Search Results - "KOYNER, Jay L"

Pathophysiology of COVID-19-associated acute kidney injury by Legrand, Matthieu, Bell, Samira, Forni, Lui, Joannidis, Michael, Koyner, Jay L., Liu, Kathleen, Cantaluppi, Vincenzo

“…Although respiratory failure and hypoxaemia are the main manifestations of COVID-19, kidney involvement is also common. Available evidence supports a number of…”
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The Development of a Machine Learning Inpatient Acute Kidney Injury Prediction Model by Koyner, Jay L., Carey, Kyle A., Edelson, Dana P., Churpek, Matthew M.

“…OBJECTIVES:To develop an acute kidney injury risk prediction model using electronic health record data for longitudinal use in hospitalized patients…”
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Update on Perioperative Acute Kidney Injury by Zarbock, Alexander, Koyner, Jay L., Hoste, Eric A. J., Kellum, John A.

“…Acute kidney injury (AKI) in the perioperative period is a common complication and is associated with increased morbidity and mortality. A standard definition…”
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Clinical Use of the Urine Biomarker [TIMP-2] × [IGFBP7] for Acute Kidney Injury Risk Assessment by Vijayan, Anitha, MD, Faubel, Sarah, MD, Askenazi, David J., MD, MSPH, Cerda, Jorge, MD, Fissell, William H., MD, Heung, Michael, MD, Humphreys, Benjamin D., MD, PhD, Koyner, Jay L., MD, Liu, Kathleen D., MD, PhD, Mour, Girish, MBBS, MD, Nolin, Thomas D., PharmD, PhD, Bihorac, Azra, MD

“…Acute kidney injury (AKI) is a serious complication, commonly occurring in the critically ill population, with devastating short- and long-term consequences…”
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Clinical Utility of Biomarkers of AKI in Cardiac Surgery and Critical Illness by Koyner, Jay L, Parikh, Chirag R

“…AKI is a common and serious complication that is associated with several adverse outcomes in hospitalized patients. The past several years have seen a large…”
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Development of a Multicenter Ward-Based AKI Prediction Model by Koyner, Jay L, Adhikari, Richa, Edelson, Dana P, Churpek, Matthew M

“…Identification of patients at risk for AKI on the general wards before increases in serum creatinine would enable preemptive evaluation and intervention to…”
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CSA-AKI: Incidence, Epidemiology, Clinical Outcomes, and Economic Impact by Schurle, Alan, Koyner, Jay L

“…Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication following cardiac surgery and reflects a complex biological combination of…”
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Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity by Koyner, Jay L, Davison, Danielle L, Brasha-Mitchell, Ermira, Chalikonda, Divya M, Arthur, John M, Shaw, Andrew D, Tumlin, James A, Trevino, Sharon A, Bennett, Michael R, Kimmel, Paul L, Seneff, Michael G, Chawla, Lakhmir S

“…Clinicians have access to limited tools that predict which patients with early AKI will progress to more severe stages. In early AKI, urine output after a…”
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Biomarkers Predict Progression of Acute Kidney Injury after Cardiac Surgery by KOYNER, Jay L, GARG, Amit X, COCA, Steven G, SINT, Kyaw, THIESSEN-PHILBROOK, Heather, PATEL, Uptal D, SHLIPAK, Michael G, PARIKH, Chirag R

“…Being able to predict whether AKI will progress could improve monitoring and care, guide patient counseling, and assist with enrollment into trials of AKI…”
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Postoperative Biomarkers Predict Acute Kidney Injury and Poor Outcomes after Adult Cardiac Surgery by PARIKH, Chirag R, COCA, Steven G, KRAWCZESKI, Catherine D, PASSIK, Cary S, SWAMINATHAN, Madhav, GARG, Amit X, THIESSEN-PHILBROOK, Heather, SHLIPAK, Michael G, KOYNER, Jay L, ZHU WANG, EDELSTEIN, Charles L, DEVARAJAN, Prasad, PATEL, Uptal D, ZAPPITELLI, Michael

“…Acute kidney injury (AKI) is a frequent complication of cardiac surgery and increases morbidity and mortality. The identification of reliable biomarkers that…”
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Postoperative Biomarkers Predict Acute Kidney Injury and Poor Outcomes after Pediatric Cardiac Surgery by PARIKH, Chirag R, DEVARAJAN, Prasad, SHLIPAK, Michael G, GARG, Amit X, KRAWCZESKI, Catherine D, ZAPPITELLI, Michael, SINT, Kyaw, THIESSEN-PHILBROOK, Heather, SIMON LI, KIM, Richard W, KOYNER, Jay L, COCA, Steven G, EDELSTEIN, Charles L

“…Acute kidney injury (AKI) occurs commonly after pediatric cardiac surgery and associates with poor outcomes. Biomarkers may help the prediction or early…”
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Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication by BIHORAC, Azra, CHAWLA, Lakhmir S, HEUNG, Michael, JORTANI, Saeed, KLEERUP, Eric, KOYNER, Jay L, KRELL, Kenneth, LETOURNEAU, Jennifer, LISSAUER, Matthew, MINER, James, NGUYEN, H. Bryant, ORTEGA, Luis M, SHAW, Andrew D, SELF, Wesley H, SELLMAN, Richard, JING SHI, STRASESKI, Joely, SZALADOS, James E, WILBER, Scott T, WALKER, Michael G, WILSON, Jason, WUNDERINK, Richard, ZIMMERMAN, Janice, AL-KHAFAJI, Ali, KELLUM, John A, DAVISON, Danielle L, DEMUTH, George E, FITZGERALD, Robert, NG GONG, Michelle, GRAHAM, Derrel D, GUNNERSON, Kyle

“…We recently reported two novel biomarkers for acute kidney injury (AKI), tissue inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding…”
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Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group by Nadim, Mitra K., Forni, Lui G., Bihorac, Azra, Hobson, Charles, Koyner, Jay L., Shaw, Andrew, Arnaoutakis, George J., Ding, Xiaoqiang, Engelman, Daniel T., Gasparovic, Hrvoje, Gasparovic, Vladimir, Herzog, Charles A., Kashani, Kianoush, Katz, Nevin, Liu, Kathleen D., Mehta, Ravindra L., Ostermann, Marlies, Pannu, Neesh, Pickkers, Peter, Price, Susanna, Ricci, Zaccaria, Rich, Jeffrey B., Sajja, Lokeswara R., Weaver, Fred A., Zarbock, Alexander, Ronco, Claudio, Kellum, John A.

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Development and standardization of a furosemide stress test to predict the severity of acute kidney injury by Chawla, Lakhmir S, Davison, Danielle L, Brasha-Mitchell, Ermira, Koyner, Jay L, Arthur, John M, Shaw, Andrew D, Tumlin, James A, Trevino, Sharon A, Kimmel, Paul L, Seneff, Michael G

“…In the setting of early acute kidney injury (AKI), no test has been shown to definitively predict the progression to more severe stages. We investigated the…”
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Urinary Biomarkers in the Clinical Prognosis and Early Detection of Acute Kidney Injury by Koyner, Jay L, Vaidya, Vishal S, Bennett, Michael R, Ma, Qing, Worcester, Elaine, Akhter, Shahab A, Raman, Jai, Jeevanandam, Valluvan, O'Connor, Micheal F, Devarajan, Prasad, Bonventre, Joseph V, Murray, Patrick T

“…Several novel urinary biomarkers have shown promise in the early detection and diagnostic evaluation of acute kidney injury (AKI). Clinicians have limited…”
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Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel by Guzzi, Louis M, Bergler, Tobias, Binnall, Brian, Engelman, Daniel T, Forni, Lui, Germain, Michael J, Gluck, Eric, Göcze, Ivan, Joannidis, Michael, Koyner, Jay L, Reddy, V Seenu, Rimmelé, Thomas, Ronco, Claudio, Textoris, Julien, Zarbock, Alexander, Kellum, John A

“…The first FDA-approved test to assess risk for acute kidney injury (AKI), [TIMP-2]•[IGFBP7], is clinically available in many parts of the world, including the…”
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Human miRNome profiling identifies microRNAs differentially present in the urine after kidney injury by Ramachandran, Krithika, Saikumar, Janani, Bijol, Vanesa, Koyner, Jay L, Qian, Jing, Betensky, Rebecca A, Waikar, Sushrut S, Vaidya, Vishal S

“…Extracellular microRNAs (miRNAs) have been proposed as potentially robust and stable biomarkers of various disease conditions. The primary objective of this…”
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Performance of Kidney Injury Molecule-1 and Liver Fatty Acid-Binding Protein and Combined Biomarkers of AKI after Cardiac Surgery by Parikh, Chirag R, Thiessen-Philbrook, Heather, Garg, Amit X, Kadiyala, Deepak, Shlipak, Michael G, Koyner, Jay L, Edelstein, Charles L, Devarajan, Prasad, Patel, Uptal D, Zappitelli, Michael, Krawczeski, Catherine D, Passik, Cary S, Coca, Steven G

“…AKI is common and novel biomarkers may help provide earlier diagnosis and prognosis of AKI in the postoperative period. This was a prospective, multicenter…”
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Urinary Biomarkers of AKI and Mortality 3 Years after Cardiac Surgery by COCA, Steven G, GARG, Amit X, THIESSEN-PHILBROOK, Heather, KOYNER, Jay L, PATEL, Uptal D, KRUMHOLZ, Harlan M, SHLIPAK, Michael G, PARIKH, Chirag R

“…Urinary biomarkers of AKI provide prognostic value for in-hospital outcomes, but little is known about their association with longer-term mortality after…”
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Internal and External Validation of a Machine Learning Risk Score for Acute Kidney Injury by Churpek, Matthew M, Carey, Kyle A, Edelson, Dana P, Singh, Tripti, Astor, Brad C, Gilbert, Emily R, Winslow, Christopher, Shah, Nirav, Afshar, Majid, Koyner, Jay L

“…Acute kidney injury (AKI) is associated with increased morbidity and mortality in hospitalized patients. Current methods to identify patients at high risk of…”
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