Search Results - "KOTSUKI, H"

Diels-Alder Reaction of Thiophene: Dramatic Effects of High-Pressure/Solvent-Free Conditions by Kumamoto, Koji, Fukada, Isao, Kotsuki, Hiyoshizo

“…The extraordinary power of high‐pressure/solvent‐free conditions for the Diels–Alder reaction of thiophene has been established. For example, maleic anhydride…”
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Trifluoromethanesulfonic Acid, an Unusually Powerful Catalyst for the Michael Addition Reaction of β-Ketoesters under Solvent-Free Conditions by Kotsuki, Hiyoshizo, Arimura, Koji, Ohishi, Takeshi, Maruzasa, Ryosuke

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A New Class of Chiral Pyrrolidine−Pyridine Conjugate Base Catalysts for Use in Asymmetric Michael Addition Reactions by Ishii, Takaaki, Fujioka, Shingo, Sekiguchi, Yusuke, Kotsuki, Hiyoshizo

“…Direct catalytic asymmetric Michael addition reactions of ketones to nitroolefins using newly developed chiral pyrrolidine−pyridine conjugate bases as…”
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Synthesis of (+)-Conagenin by Matsukawa, Yohei, Isobe, Minoru, Kotsuki, Hiyoshizo, Ichikawa, Yoshiyasu

“…An efficient total synthesis of (+)-conagenin was achieved. The right fragment of conagenin, α-methylserine containing a quaternary stereocenter attached to…”
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Synthesis of (−)-(5 R,6 S)-6-acetoxyhexadecanolide based on l-proline-catalyzed asymmetric aldol reactions by Ikishima, Hideaki, Sekiguchi, Yusuke, Ichikawa, Yoshiyasu, Kotsuki, Hiyoshizo

“…A convenient method for proline-catalyzed asymmetric aldol reactions using synthons of straight-chain aliphatic aldehydes, and aldehydes bearing a 1,3-dithiane…”
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Unprecedented Hydrothermal Reaction of O-Phenylaniline and Related Derivatives with Cyclic Ketones. A Novel Approach to the Construction of Phenanthridine and Quinoline Ring Systems by Mehta, Barun K, Yanagisawa, Kazumichi, Shiro, Motoo, Kotsuki, Hiyoshizo

“…A new method for synthesizing phenanthridine and its related compounds was developed using the condensation of o-phenylaniline and its homologues with cyclic…”
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A new practical method for the synthesis of unsymmetrical ureas via high-pressure-promoted condensation of 2,2,2-trichloroethyl carbamates (Troc-carbamates) with amines by Azad, Saleha, Kumamoto, Koji, Uegaki, Kaoru, Ichikawa, Yoshiyasu, Kotsuki, Hiyoshizo

“…A new practical method for the synthesis of unsymmetrical ureas was achieved by condensation between 2,2,2-trichloroethyl carbamates (Troc-carbamates) and…”
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Solvent-free organic reactions on silica gel supports. Facile transformation of epoxides to β-halohydrins with lithium halides by Kotsuki, Hiyoshizo, Shimanouchi, Tomoyasu, Ohshima, Reiji, Fujiwara, Shunsuke

“…The reaction of epoxides with lithium halides was efficiently promoted on the surface of silica gel in the absence of any solvent to give the corresponding…”
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Multicomponent Strecker Reaction under High Pressure by Matsumoto, Kiyoshi, Kim, Jong Chul, Iida, Hirokazu, Hamana, Hiroshi, Kumamoto, Koji, Kotsuki, Hiyoshizo, Jenner, Gérard

“…For the first time, uncatalyzed, high‐pressure (0.6 GPa) reactions with ketones have proven to be a powerful way to perform the three‐component Strecker…”
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High-yielding TfOH-catalyzed condensation of phenols with aromatic aldehydes at high pressure. A model synthesis of the benzylidene biphenol key skeleton of blepharismins by Ohishi, Takeshi, Kojima, Tomoyuki, Matsuoka, Tatsuomi, Shiro, Motoo, Kotsuki, Hiyoshizo

“…An approach to the benzylidene biphenol key component of blepharismins, photoreceptor pigments isolated from Blepharisma japonicum, is reported. This method…”
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A facile conversion of epoxides to β-halohydrins with silica gel-supported lithium halides by Kotsuki, Hiyoshizo, Shimanouchi, Tomoyasu

“…A variety of epoxides are efficiently converted to the corresponding β-halohydrins with lithium halides supported on silica gel in dry media. Graphic…”
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High-pressure-promoted condensation of isothiocyanates with aminopyridines: efficient synthesis of pyridine–thiourea conjugates as building blocks for hydrogen-bonding receptors by Kumamoto, Koji, Misawa, Yoshihiro, Tokita, Sumio, Kubo, Yuji, Kotsuki, Hiyoshizo

“…New N-pyridinothiourea derivatives have been prepared by the high-pressure-promoted condensation of isothiocyanates with aminopyridines under uncatalyzed…”
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A novel aromatic alkylation of anilines with cyclic and acyclic ketones under hydrothermal conditions by Mehta, Barun K., Kumamoto, Koji, Yanagisawa, Kazumichi, Kotsuki, Hiyoshizo

“…A novel aromatic ring-alkylation was achieved by condensation between aniline·HCl salts and cyclic or acyclic ketones under hydrothermal conditions…”
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Are Multicomponent Strecker Reactions of Diketones with Diamines under High Pressure Amenable to Heterocyclic Synthesis? by Matsumoto, Kiyoshi, Kumamoto, Koji, Iida, Hirokazu, Hamana, Hiroshi, Kotsuki, Hiyoshizo

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Ytterbium(III) trifluoromethanesulfonate catalyzed high pressure reaction of epoxides with indole. An enantioselective synthesis of (+)-diolmycin A2 by Kotsuki, Hiyoshizo, Teraguchi, Masahiro, Shimomoto, Nami, Ochi, Masamitsu

“…Epoxide opening reactions with indole are efficiently accelerated under high pressure conditions in the presence of a catalytic amount of ytterbium(III)…”
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The structure of amoorastatone and the cytotoxic limonoid 12-hydroxyamoorastatin by Polonsky, J, Varon, Z, Marazano, C, Arnoux, B, Pettit, G R, Schmid, J M, Ochi, M, Kotsuki, H

“…2 new limonoid-type terpenes have been isolated from an aqueous extract of seeds produced by the Eastern Himalayan (India) plant Aphanamixis grandifolia B1. By…”
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A New Enantioselective Total Synthesis of AI-77-B by Kotsuki, Hiyoshizo, Araki, Tomohiro, Miyazaki, Aya, Iwasaki, Mitsuhiro, Datta, Probal K

“…An enantioselective total synthesis of AI-77-B (1), a gastroprotective substance isolated from a culture broth of Bacillus pumilus AI-77, was performed in high…”
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A new practical method for regioselective nucleophilic aromatic alkylation of ortho- or para-methoxy-substituted aromatic esters with Grignard reagents by Kojima, Tomoyuki, Ohishi, Takeshi, Yamamoto, Izumi, Matsuoka, Tatsuomi, Kotsuki, Hiyoshizo

“…A new practical method for the regioselective nucleophilic aromatic alkylation of o- or p-methoxy-substituted aromatic carboxylic acids via their…”
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Synthesis of Novel Chiral Diazole Derivative Ligands for the Enantioselective Addition of Diethylzinc to Benzaldehyde by Kotsuki, Hiyoshizo, Wakao, Masahiro, Hayakawa, Hiroyuki, Shimanouchi, Tomoyasu, Shiro, Motoo

“…The high-pressure-promoted reaction of epoxides with pyrazoles and imidazoles provided access to a variety of chiral diazole derivative ligands such as 11−23…”
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A new facile method for the chemoselective reductive transformation of azides to N-( tert-butoxycarbonyl)amines by Kotsuki, Hiyoshizo, Ohishi, Takeshi, Araki, Tomohiro

“…A new chemoselective procedure for the reductive transformation of organic azides to the corresponding N-( tert-butoxycarbonyl)amino derivatives using…”
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