Chang, Andrew C, Kresty, Laura A, Beer, David G

“…Esophageal adenocarcinoma (EAC) develops from Barrett's esophagus (BE), a chronic inflammatory state that can progress through a series of transformative…”
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Cranberry proanthocyanidins mediate growth arrest of lung cancer cells through modulation of gene expression and rapid induction of apoptosis by Kresty, Laura A, Howell, Amy B, Baird, Maureen

“…Cranberries are rich in bioactive constituents purported to enhance immune function, improve urinary tract health, reduce cardiovascular disease and more…”
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Cranberry Proanthocyanidins Induce Apoptosis and Inhibit Acid-Induced Proliferation of Human Esophageal Adenocarcinoma Cells by Kresty, Laura A, Howell, Amy B, Baird, Maureen

“…The occurrence of esophageal adenocarcinoma and its only recognized precursor lesion, Barrett’s esophagus, has rapidly increased during the past three decades…”
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Effects of a Topically Applied Bioadhesive Berry Gel on Loss of Heterozygosity Indices in Premalignant Oral Lesions by SHUMWAY, Brian S, KRESTY, Laura A, LARSEN, Peter E, ZWICK, Jared C, BO LU, FIELDS, Henry W, MUMPER, Russell J, STONER, Gary D, MALLERY, Susan R

“…Purpose: The aim of this study was to assess the effects of topical application of a 10% (w/w) freeze-dried black raspberry (FBR) gel on oral intraepithelial…”
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Mitochondria-targeted magnolol inhibits OXPHOS, proliferation, and tumor growth via modulation of energetics and autophagy in melanoma cells by Cheng, Gang, Hardy, Micael, Zielonka, Jacek, Weh, Katherine, Zielonka, Monika, Boyle, Kathleen A., Abu Eid, Mahmoud, McAllister, Donna, Bennett, Brian, Kresty, Laura A., Dwinell, Michael B., Kalyanaraman, Balaraman

“…•Mito-magnolol is nearly 100-fold more effective than magnolol.•Mito-magnolol inhibits mitochondrial respiration and melanoma cell proliferation.•Mito-magnolol…”
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Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPKα signaling in STK11 mutant lung cancer by Chen, Xiuyuan, Mao, Rui, Su, Wenmei, Yang, Xia, Geng, Qianqian, Guo, Chunfang, Wang, Zhuwen, Wang, Jun, Kresty, Laura A., Beer, David G., Chang, Andrew C., Chen, Guoan

“…The role of circular RNA in cancer is emerging. A newly reported circular RNA HIPK3 (circHIPK3) is critical in cell proliferation of various cancer types,…”
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Expression, modulation, and clinical correlates of the autophagy protein Beclin-1 in esophageal adenocarcinoma by Weh, Katherine M., Howell, Amy B., Kresty, Laura A.

“…Esophageal adenocarcinoma (EAC) is characterized by rapidly increasing incidence and mortality rates and poor survival. Efficacious preventive and treatment…”
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Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis by TONG CHEN, NINES, Ronald G, PESCHKE, Sarah M, KRESTY, Laura A, STONER, Gary D

“…The inducible nitric oxide synthase (iNOS) generates a high concentration of nitric oxide (NO) in tissues. Increased NO production is associated with many…”
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In situ Assessment of Intraepithelial Neoplasia in Hamster Trachea Epithelium Using Angle-Resolved Low-Coherence Interferometry by CHALUT, Kevin J, KRESTY, Laura A, PYHTILA, John W, NINES, Ronald, BAIRD, Maureen, STEELE, Vemon E, WAX, Adam

“…Optical spectroscopy was used to evaluate the transformation of nuclear morphology associated with intraepithelial neoplasia in an animal model of…”
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Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation by Kresty, Laura A, Weh, Katherine M, Zeyzus-Johns, Bree, Perez, Laura N, Howell, Amy B

“…Cranberries are rich in bioactive constituents known to improve urinary tract health and more recent evidence supports cranberries possess cancer inhibitory…”
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The role of nutrition in influencing mechanisms involved in environmentally mediated diseases by Hennig, Bernhard, Petriello, Michael C, Gamble, Mary V, Surh, Young-Joon, Kresty, Laura A, Frank, Norbert, Rangkadilok, Nuchanart, Ruchirawat, Mathuros, Suk, William A

“…Human exposure to environmental contaminants such as persistent chlorinated organics, heavy metals, pesticides, phthalates, flame retardants, electronic waste…”
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Proanthocyanidins mitigate bile acid‐induced changes in GSTT2 levels in a panel of racially diverse patient‐derived primary esophageal cell cultures by Weh, Katherine M., Turgeon, Danielle K., Rubenstein, Joel H., Clarke, Jennifer L., Howell, Amy B., Chang, Andrew C., Kresty, Laura A.

“…Persistent and symptomatic reflux of gastric and duodenal contents, known as gastroesophageal reflux disease (GERD), is the strongest risk factor for…”
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Constitutively Higher Level of GSTT2 in Esophageal Tissues From African Americans Protects Cells Against DNA Damage by Ferrer-Torres, Daysha, Nancarrow, Derek J., Steinberg, Hannah, Wang, Zhuwen, Kuick, Rork, Weh, Katherine M., Mills, Ryan E., Ray, Dipankar, Ray, Paramita, Lin, Jules, Chang, Andrew C., Reddy, Rishindra M., Orringer, Mark B., Canto, Marcia I., Shaheen, Nicholas J., Kresty, Laura A., Chak, Amitabh, Wang, Thomas D., Rubenstein, Joel H., Beer, David G.

“…African American and European American individuals have a similar prevalence of gastroesophageal reflux disease (GERD), yet esophageal adenocarcinoma (EAC)…”
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A phase I pilot study evaluating the beneficial effects of black raspberries in patients with Barrett's esophagus by Kresty, Laura A, Fromkes, John J, Frankel, Wendy L, Hammond, Cynthia D, Seeram, Navindra P, Baird, Maureen, Stoner, Gary D

“…Black raspberries inhibit a broad range of cancers in preclinical models which has led to clinical evaluations targeting premalignant lesions of the colon,…”
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Frequent Alterations of p16INK4a and p14ARF in Oral Proliferative Verrucous Leukoplakia by Kresty, Laura A, Mallery, Susan R, Knobloch, Thomas J, Li, Junan, Lloyd, Mary, Casto, Bruce C, Weghorst, Christopher M

“…Proliferative verrucous leukoplakia (PVL) represents a rare but highly aggressive form of oral leukoplakia with >70% progressing to malignancy. Yet, PVL…”
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