Search Results - "KRAUSE, Carola"
-
1
Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways
Published in The Journal of biological chemistry (31-12-2010)“…Sclerostin is expressed by osteocytes and has catabolic effects on bone. It has been shown to antagonize bone morphogenetic protein (BMP) and/or Wnt activity,…”
Get full text
Journal Article -
2
Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling
Published in Journal of bone and joint surgery. American volume (01-02-2008)Get full text
Conference Proceeding Journal Article -
3
Noggin
Published in The international journal of biochemistry & cell biology (01-04-2011)“…Metabologens initiate, promote and maintain morphogenesis and adult tissue homeostasis. Bone morphogenetic proteins (BMPs) which belong to the transforming…”
Get full text
Journal Article -
4
Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts
Published in Fibrogenesis & tissue repair (28-06-2011)“…Dupuytren's disease is a fibroproliferative disorder of the palmar fascia. The treatment used to date has mostly been surgery, but there is a high recurrence…”
Get full text
Journal Article -
5
Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity
Published in The Journal of biological chemistry (16-04-2010)“…Bone morphogenetic proteins (BMPs) are used clinically to induce new bone formation in spinal fusions and long bone non-union fractures. However, large amounts…”
Get full text
Journal Article -
6
Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling
Published in Journal of bone and joint surgery. American volume (01-02-2008)“…Sclerosteosis and Van Buchem disease are rare, high-bone-mass disorders that have been linked to deficiency in the SOST gene, encoding sclerostin. Sclerostin…”
Get full text
Journal Article -
7
Comprehensive analysis of TGF-β and BMP receptor interactomes
Published in European journal of cell biology (01-04-2012)“…An immense number of cellular processes are initiated by cell surface serine/threonine kinase receptors belonging to the TGF-β/BMP family. Subsequent…”
Get full text
Journal Article -
8
RGK Small GTP-binding Proteins Interact with the Nucleotide Kinase Domain of Ca2+-channel β-Subunits via an Uncommon Effector Binding Domain
Published in The Journal of biological chemistry (13-04-2007)“…RGK proteins (Kir/Gem, Rad, Rem, and Rem2) form a small subfamily of the Ras superfamily. Despite a conserved GTP binding core domain, several differences…”
Get full text
Journal Article -
9
Elevated transforming growth factor [beta] and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts
Published in Fibrogenesis & tissue repair (28-06-2011)“…Background Dupuytren's disease is a fibroproliferative disorder of the palmar fascia. The treatment used to date has mostly been surgery, but there is a high…”
Get full text
Journal Article -
10
RGK Small GTP-binding Proteins Interact with the Nucleotide Kinase Domain of Ca super(2+)-channel beta -Subunits via an Uncommon Effector Binding Domain
Published in The Journal of biological chemistry (01-04-2007)“…RGK proteins (Kir/Gem, Rad, Rem, and Rem2) form a small subfamily of the Ras superfamily. Despite a conserved GTP binding core domain, several differences…”
Get full text
Journal Article -
11
RGK Small GTP-binding Proteins Interact with the Nucleotide Kinase Domain of Ca2+-channel β-Subunits via an Uncommon Effector Binding Domain
Published in The Journal of biological chemistry (13-04-2007)“…RGK proteins (Kir/Gem, Rad, Rem, and Rem2) form a small subfamily of the Ras superfamily. Despite a conserved GTP binding core domain, several differences…”
Get full text
Journal Article -
12
Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling
Published in Journal of bone and joint surgery. American volume (2008)“…Sclerosteosis and Van Buchem disease are rare, high-bone-mass disorders that have been linked to deficiency in the SOST gene, encoding sclerostin. Sclerostin…”
Get full text
Journal Article