Search Results - "KRARUP, THURE"

Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes by Holst, Jens J, Knop, Filip K, Vilsbøll, Tina, Krarup, Thure, Madsbad, Sten

“…[...] the studies also demonstrate that common variants have a low impact on these parameters, and a clear genetic explanation for the loss of incretin effect…”
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Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial by Thomsen, Mads N., Skytte, Mads J., Samkani, Amirsalar, Carl, Martin H., Weber, Philip, Astrup, Arne, Chabanova, Elizaveta, Fenger, Mogens, Frystyk, Jan, Hartmann, Bolette, Holst, Jens J., Larsen, Thomas M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen B., Krarup, Thure

“…Aims/hypothesis Lifestyle modification and weight loss are cornerstones of type 2 diabetes management. However, carbohydrate restriction may have…”
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Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base by Feinman, Richard D., Ph.D, Pogozelski, Wendy K., Ph.D, Astrup, Arne, M.D, Bernstein, Richard K., M.D, Fine, Eugene J., M.S., M.D, Westman, Eric C., M.D., M.H.S, Accurso, Anthony, M.D, Frassetto, Lynda, M.D, Gower, Barbara A., Ph.D, McFarlane, Samy I., M.D, Nielsen, Jörgen Vesti, M.D, Krarup, Thure, M.D, Saslow, Laura, Ph.D, Roth, Karl S., M.D, Vernon, Mary C., M.D, Volek, Jeff S., R.D., Ph.D, Wilshire, Gilbert B., M.D, Dahlqvist, Annika, M.D, Sundberg, Ralf, M.D., Ph.D, Childers, Ann, M.D, Morrison, Katharine, M.R.C.G.P, Manninen, Anssi H., M.H.S, Dashti, Hussain M., M.D., Ph.D., F.A.C.S., F.I.C.S, Wood, Richard J., Ph.D, Wortman, Jay, M.D, Worm, Nicolai, Ph.D

“…Abstract The inability of current recommendations to control the epidemic of diabetes, the specific failure of the prevailing low-fat diets to improve obesity,…”
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A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients by Samkani, Amirsalar, Skytte, Mads J., Kandel, Daniel, Kjaer, Stine, Astrup, Arne, Deacon, Carolyn F., Holst, Jens J., Madsbad, Sten, Rehfeld, Jens F., Haugaard, Steen B., Krarup, Thure

“…The aim of the study was to assess whether a simple substitution of carbohydrate in the conventionally recommended diet with protein and fat would result in a…”
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Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet by Alzahrani, Ahmad H., Skytte, Mads J., Samkani, Amirsalar, Thomsen, Mads N., Astrup, Arne, Ritz, Christian, Chabanova, Elizaveta, Frystyk, Jan, Holst, Jens J., Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen B., Krarup, Thure, Larsen, Thomas Meinert, Magkos, Faidon

“…Purpose We previously reported beneficial glucoregulatory effects of a fully provided carbohydrate-reduced, high-protein (CRHP) diet in patients with type 2…”
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Effect of Metformin vs. Placebo in Combination with Insulin Analogues on Bone Markers P1NP and CTX in Patients with Type 2 Diabetes Mellitus by Nordklint, Azra Karahasanovic, Almdal, Thomas Peter, Vestergaard, Peter, Lundby-Christensen, Louise, Jørgensen, Niklas Rye, Boesgaard, Trine W., Breum, Leif, Gade-Rasmussen, Birthe, Sneppen, Simone B., Gluud, Christian, Hemmingsen, Bianca, Krarup, Thure, Madsbad, Sten, Mathiesen, Elisabeth R., Perrild, Hans, Tarnow, Lise, Thorsteinsson, Birger, Vestergaard, Henrik, Lund, Søren S., Eiken, Pia

“…Preclinical studies have shown a potential osteoanabolic effect of metformin but human studies of how metformin affects bone turnover are few. A post hoc…”
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Effects of a carbohydrate-reduced high-protein diet delivered with meal kits to Danish people with type 2 diabetes: protocol for a 12-month randomised controlled trial by Kopp, Luise H P, Søgaard-Hansen, Christina M, Zachhau, Karen M, Bastkjær, Rasmus M, Andersen, Barbara V, Budtz-Jørgensen, Esben, Byrne, Derek V, Chaaban, Nora, Holst, Jens J, Klindt, Trine B, Magkos, Faidon, Ozenne, Brice, Samkani, Amirsalar, Skytte, Mads J, Madsbad, Sten, Krarup, Thure, Thomsen, Mads N

“…IntroductionThe cornerstone in the management of type 2 diabetes (T2D) is lifestyle modification including a healthy diet, typically one in which carbohydrate…”
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Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects by Vilsbøll, Tina, Krarup, Thure, Madsbad, Sten, Holst, Jens J.

“…Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are both incretin hormones regulating postprandial insulin secretion…”
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Effects of Carbohydrate Restriction on Body Weight and Glycemic Control in Individuals with Type 2 Diabetes: A Randomized Controlled Trial of Efficacy in Real-Life Settings by Weber, Philip, Thomsen, Mads N, Skytte, Mads Juul, Samkani, Amirsalar, Carl, Martin Hansen, Astrup, Arne, Frystyk, Jan, Holst, Jens J, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, Thure, Haugaard, Steen B

“…A fully provided, hypocaloric, carbohydrate-reduced high-protein (CRHP) diet compared to a hypocaloric conventional diabetes (CD) diet for 6 weeks improved…”
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Reduced Postprandial Concentrations of Intact Biologically Active Glucagon-Like Peptide 1 in Type 2 Diabetic Patients by VILSBØLL, Tina, KRARUP, Thure, DEACON, Carolyn F, MADSBAD, Sten, HOLST, Jens J

“…Reduced Postprandial Concentrations of Intact Biologically Active Glucagon-Like Peptide 1 in Type 2 Diabetic Patients Tina Vilsbøll 1 2 , Thure Krarup 1 ,…”
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Effects of a Self-Prepared Carbohydrate-Reduced High-Protein Diet on Cardiovascular Disease Risk Markers in Patients with Type 2 Diabetes by Alzahrani, Ahmad H, Skytte, Mads J, Samkani, Amirsalar, Thomsen, Mads N, Astrup, Arne, Ritz, Christian, Frystyk, Jan, Holst, Jens J, Madsbad, Sten, Haugaard, Steen B, Krarup, Thure, Larsen, Thomas M, Magkos, Faidon

“…We previously observed beneficial effects of a carbohydrate-reduced, high-protein (CRHP) diet on cardiovascular risk markers in patients with type 2 diabetes…”
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Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials by Madsbad, Sten, Krarup, Thure, Deacon, Carolyn F, Holst, Jens J

“…PURPOSE OF REVIEWTo discus the virtues and shortcomings of the glucagon-like peptide-1 receptor agonists and the dipeptidyl peptidase-4 inhibitors in the…”
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Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects by Samkani, Amirsalar, Skytte, Mads J, Thomsen, Mads N, Astrup, Arne, Deacon, Carolyn F, Holst, Jens J, Madsbad, Sten, Rehfeld, Jens F, Krarup, Thure, Haugaard, Steen B

“…Postprandial responses to food are highly dependent on the macronutrient composition of the diet. We investigated the acute effects of transition from the…”
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Prevalence of interarm blood pressure difference is notably higher in women; the Viborg population-based screening program (VISP) by Dahl, Marie, Andersen, Jesper Winkler, Lindholt, Jes, Krarup, Nikolaj Thure, Borregaard, Britt, Uberg, Nikolai, Høgh, Annette

“…Bilateral blood pressure (BP) measurement is important in cardiovascular prevention for identifying systolic interarm BP difference (IAD) and hypertension. We…”
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Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial by Hansen, Christian Stevns, Lundby-Christiansen, Louise, Tarnow, Lise, Gluud, Christian, Hedetoft, Christoffer, Thorsteinsson, Birger, Hemmingsen, Bianca, Wiinberg, Niels, Sneppen, Simone B, Lund, Søren S, Krarup, Thure, Madsbad, Sten, Almdal, Thomas, Carstensen, Bendix, Jørgensen, Marit E

“…Metformin has been shown to have both neuroprotective and neurodegenerative effects. The aim of this study was to investigate the effect of metformin in…”
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Role of Gastrointestinal Hormones in Postprandial Reduction of Bone Resorption by Henriksen, Dennis B, Alexandersen, Peter, Bjarnason, Nina H, Vilsbøll, Tina, Hartmann, Bolette, Henriksen, Eva EG, Byrjalsen, Inger, Krarup, Thure, Holst, Jens J, Christiansen, Claus

“…Collagen type I fragments, reflecting bone resorption, and release of gut hormones were investigated after a meal. Investigations led to a dose escalation…”
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The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial by Samkani, Amirsalar, Skytte, Mads J, Anholm, Christian, Astrup, Arne, Deacon, Carolyn F, Holst, Jens J, Madsbad, Sten, Boston, Ray, Krarup, Thure, Haugaard, Steen B

“…Postprandial non-esterified fatty acid (NEFA) and triglyceride (TG) responses are increased in subjects with type 2 diabetes mellitus (T2DM) and may impair…”
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Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial by Thomsen, Mads N., Skytte, Mads J., Samkani, Amirsalar, Astrup, Arne, Fenger, Mogens, Frystyk, Jan, Hartmann, Bolette, Holst, Jens J., Larsen, Thomas M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens F., Haugaard, Steen B., Krarup, Thure

“…Background Carbohydrate restriction may benefit β-cell function and glucose metabolism in type 2 diabetes (T2D) but also leads to weight loss which in itself…”
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Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan by Olsen, Markus Harboe, Almdal, Thomas P., Madsbad, Sten, Ovesen, Christian, Gluud, Christian, Sneppen, Simone B., Breum, Leif, Hedetoft, Christoffer, Krarup, Thure, Lundby-Christensen, Louise, Mathiesen, Elisabeth R., Røder, Michael E., Vestergaard, Henrik, Wiinberg, Niels, Jakobsen, Janus C.

“…The evidence on the effects of metformin and insulin in type 2 diabetes patients on quality of life, patient satisfaction, and cardiovascular outcomes is…”
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Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots by Ingerslev, Lars R, Donkin, Ida, Fabre, Odile, Versteyhe, Soetkin, Mechta, Mie, Pattamaprapanont, Pattarawan, Mortensen, Brynjulf, Krarup, Nikolaj Thure, Barrès, Romain

“…Remodeling of the sperm epigenome by lifestyle factors before conception could account for altered metabolism in the next generation offspring. Here, we…”
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