Search Results - "KOZOPAS, K. M"

MCL1, a Gene Expressed in Programmed Myeloid Cell Differentiation, has Sequence Similarity to BCL2 by Kozopas, Karen M., Yang, Tao, Buchan, Heather L., Zhou, Ping, Craig, Ruth W.

“…During their lifespan, immature cells normally pass through sequential transitions to a differentiated state and eventually undergo cell death. This…”
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Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions by ZHOU, P, QIAN, L, KOZOPAS, K. M, CRAIG, R. W

“…Mcl-1 is a member of the Bcl-2 family that was identified based on increased expression in myeloblastic leukemia cells undergoing differentiation. Mcl-1 was…”
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DWnt-2, a Drosophila Wnt gene required for the development of the male reproductive tract, specifies a sexually dimorphic cell fate by Kozopas, K M, Samos, C H, Nusse, R

“…The sexually dimorphic characteristics of the reproductive tract in Drosophila require that cells of the gonad and the genital disc be assigned sex-specific…”
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Human and mouse chromosomal mapping of the myeloid cell leukemia-1 gene: MCL1 maps to human chromosome 1q21, a region that is frequently altered in preneoplastic and neoplastic disease by Craig, R W, Jabs, E W, Zhou, P, Kozopas, K M, Hawkins, A L, Rochelle, J M, Seldin, M F, Griffin, C A

“…The MCL1 gene, recently identified in a myeloid leukemia cell line, has sequence similarity to BCL2, the gene at the t(14;18) translocation in follicular…”
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The Intracellular Distribution and Pattern of Expression of Mcl-1 Overlap with, but Are Not Identical to, Those of Bcl-2 by Yang, Tao, Kozopas, Karen M., Craig, Ruth W.

“…A family of genes related to the bcl-2 protooncogene has recently emerged. One member of this family, mcl-1, was cloned from a human myeloblastic leukemia cell…”
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Direct Flight Muscles in Drosophila Develop from Cells with Characteristics of Founders and Depend on DWnt-2 for Their Correct Patterning by Kozopas, Karen M., Nusse, Roel

“…The direct flight muscles (DFMs) of Drosophila allow for the fine control of wing position necessary for flight. In DWnt-2 mutant flies, certain DFMs are…”
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Improved coupling between proliferation-arrest and differentiation-induction in ML-1 human myeloblastic leukemia cells by Kozopas, K M, Buchan, H L, Craig, R W

“…Proliferation and differentiation are coupled in normal cells and are aberrant in leukemia cells. The studies reported here were aimed at more effectively…”
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