Search Results - "KRALLI, A"

Estrogen-related Receptor Alpha (ERRα) is Required for PGC-1α-dependent Gene Expression in the Mouse Brain by McMeekin, L.J., Joyce, K.L., Jenkins, L.M., Bohannon, B.M., Patel, K.D., Bohannon, A.S., Patel, A., Fox, S.N., Simmons, M.S., Day, J.J., Kralli, A., Crossman, D.K., Cowell, R.M.

“…•ERR binding sites are enriched in the promoter region of PGC-1α-responsive genes.•ERRα antagonism impedes the ability of PGC-1α to upregulate genes in…”
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Corrigendum to “Estrogen-related Receptor Alpha (ERRα) is Required for PGC-1α-dependent Gene Expression in the Mouse Brain” [Neuroscience 479 (2021) 70–90] by McMeekin, L.J., Joyce, K.L., Jenkins, L.M., Bohannon, B.M., Patel, K.D., Bohannon, A.S., Patel, A., Fox, S.N., Simmons, M.S., Day, J.J., Kralli, A., Crossman, D.K., Cowell, R.M.

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Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy by Fox, S. N., McMeekin, L. J., Savage, C. H., Joyce, K. L., Boas, S. M., Simmons, M. S., Farmer, C. B., Ryan, J., Pereboeva, L., Becker, K., Auwerx, J., Sudarshan, S., Ma, J., Lee, A., Roberts, R. C., Crossman, D. K., Kralli, A., Cowell, R. M.

“…Many studies implicate mitochondrial dysfunction as a key contributor to cell loss in Parkinson disease (PD). Previous analyses of dopaminergic (DAergic)…”
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Regulation of the Transcriptional Coactivator PGC-1 via MAPK-Sensitive Interaction with a Repressor by Knutti, Darko, Kressler, Dieter, Kralli, Anastasia

“…Mechanisms and signals that regulate transcriptional coactivators are still largely unknown. Here we provide genetic evidence for a repressor that interacts…”
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PGC-1α regulates the isoform mRNA ratio of the alternatively spliced thyroid hormone receptor α transcript by Thijssen-Timmer, D C, Schiphorst, M Platvoet-Ter, Kwakkel, J, Emter, R, Kralli, A, Wiersinga, W M, Bakker, O

“…Transcripts derived from the thyroid hormone receptor α (TRα) gene are alternatively spliced resulting in a functional receptor TRα1 and a non-T3-binding…”
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LEM1, an ATP-Binding-Cassette Transporter, Selectively Modulates the Biological Potency of Steroid Hormones by Kralli, Anastasia, Bohen, Sean P., Yamamoto, Keith R.

“…The rat glucocorticoid receptor confers hormone-dependent transcriptional enhancement when expressed in yeast, thereby enabling the genetic identification of…”
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Direct Interaction Between Adenovirus E1A Protein and the TATA Box Binding Transcription Factor IID by Horikoshi, Nobuo, Maguire, Kathleen, Kralli, Anastasia, Maldonado, Edio, Reinberg, Danny, Weinmann, Roberto

“…Adenovirus E1A has long been known to activate/repress cellular and viral transcription. The transcriptional activity of nuclear extracts was depleted after…”
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A genetic analysis of glucocorticoid receptor signaling. Identification and characterization of ligand-effect modulators in Saccharomyces cerevisiae by Sitcheran, R, Emter, R, Kralli, A, Yamamoto, K R

“…To find novel components in the glucocorticoid signal transduction pathway, we performed a yeast genetic screen to identify ligand-effect modulators (LEMs),…”
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PGC-1, a versatile coactivator by Knutti, Darko, Kralli, Anastasia

“…PGC-1 was originally identified as a transcriptional coactivator of the nuclear receptor PPARγ. The expression pattern and induction by exposure to cold have…”
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The Estrogen-Related Receptor α (ERRα) Functions in PPARγ Coactivator 1α (PGC-1α)-Induced Mitochondrial Biogenesis by Schreiber, Sylvia N., Emter, Roger, Hock, M. Benjamin, Knutti, Darko, Cardenas, Jessica, Podvinec, Michael, Oakeley, Edward J., Kralli, Anastasia, Yamamoto, Keith R.

“…Estrogen-related receptor α (ERRα) is one of the first orphan nuclear receptors to be identified, yet its physiological functions are still unclear. We show…”
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Activation of nuclear receptor coactivator PGC-1α by arginine methylation by Teyssier, Catherine, Ma, Han, Emter, Roger, Kralli, Anastasia, Stallcup, Michael R.

“…Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a tissue-specific and inducible transcriptional coactivator for several nuclear…”
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The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha) by Schreiber, Sylvia N, Knutti, Darko, Brogli, Kathrin, Uhlmann, Thomas, Kralli, Anastasia

“…The estrogen-related receptor alpha (ERRalpha) is one of the first orphan nuclear receptors identified. Still, we know little about the mechanisms that…”
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Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise by Cartoni, Romain, Léger, Bertrand, Hock, M. Benjamin, Praz, Manu, Crettenand, Antoinette, Pich, Sara, Ziltener, Jean‐Luc, Luthi, François, Dériaz, Olivier, Zorzano, Antonio, Gobelet, Charles, Kralli, Anastasia, Russell, Aaron P.

“…Mitochondrial impairment is hypothesized to contribute to the pathogenesis of insulin resistance. Mitofusin (Mfn) proteins regulate the biogenesis and…”
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Negative regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells via a retinoic acid response element by KRALLI, A, GE, R, GRAEVEN, U, RICCIARDI, R. P, WEINMANN, R

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Endurance Training in Humans Leads to Fiber Type-Specific Increases in Levels of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 and Peroxisome Proliferator-Activated Receptor-α in Skeletal Muscle by RUSSELL, Aaron P, FEILCHENFELDT, Jonas, DERIAZ, Olivier, SCHREIBER, Sylvia, PRAZ, Manu, CRETTENAND, Antoinette, GOBELET, Charles, MEIER, Christoph A, BELL, David R, KRALLI, Anastasia, GIACOBINO, Jean-Paul

“…Endurance Training in Humans Leads to Fiber Type-Specific Increases in Levels of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 and Peroxisome…”
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A Tissue-Specific Coactivator of Steroid Receptors, Identified in a Functional Genetic Screen by Knutti, Darko, Kaul, Adesh, Kralli, Anastasia

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The PGC-1-related Protein PERC Is a Selective Coactivator of Estrogen Receptor α by Kressler, Dieter, Schreiber, Sylvia N., Knutti, Darko, Kralli, Anastasia

“…Peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1) is a tissue-specific coactivator that enhances the activity of many nuclear receptors and…”
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Down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding by GE, R, KRALLI, A, WEINMANN, R, RICCIARDI, R. P

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ERG6 and PDR5 regulate small lipophilic drug accumulation in yeast cells via distinct mechanisms by Emter, Roger, Heese-Peck, Antje, Kralli, Anastasia

“…Diagnosis and circumvention of multi-drug resistance requires an understanding of the underlying cellular mechanisms. In the model organism Saccharomyces…”
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Estrogen-related Receptor α Is a Repressor of Phosphoenolpyruvate Carboxykinase Gene Transcription by Herzog, Birger, Cardenas, Jessica, Hall, Robert K., Villena, Josep A., Budge, Philip J., Giguère, Vincent, Granner, Daryl K., Kralli, Anastasia

“…The orphan nuclear receptor estrogen-related receptor (ERR) α is a downstream effector of the transcriptional coactivator PGC-1α in the regulation of genes…”
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