Search Results - "KOVATICH, A. J"

MLH1 Promoter Methylation and Gene Silencing is the Primary Cause of Microsatellite Instability in Sporadic Endometrial Cancers by Simpkins, Sally B., Bocker, Tina, Swisher, Elizabeth M., Mutch, David G., Gersell, Deborah J., Kovatich, Albert J., Palazzo, Juan P., Fishel, Richard, Goodfellow, Paul J.

“…Defective DNA mismatch repair in human tumors leads to genome-wide instability of microsatellite repeats and a molecular phenotype referred to as…”
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Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery : Clinicopathologic and immunohistochemical study of 26 cases by MIETTINEN, M, MONIHAN, J. M, SARLOMO-RIKALA, M, KOVATICH, A. J, CARR, N. J, EMORY, T. S, SOBIN, L. H

“…Gastrointestinal stromal tumor or smooth muscle tumor (GIST) is the designation for a major subset of gastrointestinal mesenchymal tumors that histologically,…”
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Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism by Goodman, C R, Sato, T, Peck, A R, Girondo, M A, Yang, N, Liu, C, Yanac, A F, Kovatich, A J, Hooke, J A, Shriver, C D, Mitchell, E P, Hyslop, T, Rui, H

“…Therapy resistance remains a major problem in estrogen receptor-α (ERα)-positive breast cancer. A subgroup of ERα-positive breast cancer is characterized by…”
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Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression by Sato, T, Tran, T H, Peck, A R, Girondo, M A, Liu, C, Goodman, C R, Neilson, L M, Freydin, B, Chervoneva, I, Hyslop, T, Kovatich, A J, Hooke, J A, Shriver, C D, Fuchs, S Y, Rui, H

“…Prolactin controls the development and function of milk-producing breast epithelia but also supports growth and differentiation of breast cancer, especially…”
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hMSH5 : A human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis by BOCKER, T, BARUSEVICIUS, A, KOVATICH, A. J, FISHEL, R, SNOWDEN, T, RASIO, D, GUERRETTE, S, ROBBINS, D, SCHMIDT, C, BURCZAK, J, CROCE, C. M, COPELAND, T

“…MutS homologues have been identified in nearly all organisms examined to date. They play essential roles in maintaining mitotic genetic fidelity and meiotic…”
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Extramammary Paget disease is characterized by the consistent lack of estrogen and progesterone receptors but frequently expresses androgen receptor by DIAZ DE LEON, E, CARCANGIU, M. L, GATALICA, Z, PRIETO, V. G, MCCUE, P. A, BURCHETTE, J. L, TO, G, NORRIS, B. A, KOVATICH, A. J, SANCHEZ, R. L, KRIGMAN, H. R

“…Extramammary Paget disease (EPD) is an uncommon cutaneous malignant neoplasm that arises in areas rich in apocrine glands (perineum, vulva, and axilla)…”
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Loss of FHIT Expression in Transitional Cell Carcinoma of the Urinary Bladder by Baffa, Raffaele, Gomella, Leonard G., Vecchione, Andrea, Bassi, Pierfrancesco, Mimori, Koshi, Sedor, John, Calviello, Coleen M., Gardiman, Marina, Minimo, Corrado, Strup, Stephen E., McCue, Peter A., Kovatich, Albert J., Pagano, Francesco, Huebner, Kay, Croce, Carlo M.

“…Cytogenetic and loss of heterozygosity (LOH) studies demonstrated chromosome 3p deletions in transitional cell carcinoma (TCC). We recently cloned the tumor…”
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Keratin subsets in papillary and follicular thyroid lesions : A paraffin section analysis with diagnostic implications by MIETTINEN, M, KOVATICH, A. J, KÄRKKÄINEN, P

“…Previous studies indicate that keratins 7, 8 and 18 are present in all thyroid papillary and follicular lesions, but the distribution of other keratins has…”
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CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34 by Sarlomo-Rikala, M, Kovatich, A J, Barusevicius, A, Miettinen, M

“…Gastrointestinal stromal tumors (GISTs) represent a distinct and the most important subset of mesenchymal tumors of the GI tract. These tumors are both…”
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Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas by INGVARSSON, S, AGNARSSON, B. A, MCCUE, P. A, SIGBJORNSDOTTIR, B. I, KONONEN, J, KALLIONIEMI, O.-P, BARKARDOTTIR, R. B, KOVATICH, A. J, SCHWARTING, R, HAUCK, W. W, HUEBNER, K

“…Evidence for alteration of the FHIT gene in a significant fraction of breast carcinomas has been reported, in apparent concordance with loss of heterozygosity…”
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Cell-type- and tumour-type-related patterns of bcl-2 reactivity in mesenchymal cells and soft tissue tumours by MIETTINEN, M, SARLOMO-RIKALA, M, KOVATICH, A. J

“…Bcl-2 is one of the many proteins that regulate programmed cell death and is overexpressed in B-cell lymphomas. The expression of bcl-2 in mesenchymal cells…”
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Immunocytochemical evaluation of HBME-1, CA 19-9, and CD-15 (Leu-M1) in fine-needle aspirates of thyroid nodules by van Hoeven, K. H., Kovatich, Albert J., Miettinen, Markku

“…Overlapping morphologic patterns that may be observed in goiter, follicular adenoma, and papillary carcinoma can limit the cytologic evaluation of the thyroid…”
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Quantitative image analysis of MIB-1 reactivity in inflammatory, hyperplastic, and neoplastic endocervical lesions by van Hoeven, K H, Ramondetta, L, Kovatich, A J, Bibbo, M, Dunton, C J

“…The diagnosis of endocervical neoplasia can be difficult as it is sometimes mimicked by proliferative or reactive glands. MIB-1 is a proliferation marker that…”
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Ki-67 Antigen Staining as an Adjunct to Identifying Cervical Intraepithelial Neoplasia by Dunton, Charles J., van Hoeven, Karen H., Kovatich, Al J., Oliver, Robin E., Scacheri, Robert Q., Cater, Jacqueline R., Carlson, John A.

“…The purpose of the work was to determine the feasibility and predictive value of Ki-67 immunostaining of cervical cytology and the detection of cervical…”
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Lupus profundus, indeterminate lymphocytic lobular panniculitis and subcutaneous T-cell lymphoma: a spectrum of subcuticular T-cell lymphoid dyscrasia by Magro, Cynthia M., Crowson, A. Neil, Kovatich, Al J., Burns, Frank

“…Introduction: The diagnosis and classification of lymphocytic lobular panniculitis (LLP) has historically proven to be a difficult challenge. We encountered 32…”
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Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma by Mastrangelo, M J, Maguire, Jr, H C, Eisenlohr, L C, Laughlin, C E, Monken, C E, McCue, P A, Kovatich, A J, Lattime, E C

“…Seven immunocompetent, revaccinated patients with surgically incurable cutaneous melanoma underwent treatment of dermal and/or subcutaneous metastases with…”
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Immunohistochemical staining for proliferating cell nuclear antigen, BCL2, and Ki-67 in vulvar tissues by van Hoeven, K H, Kovatich, A J

“…Dysplastic cells of the uterine cervix commonly react with antibodies to Ki-67 and proliferating cell nuclear antigen (PCNA), but less is known regarding the…”
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Calponin and h-caldesmon in soft tissue tumors: consistent h-caldesmon immunoreactivity in gastrointestinal stromal tumors indicates traits of smooth muscle differentiation by Miettinen, M M, Sarlomo-Rikala, M, Kovatich, A J, Lasota, J

“…Currently, the immunohistochemical evaluation of smooth muscle differentiation is usually based on desmin, which also reacts with skeletal muscle and is not…”
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p53 Immunohistochemistry for Distinguishing Reactive Mesothelium from Low Grade Ovarian Carcinoma by Pindzola, Ander, Kovatich, Albert J., Bibbo, Marluce

“…To determine the utility of immunohistochemical staining for p53 in cell block material for distinguishing reactive mesothelium from borderline or low grade…”
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Fhit expression in gastric adenocarcinoma : Correlation with disease stage and survival by CAPUZZI, D, SANTORO, E, HAUCK, W. W, KOVATICH, A. J, ROSATO, F. E, BAFFA, R, HUEBNER, K, MCCUE, P. A

“…The FHIT gene is inactivated by deletion in a large fraction of human tumors, including gastric carcinomas, and the Fhit protein has been proposed to act as a…”
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