Search Results - "KOUTSOPOULOS, Anastasios"

Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts by Kerdidani, Dimitra, Aerakis, Emmanouil, Verrou, Kleio-Maria, Angelidis, Ilias, Douka, Katerina, Maniou, Maria-Anna, Stamoulis, Petros, Goudevenou, Katerina, Prados, Alejandro, Tzaferis, Christos, Ntafis, Vasileios, Vamvakaris, Ioannis, Kaniaris, Evangelos, Vachlas, Konstantinos, Sepsas, Evangelos, Koutsopoulos, Anastasios, Potaris, Konstantinos, Tsoumakidou, Maria

“…A key unknown of the functional space in tumor immunity is whether CD4 T cells depend on intratumoral MHCII cancer antigen recognition. MHCII-expressing,…”
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Clinical Relevance of Immune Checkpoints on Circulating Tumor Cells in Breast Cancer by Papadaki, Maria A, Koutsopoulos, Anastasios V, Tsoulfas, Panormitis G, Lagoudaki, Eleni, Aggouraki, Despoina, Monastirioti, Alexia, Koutoulaki, Chara, Apostolopoulou, Christina A, Merodoulaki, Aikaterini C, Papadaki, Chara, Mavroudis, Dimitrios, Agelaki, Sofia

“…The role of CD47 and PD-L1 expression on circulating tumor cells (CTCs) remains unclear, and it is currently unknown whether their distribution varies between…”
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PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study by Tzanikou, Eleni, Markou, Athina, Politaki, Eleni, Koutsopoulos, Anastasios, Psyrri, Amanda, Mavroudis, Dimitris, Georgoulias, Vassilis, Lianidou, Evi

“…Liquid biopsy analysis, mainly based on circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), provides an extremely powerful tool for the molecular…”
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Upregulation of citrullination pathway: From Autoimmune to Idiopathic Lung Fibrosis by Samara, Katerina D, Trachalaki, Athina, Tsitoura, Eliza, Koutsopoulos, Anastasios V, Lagoudaki, Eleni D, Lasithiotaki, Ismini, Margaritopoulos, George, Pantelidis, Panagiotis, Bibaki, Eleni, Siafakas, Nikolaos M, Tzanakis, Nikolaos, Wells, Athol U, Antoniou, Katerina M

“…Increased protein citrullination and peptidylarginine deiminases (PADIs), which catalyze the citrullination process, are central in Rheumatoid arthritis…”
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Evaluation of PD-L1/PD-1 on circulating tumor cells in patients with advanced non-small cell lung cancer by Kallergi, Galatea, Vetsika, Eleni-Kyriaki, Aggouraki, Despoina, Lagoudaki, Eleni, Koutsopoulos, Anastasios, Koinis, Filippos, Katsarlinos, Panagiotis, Trypaki, Maria, Messaritakis, Ippokratis, Stournaras, Christos, Georgoulias, Vassilis, Kotsakis, Athanasios

“…Background: Circulating tumor cells (CTCs) could escape from the immune system through the programmed death-ligand 1 (PD-L1)/programmed cell death protein 1…”
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The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization by Kallergi, Galatea, Tsintari, Vasileia, Sfakianakis, Stelios, Bei, Ekaterini, Lagoudaki, Eleni, Koutsopoulos, Anastasios, Zacharopoulou, Nefeli, Alkahtani, Saad, Alarifi, Saud, Stournaras, Christos, Zervakis, Michalis, Georgoulias, Vassilis

“…Circulating tumor cells (CTCs) are important for metastatic dissemination of cancer. They can provide useful information, regarding biological features and…”
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Phenotypic characterization of circulating tumor cells in the peripheral blood of patients with small cell lung cancer by Messaritakis, Ippokratis, Politaki, Eleni, Kotsakis, Athanasios, Dermitzaki, Eleftheria-Kleio, Koinis, Filippos, Lagoudaki, Eleni, Koutsopoulos, Anastasios, Kallergi, Galatea, Souglakos, John, Georgoulias, Vassilis

“…To evaluate the phenotypic heterogeneity of circulating tumor cells (CTCs) based on the expression of proliferative, apoptotic and Epithelial-to-Mesenchymal…”
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The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer by Giatromanolaki, Alexandra, Koukourakis, Michael I., Koutsopoulos, Anastasios, Mendrinos, Savvas, Sivridis, Efthimios

“…Tumor-associated stroma (TAS) is not simply a supporting element for cancer cells, but plays an important role in tumor growth, invasion and metastasis…”
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Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients by Siganaki, Marianna, Koutsopoulos, Anastasios V, Neofytou, Eirini, Vlachaki, Eleni, Psarrou, Maria, Soulitzis, Nikolaos, Pentilas, Nikolaos, Schiza, Sophia, Siafakas, Nikolaos M, Tzortzaki, Eleni G

“…Abnormal apoptotic events in chronic obstructive pulmonary disease (COPD) subvert cellular homeostasis and may play a primary role in its pathogenesis…”
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LKB1 Loss Correlates with STING Loss and, in Cooperation with β-Catenin Membranous Loss, Indicates Poor Prognosis in Patients with Operable Non-Small Cell Lung Cancer by Lagoudaki, Eleni D, Koutsopoulos, Anastasios V, Sfakianaki, Maria, Papadaki, Chara, Manikis, Georgios C, Voutsina, Alexandra, Trypaki, Maria, Tsakalaki, Eleftheria, Fiolitaki, Georgia, Hatzidaki, Dora, Yiachnakis, Emmanuel, Koumaki, Dimitra, Mavroudis, Dimitrios, Tzardi, Maria, Stathopoulos, Efstathios N, Marias, Kostas, Georgoulias, Vassilis, Souglakos, John

“…To investigate the incidence and prognostically significant correlations and cooperations of LKB1 loss of expression in non-small cell lung cancer (NSCLC),…”
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CD8+ PD-1+ T-cells and PD-L1+ circulating tumor cells in chemotherapy-naïve non-small cell lung cancer: towards their clinical relevance? by Kotsakis, Athanasios, Kallergi, Galatea, Aggouraki, Despoina, Lyristi, Zaharoula, Koinis, Filippos, Lagoudaki, Eleni, Koutsopoulos, Anastasios, Georgoulias, Vassilis, Vetsika, Eleni-Kyriaki

“…Background: Since tumor cells may escape from immune surveillance through the programmed cell death 1 (PD-1)/programmed death ligand (PD-L)1 axis, this study…”
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Detection of KRAS G12/G13 Mutations in Cell Free-DNA by Droplet Digital PCR, Offers Prognostic Information for Patients with Advanced Non-Small Cell Lung Cancer by Michaelidou, Kleita, Koutoulaki, Chara, Mavridis, Konstantinos, Vorrias, Eleftherios, Papadaki, Maria A, Koutsopoulos, Anastasios V, Mavroudis, Dimitrios, Agelaki, Sofia

“…mutations are found in approximately one third of non-small cell lung cancer (NSCLC) patients. In this study, we aim to investigate whether G12/G13 mutant…”
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Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients by Boukovinas, Ioannis, Papadaki, Chara, Mendez, Pedro, Taron, Miquel, Mavroudis, Dimitris, Koutsopoulos, Anastasios, Sanchez-Ronco, Maria, Sanchez, Jose Javier, Trypaki, Maria, Staphopoulos, Eustathios, Georgoulias, Vassilis, Rosell, Rafael, Souglakos, John

“…Overexpression of RRM1 and RRM2 has been associated with gemcitabine resistance. BRCA1 overexpression increases sensitivity to paclitaxel and docetaxel. We…”
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Predictive value of BRCA1, ERCC1, ATP7B, PKM2, TOPOI, TOPΟ-IIA, TOPOIIB and C-MYC genes in patients with small cell lung cancer (SCLC) who received first line therapy with cisplatin and etoposide by Karachaliou, Niki, Papadaki, Chara, Lagoudaki, Eleni, Trypaki, Maria, Sfakianaki, Maria, Koutsopoulos, Anastasios, Mavroudis, Dimitris, Stathopoulos, Efstathios, Georgoulias, Vassilis, Souglakos, John

“…The aim of the study was to evaluate the predictive value of genes involved in the action of cisplatin-etoposide in Small Cell Lung Cancer (SCLC). 184 SCLC…”
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Autophagy proteins in prostate cancer: Relation with anaerobic metabolism and Gleason score by Giatromanolaki, Alexandra, M.D, Sivridis, Efthimios, M.D, Mendrinos, Savvas, M.D, Koutsopoulos, Anastasios V., M.D, Koukourakis, Michael I., M.D

“…Abstract Objectives Up-regulation of autophagy provides an important survival mechanism to normal and malignant cells residing in a hypoxic and unfavorable…”
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Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura by Lagoudaki, E., Mavridis, Charalampos, Georgiadis, George, Skamagkas, Iordanis, Heretis, Ioannis, Koutsopoulos, Anastasios V., Mamoulakis, Charalampos

“…Bladder leiomyomas (BLs) are extremely rare benign tumors of mesenchymal origin. The exact pathophysiological mechanisms that lead to their appearance remain…”
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Huge Cystic Lymphangioma of the Mediastinum Successfully Treated With Thoracoscopic Surgery by Lazopoulos, George, MD, PhD, Pavlopoulos, Dionisis, MD, PhD, Kambitakis, Emmanouil, MD, PhD, Koutsopoulos, Anastasios, MD, PhD, Chalkiadakis, George, MD, PhD

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Metastatic Ocular Melanoma Presenting as a Heart-Compressing Mediastinal Mass by Kiparakis, Michael, MD, Lazopoulos, George, MD, PhD, Koutsopoulos, Anastasios, MD, PhD, Gavalaki, Aikaterini, MD, Kampitakis, Emmanouil, MD, Chalkiadakis, George, MD, PhD

“…Ocular malignant melanoma is characterized by an unpredictable course, and metastases may develop, after a long disease-free interval, anywhere in the body…”
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Tumoral Expression of TXR1 and TSP1 Predicts Overall Survival of Patients with Lung Adenocarcinoma Treated with First-line Docetaxel-Gemcitabine Regimen by PAPADAKI, Chara, MAVROUDIS, Dimitris, TRYPAKI, Maria, KOUTSOPOULOS, Anastasios, STATHOPOULOS, Efstathios, HATZIDAKI, Dora, TSAKALAKI, Eleftheria, GEORGOULIAS, Vassilis, SOUGLAKOS, John

“…Purpose: In vitro data suggest that down-regulation of thrombospondin 1 ( TSP1 ) expression from TXR1 is associated with resistance to taxane-based…”
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Acute aortic occlusion due to tumor embolism in a patient with lung malignancy by Lioudaki, Stella, Kontopodis, Nikolaos, Palioudakis, Stefanos, Koutsopoulos, Anastasios V, Drositis, Ioannis, Ioannou, Christos V

“…Objectives: Acute lower limb ischemia caused by tumor embolization is rare, despite the fact that cancer is a common cause of hypercoagulability predisposing…”
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