Search Results - "KOVALOVICH, Kellen"

Interleukin-6 Protects against Fas-mediated Death by Establishing a Critical Level of Anti-apoptotic Hepatic Proteins FLIP, Bcl-2, and Bcl-xL by Kovalovich, Kellen, Li, Wei, DeAngelis, Robert, Greenbaum, Linda E., Ciliberto, Gennaro, Taub, Rebecca

“…Previous studies showed that following acute carbon tetrachloride (CCl4) treatment, interleukin-6 null (IL-6−/−) mice develop increased hepatocellular injury,…”
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Increased toxin‐induced liver injury and fibrosis in interleukin‐6–deficient mice by Kovalovich, Kellen, DeAngelis, Robert A., Li, Wei, Furth, Emma E., Ciliberto, Gennaro, Taub, Rebecca

“…Interleukin‐6 null (IL‐6−/−) mice have impaired liver regeneration and increased liver necrosis following partial hepatectomy that is corrected with IL‐6…”
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Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression by BANSAL, Meena B, KOVALOVICH, Kellen, TAUB, Rebecca A, GUPTA, Ritu, WEI LI, AGARWAL, Akansha, RADBILL, Brian, ALVAREZ, Carlos E, SAFADI, Rifaat, FIEL, M. Isabel, FRIEDMAN, Scott L

“…Interleukin-6 stimulates liver regeneration and promotes hepatoprotection following experimental liver injury, but underlying mechanisms have not been fully…”
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Interleukin-6 from intrahepatic cells of bone marrow origin is required for normal murine liver regeneration by Aldeguer, Xavier, Debonera, Fotini, Shaked, Abraham, Krasinkas, Alyssa M., Gelman, Andrew E., Que, Xingyi, Zamir, Gideon A., Hiroyasu, Shungo, Kovalovich, Kellen K., Taub, Rebecca, Olthoff, Kim M.

“…Interleukin-6 (IL-6) is required for normal liver regeneration, but the specific cellular source of this growth factor is unknown. We investigated whether this…”
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Fas-induced apoptosis in mouse hepatocytes is dependent on C/EBPβ by Mukherjee, Debjani, Kaestner, Klaus H., Kovalovich, Kellen K., Greenbaum, Linda E.

“…Apoptotic cell death in the liver in response to activation of the Fas pathway has been implicated in human disease states as well as liver remodeling and…”
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Global changes in interleukin-6–dependent gene expression patterns in mouse livers after partial hepatectomy by Li, Wei, Liang, Xianping, Leu, Julie I., Kovalovich, Kellen, Ciliberto, Gennaro, Taub, Rebecca

“…Liver regeneration following 70% partial hepatectomy leads to rapid activation of genes in the remnant liver. Interleukin-6 deficient (IL-6 −/−) mice have…”
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Normal liver regeneration in p50/nuclear factor κB1 knockout mice by DeAngelis, Robert A., Kovalovich, Kellen, Cressman, Drew E., Taub, Rebecca

“…Nuclear factor κB (NF-κB) is rapidly activated during liver regeneration following partial hepatectomy or carbon tetrachloride (CCl4)-mediated liver injury and…”
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Interleukin-6 protects hepatocytes from CCl 4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression by Bansal, Meena B., Kovalovich, Kellen, Gupta, Ritu, Li, Wei, Agarwal, Akansha, Radbill, Brian, Alvarez, Carlos E., Safadi, Rifaat, Fiel, M. Isabel, Friedman, Scott L., Taub, Rebecca A.

“…Interleukin-6 stimulates liver regeneration and promotes hepatoprotection following experimental liver injury, but underlying mechanisms have not been fully…”
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CCAAT enhancer binding protein B is required for Fas-induced apoptosis in liver by Greenbaum, Linda Ellen, Kovalovich, Kellen, Taub, Rebecca, Ciliberto, Gennaro, Poli, Valeria

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Liver‐specific and proliferation‐induced deoxyribonuclease I hypersensitive sites in the mouse insulin‐like growth factor binding protein‐1 gene by Crissey, Mary Ann, Leu, Julia I., De Angelis, Robert A., Greenbaum, Linda E., Scearce, L. Marie, Kovalovich, Kellen, Taub, Rebecca

“…The insulin‐like growth factor binding protein‐1 (IGFBP‐1) gene is highly expressed in fetal, perinatal, and regenerating liver. Up‐regulation is…”
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OUTCOME OF TRANSPLANTATION OF MARGINAL LIVER GRAFTS IN HIGH-NEED PATIENTS: EVALUATION OF PHYSICIAN BASED ORGAN ALLOCATION: Abstract# 988 by Markmann, James F., Velidedeoglu, Ergun, Olthoff, Kim M., Shaked, Avi, Zamir, Gideon, Stewart, Charmaine, Zeldin, Gillian, Nunes, Frederick A., Schultz, Christopher F., Anne, Burke F., Hibbler, Jane, Kovalovich, Kellen, Abrams, John, Lucey, Mike R.

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