Search Results - "KOWARSCH, Andreas"

MicroRNA loss enhances learning and memory in mice by Konopka, Witold, Kiryk, Anna, Novak, Martin, Herwerth, Marina, Parkitna, Jan Rodriguez, Wawrzyniak, Marcin, Kowarsch, Andreas, Michaluk, Piotr, Dzwonek, Joanna, Arnsperger, Tabea, Wilczynski, Grzegorz, Merkenschlager, Matthias, Theis, Fabian J, Köhr, Georg, Kaczmarek, Leszek, Schütz, Günther

“…Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role in a modulation of translation of mRNA transcripts necessary for…”
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PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes by Ruepp, Andreas, Kowarsch, Andreas, Schmidl, Daniel, Buggenthin, Felix, Brauner, Barbara, Dunger, Irmtraud, Fobo, Gisela, Frishman, Goar, Montrone, Corinna, Theis, Fabian J

“…In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database…”
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Correlated mutations: a hallmark of phenotypic amino acid substitutions by Kowarsch, Andreas, Fuchs, Angelika, Frishman, Dmitrij, Pagel, Philipp

“…Point mutations resulting in the substitution of a single amino acid can cause severe functional consequences, but can also be completely harmless…”
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High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms by Jeromin, Sabine, Haferlach, Torsten, Grossmann, Vera, Alpermann, Tamara, Kowarsch, Andreas, Haferlach, Claudia, Kern, Wolfgang, Schnittger, Susanne

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Screening for NPHS2 Mutations May Help Predict FSGS Recurrence after Transplantation by JUNGRAITHMAYR, Therese C, HOFER, Katrin, PAGEL, Philipp, PFEIFFER, Karl P, SCHÄFER, Franz, SCHÖNERMARCK, Ulf, SEEMAN, Tomas, TOENSHOFF, Burkhard, WEBER, Stefanie, WINS, Michelle P, ZSCHOCKE, Johannes, ZIMMERHACKL, Lothar B, COCHAT, Pierre, CHERNIN, Gil, CORTINA, Gerard, FARGUE, Sonja, GRIMM, Paul, KNUEPPEL, Tanja, KOWARSCH, Andreas, NEUHAUS, Thomas

“…Steroid-resistant focal segmental glomerulosclerosis (FSGS) often recurs after renal transplantation. In this international survey, we sought to identify…”
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Tissue-specific target analysis of disease-associated microRNAs in human signaling pathways by Kowarsch, Andreas, Marr, Carsten, Schmidl, Daniel, Ruepp, Andreas, Theis, Fabian J

“…MicroRNAs are a large class of post-transcriptional regulators that bind to the 3' untranslated region of messenger RNAs. They play a critical role in many…”
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Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases by SCHNITTGER, Susanne, BACHER, Ulrike, KERN, Wolfgang, HAFERLACH, Claudia, HAFERLACH, Torsten, ALPERMANN, Tamara, REITER, Andreas, ULKE, Madlen, DICKER, Frank, EDER, Christiane, KOHLMANN, Alexander, GROSSMANN, Vera, KOWARSCH, Andreas

“…We analyzed 636 patients with diverse myeloproliferative neoplasms or myelodysplastic/myeloproliferative neoplasms for mutations of the Casitas B-cell lymphoma…”
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Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation by Kowarsch, Andreas, Blöchl, Florian, Bohl, Sebastian, Saile, Maria, Gretz, Norbert, Klingmüller, Ursula, Theis, Fabian J

“…External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of…”
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miTALOS: analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs by Kowarsch, Andreas, Preusse, Martin, Marr, Carsten, Theis, Fabian J

“…MicroRNAs (miRNAs) are an important class of post-transcriptional regulators of gene expression that are involved in various cellular and phenotypic processes…”
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Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity by Bacher, Ulrike, Schnittger, Susanne, Macijewski, Katja, Grossmann, Vera, Kohlmann, Alexander, Alpermann, Tamara, Kowarsch, Andreas, Nadarajah, Niroshan, Kern, Wolfgang, Haferlach, Claudia, Haferlach, Torsten

“…In 2008, the World Health Organization introduced CEBPA (encoding the CCAAT/enhancer binding protein)–mutated acute myeloid leukemia (AML) as a provisional…”
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Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets by RAIA, Valentina, SCHILLING, Marcel, GRETZ, Norbert, TIMMER, Jens, THEIS, Fabian, LEHMANN, Wolf-Dieter, LICHTER, Peter, KLINGMÜLLER, Ursula, BÖHM, Martin, HAHN, Bettina, KOWARSCH, Andreas, RAUE, Andreas, STICHT, Carsten, BOHL, Sebastian, SAILE, Maria, MÖLLER, Peter

“…Primary mediastinal B-cell lymphoma (PMBL) and classical Hodgkin lymphoma (cHL) share a frequent constitutive activation of JAK (Janus kinase)/STAT signaling…”
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PhenomiR: microRNAs in human diseases and biological processes by Ruepp, Andreas, Kowarsch, Andreas, Theis, Fabian

“…The association of dysregulated microRNAs (miRNAs) and diseases has been shown in a variety of studies. Here, we review a resource denoted as PhenomiR,…”
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Classification of HER2/neu Status in Gastric Cancer Using a Breast-Cancer Derived Proteome Classifier by Balluff, Benjamin, Elsner, Mareike, Kowarsch, Andreas, Rauser, Sandra, Meding, Stephan, Schuhmacher, Christoph, Feith, Marcus, Herrmann, Ken, Röcken, Christoph, Schmid, Roland M., Höfler, Heinz, Walch, Axel, Ebert, Matthias P.

“…HER2-testing in breast and gastric cancers is mandatory for the treatment with trastuzumab. We hypothesized that imaging mass spectrometry (IMS) of breast…”
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miTALOS: Analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs by Kowarsch, Andreas, Preusse, Martin, Marr, Carsten, Theis, Fabian J.

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MicroRNAs coordinately regulate protein complexes by Sass, Steffen, Dietmann, Sabine, Burk, Ulrike C, Brabletz, Simone, Lutter, Dominik, Kowarsch, Andreas, Mayer, Klaus F, Brabletz, Thomas, Ruepp, Andreas, Theis, Fabian J, Wang, Yu

“…In animals, microRNAs (miRNAs) regulate the protein synthesis of their target messenger RNAs (mRNAs) by either translational repression or deadenylation…”
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Correlated Mutations: A Hallmark of Phenotypic Amino Acid Substitutions: e1000923 by Kowarsch, Andreas, Fuchs, Angelika, Frishman, Dmitrij, Pagel, Philipp

“…Point mutations resulting in the substitution of a single amino acid can cause severe functional consequences, but can also be completely harmless…”
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Extrinsically regulated Gadd45γ balances hematopoietic stem cell self-renewal and differentiation by Thalheimer, Frederic, Wingert, Susanne, De Giacomo, Pangrzio, Kowarsch, Andreas, Theis, Fabian, Hennighausen, Lothar, Schroeder, Timm, Rieger, Michael

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The cytokine-induced microrna193b modulates ckit expression and STAT5 signaling by Haetscher, Nadine, Feuermann, Yonatan, Wingert, Susanne, Thalheimer, Frederic, Weiser, Christian, Kowarsch, Andreas, Theis, Fabian, Schroeder, Timm, Rieger, Michael, Hennighausen, Lothar

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