Search Results - "KREIDBERG, Jordan A"

GSK3β and the aging kidney by Kreidberg, Jordan A, Schumacher, Valerie A

“…Kidney function decreases with age and may soon limit millions of lives as the proportion of the population over 70 years of age increases. Glycogen synthase…”
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Development of the renal glomerulus: good neighbors and good fences by Quaggin, Susan E, Kreidberg, Jordan A

“…The glomerulus of the mammalian kidney is an intricate structure that contains an unusual filtration barrier that retains higher molecular weight proteins and…”
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Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms by Kann, Martin, Ettou, Sandrine, Jung, Youngsook L, Lenz, Maximilian O, Taglienti, Mary E, Park, Peter J, Schermer, Bernhard, Benzing, Thomas, Kreidberg, Jordan A

“…The transcription factor Wilms' tumor suppressor 1 (WT1) is key to podocyte development and viability; however, WT1 transcriptional networks in podocytes…”
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Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury by HO, Jacqueline, KAR HUI NG, ROSEN, Seymour, DOSTAL, Ales, GREGORY, Richard I, KREIDBERG, Jordan A

“…MicroRNAs (miRNAs) are in a class of endogenous, small, noncoding RNAs that exert their effects through posttranscriptional repression of specific target…”
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WT1 and kidney progenitor cells by Kreidberg, Jordan A.

“…Kidney development has been studied over the past sixty years as a model of embryonic induction during organogenesis. Wilms' tumor-1 (WT1), that encodes a…”
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Dicer function is required in the metanephric mesenchyme for early kidney development by Chu, Jessica Y S, Sims-Lucas, Sunder, Bushnell, Daniel S, Bodnar, Andrew J, Kreidberg, Jordan A, Ho, Jacqueline

“…MicroRNAs (miRNAs) are small, noncoding regulatory RNAs that act as posttranscriptional repressors by binding to the 3'-untranslated region (3'-UTR) of target…”
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Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease by Qin, Shan, Taglienti, Mary, Nauli, Surya M, Contrino, Leah, Takakura, Ayumi, Zhou, Jing, Kreidberg, Jordan A

“…Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder that is caused by mutations at two loci, polycystin 1 (PKD1) and polycystin…”
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Coordinate integrin and c-Met signaling regulate Wnt gene expression during epithelial morphogenesis by Liu, Yingjie, Chattopadhyay, Nibedita, Qin, Shan, Szekeres, Charles, Vasylyeva, Tetyana, Mahoney, Zhen X, Taglienti, Mary, Bates, Carlton M, Chapman, Harold A, Miner, Jeffrey H, Kreidberg, Jordan A

“…Integrin receptors for the extracellular matrix and receptor tyrosine kinase growth factor receptors represent two of the major families of receptors that…”
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Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa by Gao, Xiaobo, Chen, Xing, Taglienti, Mary, Rumballe, Bree, Little, Melissa H, Kreidberg, Jordan A

“…Most studies on kidney development have considered the interaction of the metanephric mesenchyme and the ureteric bud to be the major inductive event that…”
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Palmitoylation of tetraspanin proteins: modulation of CD151 lateral interactions, subcellular distribution, and integrin-dependent cell morphology by Yang, Xiuwei, Claas, Christoph, Kraeft, Stine-Kathrein, Chen, Lan Bo, Wang, Zemin, Kreidberg, Jordan A, Hemler, Martin E

“…Here we demonstrate that multiple tetraspanin (transmembrane 4 superfamily) proteins are palmitoylated, in either the Golgi or a post-Golgi compartment. Using…”
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Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche by Langsdorf, Aliete, Schumacher, Valerie, Shi, Xiaofeng, Tran, Thanh, Zaia, Joseph, Jain, Sanjay, Taglienti, Mary, Kreidberg, Jordan A, Fine, Alan, Ai, Xingbin

“…Glial cell line-derived neurotrophic factor (GDNF) is a heparan sulfate (HS)-binding factor. GDNF is produced by somatic Sertoli cells, where it signals to…”
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The LIM homeobox gene Lhx9 is essential for mouse gonad formation by Westphal, Heiner, Birk, Ohad S, Casiano, Delane E, Wassif, Christopher A, Cogliati, Tiziana, Zhao, Liping, Zhao, Yangu, Grinberg, Alexander, Huang, SingPing, Kreidberg, Jordan A, Parker, Keith L, Porter, Forbes D

“…During mammalian embryonic development, the ovaries and testes develop from somatic cells of the urogenital ridges as indifferent gonads, harbouring primordial…”
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Reelin, Integrin and Dab1 Interactions during Embryonic Cerebral Cortical Development by Schmid, Ralf S., Jo, Rebecca, Shelton, Stephanie, Kreidberg, Jordan A., Anton, E. S.

“…Extracellular matrix-like molecule reelin and cell surface adhesion receptors such as α3β1 integrin can regulate neuronal migration and position in the…”
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Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney by Taglienti, Mary, Graf, Daniel, Schumacher, Valerie, Kreidberg, Jordan A

“…The mammalian kidney is composed of thousands of nephrons that are formed through reiterative induction of a mesenchymal-to-epithelial transformation by a…”
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The Long and Short of MicroRNAs in the Kidney by HO, Jacqueline, KREIDBERG, Jordan A

“…MicroRNAs (miRNAs) are a group of small, noncoding RNAs that act as novel regulators of gene expression through the post-transcriptional repression of their…”
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Integrins in kidney development, function, and disease by Kreidberg, J A, Symons, J M

“…Integrins are heterodimeric cell surface receptors that mediate heterophilic cell-cell interactions and interactions between cells and the extracellular matrix…”
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Podocyte-Derived BMP7 Is Critical for Nephron Development by KAZAMA, Itsuro, MAHONEY, Zhen, MINER, Jeffrey H, GRAF, Daniel, ECONOMIDES, Aris N, KREIDBERG, Jordan A

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Epithelial cell α3β1 integrin links β-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis by Kim, Kevin K, Wei, Ying, Szekeres, Charles, Kugler, Matthias C, Wolters, Paul J, Hill, Marla L, Frank, James A, Brumwell, Alexis N, Wheeler, Sarah E, Kreidberg, Jordan A, Chapman, Harold A

“…Pulmonary fibrosis, in particular idiopathic pulmonary fibrosis (IPF), results from aberrant wound healing and scarification. One population of fibroblasts…”
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Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development by Hartwig, Sunny, Ho, Jacqueline, Pandey, Priyanka, Macisaac, Kenzie, Taglienti, Mary, Xiang, Michael, Alterovitz, Gil, Ramoni, Marco, Fraenkel, Ernest, Kreidberg, Jordan A

“…The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA- and RNA-binding protein that plays an essential role in nephron progenitor differentiation during renal…”
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Analysis of Netrin 1 receptors during inner ear development by Matilainen, Tanja, Haugas, Maarja, Kreidberg, Jordan A, Salminen, Marjo

“…Netrin 1 plays key roles in axon guidance and neuronal migration during central nervous system (CNS) development. Outside the CNS, Netrin 1 has been shown to…”
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