Search Results - "KREN, Vladimir"

Chirality Matters: Biological Activity of Optically Pure Silybin and Its Congeners by Křen, Vladimír

“…This review focuses on the specific biological effects of optically pure silymarin flavo-nolignans, mainly silybins A and B, isosilybins A and B, silychristins…”
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Biocatalytic production of mandelic acid and analogues: a review and comparison with chemical processes by Martínková, Ludmila, Kren, Vladimír

“…The aim of this study is to summarize the current progress in the design of biocatalytic processes applicable for the production of optically pure mandelic…”
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Galectin–Carbohydrate Interactions in Biomedicine and Biotechnology by Laaf, Dominic, Bojarová, Pavla, Elling, Lothar, Křen, Vladimír

“…Cellular communication events are mediated by interactions between cell-surface sugars and lectins, which are carbohydrate-binding proteins. Galectins are…”
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Isoquercitrin: Pharmacology, toxicology, and metabolism by Valentová, Kateřina, Vrba, Jiří, Bancířová, Martina, Ulrichová, Jitka, Křen, Vladimír

“…[Display omitted] •Isoquercitrin=quercetin-3-O-glucoside=quercetin-3-O-β-d-glucopyranoside.•Isoquercitrin can be obtained by enzymatic hydrolysis of…”
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Rutinosidase and other diglycosidases: Rising stars in biotechnology by Křen, Vladimír, Bojarová, Pavla

“…Diglycosidases are a special class of glycosidases (EC 3.2.1) that catalyze the separation of intact disaccharide moieties from the aglycone part. The main…”
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Silybin and silymarin--new and emerging applications in medicine by Gazák, Radek, Walterová, Daniela, Kren, Vladimír

“…This review critically surveys the literature published mainly within this millennium on the new and emerging applications of silybin (pure, chemically defined…”
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Biotransformations with nitrilases by Martínková, Ludmila, Křen, Vladimír

“…The range of possible nitrilase applications has been recently broadened but in most cases the parameters of the reactions need to be improved to establish…”
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β-N-Acetylhexosaminidases—the wizards of glycosylation by Bojarová, Pavla, Bruthans, Jan, Křen, Vladimír

“…β- N -Acetylhexosaminidases (EC 3.2.1.52) are a unique family of glycoside hydrolases with dual substrate specificity and a particular reaction mechanism…”
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Silybin and its congeners: from traditional medicine to molecular effects by Křen, Vladimír, Valentová, Kateřina

“…Covering: 2015 up to 2022 (Feb)Silymarin, an extract of milk thistle ( ) fruits, has been used in various medicinal applications since ancient times. A major…”
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Mild and Selective Method of Bromination of Flavonoids by Hurtová, Martina, Biedermann, David, Kuzma, Marek, Křen, Vladimír

“…A new method was developed for the mild and selective bromination of simple aromatic compounds and flavonoids in good yields using α,β-dibromohydrocinnamic…”
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Biodegradation potential of the genus Rhodococcus by MARTINKOVA, Ludmila, UHNAKOVA, Bronislava, PATEK, Miroslav, NESVERA, Jan, KREN, Vladimir

“…A large number of aromatic compounds and organic nitriles, the two groups of compounds covered in this review, are intermediates, products, by-products or…”
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A Career in Biocatalysis: Kurt Faber by Křen, Vladimir, Kroutil, Wolfgang, Hall, Mélanie

“…Kurt Faber, a synthetic organic chemist by training, strongly influenced the field of biocatalysis throughout the course of his four-decade career (from the…”
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Glycosidases: a key to tailored carbohydrates by BOJAROVA, Pavla, KREN, Vladimir

“…In recent years, carbohydrate-processing enzymes have become the enzymes of choice in many applications thanks to their stereoselectivity and efficiency. This…”
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Laccases and Tyrosinases in Organic Synthesis by Martínková, Ludmila, Křístková, Barbora, Křen, Vladimír

“…Laccases (Lac) and tyrosinases (TYR) are mild oxidants with a great potential in research and industry. In this work, we review recent advances in their use in…”
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Methods of in vitro study of galectin-glycomaterial interaction by Heine, Viktoria, Dey, Carina, Bojarová, Pavla, Křen, Vladimír, Elling, Lothar

“…Galectins are a family of carbohydrate-binding lectins modulating cell events such as cell proliferation, apoptosis, adhesion or migration by cross-linking the…”
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Sweet antibiotics - the role of glycosidic residues in antibiotic and antitumor activity and their randomization by KREN, Vladimir, REZANKA, Tomas

“…A large number of antibiotics are glycosides. In numerous cases the glycosidic residues are crucial to their activity; sometimes, glycosylation only improves…”
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Recent trends in the treatment of cyanide-containing effluents: Comparison of different approaches by Martínková, Ludmila, Bojarová, Pavla, Sedova, Anastasia, Křen, Vladimír

“…The cyanide-containing effluents originate from, e.g., mining, coking, electroplating and chemical syntheses. The form and concentration of cyanide, and the…”
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The silymarin composition… and why does it matter??? by Chambers, Christopher Steven, Holečková, Veronika, Petrásková, Lucie, Biedermann, David, Valentová, Kateřina, Buchta, Martin, Křen, Vladimír

“…The extract from milk thistle (Silybum marianum (L.) Gaertn. (Asteraceae)), known as silymarin, contains a variety of flavonolignans and displays antioxidant,…”
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New Bacterial Aryl Sulfotransferases: Effective Tools for Sulfation of Polyphenols by Brodsky, Katerina, Petránková, Barbora, Petrásková, Lucie, Pelantová, Helena, Křen, Vladimír, Valentová, Kateřina, Bojarová, Pavla

“…The preparation of pure metabolites of bioactive compounds, particularly (poly)­phenols, is essential for the accurate determination of their pharmacological…”
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Defying Multidrug Resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans by Chambers, Christopher S, Viktorová, Jitka, Řehořová, Kateřina, Biedermann, David, Turková, Lucie, Macek, Tomáš, Křen, Vladimír, Valentová, Kateřina

“…Multidrug resistance (MDR) is a major challenge for the 21th century in both cancer chemotherapy and antibiotic treatment of bacterial infections. Efflux pumps…”
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