Search Results - "KREIL, Sebastian"

Functional imaging with dual-energy computed tomography for supplementary non-invasive assessment of mast cell burden in systemic mastocytosis by Riffel, Julia, Lübke, Johannes, Naumann, Nicole, Kreil, Sebastian, Metzgeroth, Georgia, Fabarius, Alice, Sotlar, Karl, Horny, Hans-Peter, Jawhar, Mohamad, Overhoff, Daniel, Schoenberg, Stefan, Hofmann, Wolf-Karsten, Henzler, Thomas, Schwaab, Juliana, Reiter, Andreas, Riffel, Philipp

“…Systemic mastocytosis (SM) is characterized by multifocal accumulation of neoplastic mast cells (MCs), predominately affecting the bone marrow (BM). Imaging…”
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Adverse Prognostic Impact of the KIT D816V Transcriptional Activity in Advanced Systemic Mastocytosis by Naumann, Nicole, Lübke, Johannes, Baumann, Sofie, Schwaab, Juliana, Hoffmann, Oliver, Kreil, Sebastian, Dangelo, Vito, Reiter, Lukas, Bugert, Peter, Kristensen, Thomas, Sotlar, Karl, Haselmann, Verena, Schneider, Sven, Metzgeroth, Georgia, Weiss, Christel, Popp, Henning D, Fabarius, Alice, Hofmann, Wolf-Karsten, Cross, Nicholas C P, Reiter, Andreas, Jawhar, Mohamad

“…In systemic mastocytosis (SM), qualitative and serial quantitative assessment of the D816V mutation is of diagnostic and prognostic relevance. We investigated…”
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Multidrug‐resistant organisms in allogeneic hematopoietic cell transplantation by Heidenreich, Daniela, Kreil, Sebastian, Nolte, Florian, Hofmann, Wolf K., Miethke, Thomas, Klein, Stefan A.

“…Objective Multidrug‐resistant organisms (MDRO) are a challenge in allogeneic hematopoietic cell transplantation (HCT). However, in the literature there is no…”
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Somatic Diseases in Child Survivors of the Holocaust With Posttraumatic Stress Disorder: A Comparative Study by Sperling, Wolfgang, Kreil, Sebastian, Biermann, Teresa

“…ABSTRACTThe incidence of mental and somatic sequelae has been shown to be very high in people who survived the Holocaust. In the current study, 80 Holocaust…”
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Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib by Ernst, Thomas, Erben, Philipp, Muller, Martin C, Paschka, Peter, Schenk, Thomas, Hoffmann, Jana, Kreil, Sebastian, La Rosee, Paul, Hehlmann, Rudiger, Hochhaus, Andreas

“…III. Medizinische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Germany Correspondence: Andreas Hochhaus, III. Medizinische…”
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Dynamics of mutant BCR-ABL-positive clones after cessation of tyrosine kinase inhibitor therapy by HANFSTEIN, Benjamin, MÜLLER, Martin C, KREIL, Sebastian, ERNST, Thomas, SCHENK, Thomas, LORENTZ, Christian, SCHWINDEL, Uwe, LEITNER, Armin, HEHLMANN, Rudiger, HOCHHAUS, Andreas

“…Point mutations of the BCR-ABL tyrosine kinase domain are considered the predominant cause of imatinib resistance in chronic myeloid leukemia. The expansion of…”
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A polymorphism associated with STAT3 expression and response of chronic myeloid leukemia to interferon α by KREIL, Sebastian, WAGHORN, Katherine, ERNST, Thomas, CHASE, Andrew, WHITE, Helen, HEHLMANN, Rüdiger, REITER, Andreas, HOCHHAUS, Andreas, CROSS, Nicholas C. P

“…Interferon alpha (IFN) induces variable responses in chronic myeloid leukemia (CML), with 8-30% of early chronic phase cases achieving a complete cytogenetic…”
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Perfusion Imaging with SPECT in the Era of Pathophysiology-Based Biomarkers for Alzheimer's Disease by Degirmenci, Ümüt, Lewczuk, Piotr, Weih, Markus, Kuwert, Torsten, Kornhuber, Johannes, Schmidt, Daniela, Kreil, Sebastian

“…SPECT allows registration of regional cerebral blood flow (rCBF) which is altered in a characteristic temporoparietal pattern in Alzheimer's Dementia. Numerous…”
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Prospective analysis of the attendance behaviour of the participants of a facilitated support group for patients after allogeneic hematopoietic cell transplantation by Geeck, Karsten, Kreil, Sebastian, Hausmann, Michaela, Hofmann, Wolf-Karsten, Heidenreich, Daniela, Klein, Stefan A.

“…Purpose Support groups might help survivors of allogeneic hematopoietic cell transplantations (HCT) to cope with medical, psychological, and social challenges…”
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Superior Efficacy of Midostaurin Over Cladribine in Advanced Systemic Mastocytosis: A Registry-Based Analysis by Lübke, Johannes, Schwaab, Juliana, Naumann, Nicole, Horny, Hans-Peter, Weiß, Christel, Metzgeroth, Georgia, Kreil, Sebastian, Cross, Nicholas C P, Sotlar, Karl, Fabarius, Alice, Hofmann, Wolf-Karsten, Valent, Peter, Gotlib, Jason, Jawhar, Mohamad, Reiter, Andreas

“…On the basis of data from the German Registry on Disorders of Eosinophils and Mast Cells, we compared the efficacy of midostaurin and cladribine in patients…”
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Response and Resistance to Cladribine in Patients with Advanced Systemic Mastocytosis: A Registry-Based Analysis by Lübke, Johannes, Naumann, Nicole, Kreil, Sebastian, Metzgeroth, Georgia, Horny, Hans-Peter, Sotlar, Karl, Cross, Nicholas C.P., Fabarius, Alice, Valent, Peter, Hofmann, Wolf-Karsten, Schwaab, Juliana, Reiter, Andreas

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Antibody Response to Vaccination with BNT162b2, mRNA-1273, and ChADOx1 in Patients with Myeloid and Lymphoid Neoplasms by Rotterdam, Jil, Thiaucourt, Margot, Schwaab, Juliana, Reiter, Andreas, Kreil, Sebastian, Steiner, Laurenz, Popp, Henning D., Hofmann, Wolf-Karsten, Bonatz, Karin, Gerhards, Catharina, Neumaier, Michael, Jawhar, Mohamad, Saussele, Susanne

“…Background: In general, patients with hematological diseases are predisposed to develop infections. Severe COVID-19 infection associated with high mortality is…”
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Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions: reevaluation of the defining characteristics in a registry-based cohort by Metzgeroth, Georgia, Steiner, Laurenz, Naumann, Nicole, Lübke, Johannes, Kreil, Sebastian, Fabarius, Alice, Haferlach, Claudia, Haferlach, Torsten, Hofmann, Wolf-Karsten, Cross, Nicholas C. P., Schwaab, Juliana, Reiter, Andreas

“…In a registry-based analysis of 135 patients with “myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions” (MLN-TK; FIP1L1::PDGFRA , n …”
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Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms by Grand, Francis H., Hidalgo-Curtis, Claire E., Ernst, Thomas, Zoi, Katerina, Zoi, Christine, McGuire, Carolann, Kreil, Sebastian, Jones, Amy, Score, Joannah, Metzgeroth, Georgia, Oscier, David, Hall, Andrew, Brandts, Christian, Serve, Hubert, Reiter, Andreas, Chase, Andrew J., Cross, Nicholas C.P.

“…Recent evidence has demonstrated that acquired uniparental disomy (aUPD) is a novel mechanism by which pathogenetic mutations in cancer may be reduced to…”
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Clinicohematologic and Molecular Response of Essential Thrombocythemia Patients Treated with Pegylated Interferon-Alpha: A Multicenter Study on Behalf of the German Study Group-MPN (GSG-MPN) by Stegelmann, Frank, Teichmann, Lino L., Heidel, Florian H., Crodel, Carl C., Ernst, Thomas, Kreil, Sebastian, Reiter, Andreas, Otten, Sara, Schauer, Stefanie, Körber, Ruth-Miriam, Kricheldorf, Kim, Isfort, Susanne, Döhner, Hartmut, Brümmendorf, Tim H., Griesshammer, Martin, Döhner, Konstanze, Koschmieder, Steffen

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The insertion site is the main risk factor for central venous catheter‐related complications in patients with hematologic malignancies by Heidenreich, Daniela, Hansen, Eleonore, Kreil, Sebastian, Nolte, Florian, Jawhar, Mohamad, Hecht, Anna, Hofmann, Wolf‐Karsten, Klein, Stefan A.

“…Central venous catheters (CVC) placed either via the internal jugular vein (IJV) or the subclavian vein (SCV) are routinely used in patients with hematologic…”
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Clinicohematologic and molecular response of essential thrombocythemia patients treated with pegylated interferon-α: a multi-center study of the German Study Group-Myeloproliferative Neoplasms (GSG-MPN) by Stegelmann, Frank, Teichmann, Lino L., Heidel, Florian H., Crodel, Carl C., Ernst, Thomas, Kreil, Sebastian, Reiter, Andreas, Otten, Sara, Schauer, Stefanie, Körber, Ruth-Miriam, Kricheldorf, Kim, Isfort, Susanne, Döhner, Hartmut, Brümmendorf, Tim H., Griesshammer, Martin, Döhner, Konstanze, Koschmieder, Steffen

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Hematopoietic stem-cell transplantation for advanced systemic mastocytosis by Ustun, Celalettin, Reiter, Andreas, Scott, Bart L, Nakamura, Ryotaro, Damaj, Gandhi, Kreil, Sebastian, Shanley, Ryan, Hogan, William J, Perales, Miguel-Angel, Shore, Tsiporah, Baurmann, Herrad, Stuart, Robert, Gruhn, Bernd, Doubek, Michael, Hsu, Jack W, Tholouli, Eleni, Gromke, Tanja, Godley, Lucy A, Pagano, Livio, Gilman, Andrew, Wagner, Eva Maria, Shwayder, Tor, Bornhäuser, Martin, Papadopoulos, Esperanza B, Böhm, Alexandra, Vercellotti, Gregory, Van Lint, Maria Teresa, Schmid, Christoph, Rabitsch, Werner, Pullarkat, Vinod, Legrand, Faezeh, Yakoub-Agha, Ibrahim, Saber, Wael, Barrett, John, Hermine, Olivier, Hagglund, Hans, Sperr, Wolfgang R, Popat, Uday, Alyea, Edwin P, Devine, Steven, Deeg, H Joachim, Weisdorf, Daniel, Akin, Cem, Valent, Peter

“…Advanced systemic mastocytosis (SM), a fatal hematopoietic malignancy characterized by drug resistance, has no standard therapy. The effectiveness of…”
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Clinical and histopathological features of myeloid neoplasms with concurrent Janus kinase 2 (JAK2) V617F and KIT proto‐oncogene, receptor tyrosine kinase (KIT) D816V mutations by Naumann, Nicole, Lübke, Johannes, Shomali, William, Reiter, Lukas, Horny, Hans‐Peter, Jawhar, Mohamad, Dangelo, Vito, Fabarius, Alice, Metzgeroth, Georgia, Kreil, Sebastian, Sotlar, Karl, Oni, Claire, Harrison, Claire, Hofmann, Wolf‐Karsten, Cross, Nicholas C. P., Valent, Peter, Radia, Deepti, Gotlib, Jason, Reiter, Andreas, Schwaab, Juliana

“…Summary We report on 45 patients with myeloid neoplasms and concurrent Janus kinase 2 (JAK2) V617F and KIT proto‐oncogene, receptor tyrosine kinase (KIT) D816V…”
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Response and resistance to cladribine in patients with advanced systemic mastocytosis: a registry-based analysis by Lübke, Johannes, Naumann, Nicole, Metzgeroth, Georgia, Kreil, Sebastian, Brand, Timo, Horny, Hans-Peter, Sotlar, Karl, Cross, Nicholas C. P., Fabarius, Alice, Valent, Peter, Hofmann, Wolf-Karsten, Reiter, Andreas, Schwaab, Juliana

“…We sought to evaluate the efficacy of the purine analogue cladribine in 79 patients with advanced systemic mastocytosis (AdvSM) using data from the ‘German…”
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