Search Results - "KRÄNKEL, Nicolle"
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Concepts and Software Package for Efficient Quality Control in Targeted Metabolomics Studies: MeTaQuaC
Published in Analytical chemistry (Washington) (04-08-2020)“…Targeted quantitative mass spectrometry metabolite profiling is the workhorse of metabolomics research. Robust and reproducible data are essential for…”
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How to keep on going: Editorial comment on The long-term effects of a randomized trial comparing aerobic interval versus continuous training in coronary artery disease patients: one-year data from the SAINTEX-CAD study
Published in European journal of preventive cardiology (01-07-2016)Get full text
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Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors
Published in European journal of preventive cardiology (01-03-2020)“…Despite major efforts to reduce atherosclerotic cardiovascular disease (ASCVD) burden with conventional risk factor control, significant residual risk remains…”
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Human Adult Vena Saphena Contains Perivascular Progenitor Cells Endowed With Clonogenic and Proangiogenic Potential
Published in Circulation (New York, N.Y.) (20-04-2010)“…Clinical trials in ischemic patients showed the safety and benefit of autologous bone marrow progenitor cell transplantation. Non-bone marrow progenitor cells…”
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Abnormal High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2
Published in Immunity (Cambridge, Mass.) (18-04-2013)“…Endothelial injury and dysfunction (ED) represent a link between cardiovascular risk factors promoting hypertension and atherosclerosis, the leading cause of…”
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Micro–RNA-126 Reduces the Blood Thrombogenicity in Diabetes Mellitus via Targeting of Tissue Factor
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2016)“…OBJECTIVE—Diabetes mellitus involves vascular inflammatory processes and is a main contributor to cardiovascular mortality. Notably, heightened levels of…”
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Increased Expression of miR-483-3p Impairs the Vascular Response to Injury in Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-02-2019)“…Aggravated endothelial injury and impaired endothelial repair capacity contribute to the high cardiovascular risk in patients with type 2 diabetes (T2D), but…”
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Artificial sweetener sucralose: a possible modulator of autoimmune diseases
Published in Signal transduction and targeted therapy (02-10-2023)Get full text
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Galectin-3 as a Marker for Increased Thrombogenicity in COVID-19
Published in International journal of molecular sciences (22-04-2023)“…Galectin-3 is a beta-galactoside-binding lectin involved in inflammation and lung fibrosis and postulated to enhance thrombosis. In COVID-19, it is considered…”
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Disease Severity in Moderate-to-Severe COVID-19 Is Associated With Platelet Hyperreactivity and Innate Immune Activation
Published in Frontiers in immunology (11-03-2022)“…Hemostasis and inflammation are both dysregulated in patients with moderate-to-severe coronavirus disease 2019 (COVID-19). Yet, both processes can also be…”
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Novel insights into vascular repair mechanisms
Published in Current pharmaceutical design (2014)“…Endothelial cell injury is considered to play a critical role for development and progression of atherosclerosis as well as for complications after…”
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Structure-function relationships of HDL in diabetes and coronary heart disease
Published in JCI insight (16-01-2020)“…High-density lipoproteins (HDL) contain hundreds of lipid species and proteins and exert many potentially vasoprotective and antidiabetogenic activities on…”
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Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling
Published in Stem cells international (01-01-2018)“…Introduction. DPP4 inhibitors (gliptins) are commonly used antidiabetic drugs for the treatment of type 2 diabetes. Gliptins also act in a glucose-independent…”
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The Dynamic of Extracellular Vesicles in Patients With Subacute Stroke: Results of the “Biomarkers and Perfusion—Training-Induced Changes After Stroke” (BAPTISe) Study
Published in Frontiers in neurology (08-11-2021)“…Objective: Extracellular vesicles (EV) are sub-1 μm bilayer lipid coated particles and have been shown play a role in long-term cardiovascular outcome after…”
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Age Is Relative-Impact of Donor Age on Induced Pluripotent Stem Cell-Derived Cell Functionality
Published in Frontiers in cardiovascular medicine (25-01-2018)“…Induced pluripotent stem cells (iPSCs) avoid many of the restrictions that hamper the application of human embryonic stem cells: limited availability of source…”
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Rapid Inflammasome Activation Is Attenuated in Post-Myocardial Infarction Monocytes
Published in Frontiers in immunology (26-04-2022)“…Inflammasomes are crucial gatekeepers of the immune response, but their maladaptive activation associates with inflammatory pathologies. Besides canonical…”
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Physiologists as medical scientists: An early warning from the German academic system
Published in Physiological reports (01-11-2024)“…“Medical scientists” are postgraduate investigators who are engaged in biomedical research, and either hold a biomedical PhD or are qualified in medicine but…”
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The Role of NETosis and Complement Activation in COVID-19-Associated Coagulopathies
Published in Biomedicines (05-05-2023)“…Inflammation-induced coagulopathy is a common complication associated with coronavirus disease 2019 (COVID-19). We aim to evaluate the association of NETosis…”
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Early detection of myocardial infarction-microRNAs right at the time?
Published in Annals of translational medicine (01-12-2016)Get full text
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You can teach an old dog new tricks: angiopoietin‐1 instructs Tie2pos myeloid cells to promote neovascularization in ischemic limbs
Published in EMBO molecular medicine (01-06-2013)“…See related articles in EMBO Molecular Medicine http://dx.doi.org/10.1002/emmm.201302695 and http://dx.doi.org/10.1002/emmm.201302752…”
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