Search Results - "KOSOWER, N. S"

Caspase-1 activity is required for neuronal differentiation of PC12 cells: Cross-talk between the caspase and calpain systems by Vaisid, T., Kosower, N.S., Barnoy, S.

“…Previously, we have found that caspase-1 activity is increased during myoblast differentiation to myotubes. Here we show that caspase-1 activity is required…”
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Regulation of calpain and calpastatin in differentiating myoblasts: mRNA levels, protein synthesis and stability by Barnoy, S, Supino-Rosin, L, Kosower, N S

“…Calpain (Ca(2+)-dependent intracellular protease)-induced proteolysis has been considered to play a role in myoblast fusion to myotubes. We found previously…”
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Thiol–disulfide status of human sperm proteins by Seligman, J, Kosower, N S, Weissenberg, R, Shalgi, R

“…The thiol–disulfide status in proteins of human spermatozoa categorized as normozoospermic, teratozoospermic and asthenozoospermic was examined. Washed…”
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Dynamics of the thiol status of rat spermatozoa during maturation: analysis with the fluorescent labeling agent monobromobimane by SHALGI, R, SELIGMAN, J, KOSOWER, N. S

“…Mammalian spermatozoa undergo maturation as they pass through the epididymis. Maturation is accompanied by the oxidation of thiols to disulfides. Disulfides…”
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Calpastatin overexpression attenuates amyloid-β-peptide toxicity in differentiated PC12 cells by Vaisid, T, Barnoy, S, Kosower, N.S

“…Abstract Amyloid β peptide (Aβ) plays a major role in the pathogenesis of Alzheimer's disease (AD). Aβ is toxic to neurons, possibly through causing initial…”
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Effects of caput ligation on rat sperm and epididymis: protein thiols and fertilizing ability by SELIGMAN, J, KOSOWER, N. S, SHALGI, R

“…Mammalian spermatozoa mature while passing through the epididymis. Maturation is accompanied by thiol oxidation to disulfides. In rats, sperm become motile and…”
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Evidence for function of the ferredoxin/thioredoxin system in the reductive activation of target enzymes of isolated intact chloroplasts by Crawford, N A, Droux, M, Kosower, N S, Buchanan, B B

“…Results obtained with isolated intact chloroplasts maintained aerobically under light and dark conditions confirm earlier findings with reconstituted enzyme…”
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Constitutive heterochromatin of chromosome 1 and Duffy blood group alleles in schizophrenia by Kosower, N S, Gerad, L, Goldstein, M, Parasol, N, Zipser, Y, Ragolsky, M, Rozencwaig, S, Elkabetz, E, Abramovitch, Y, Lerer, B

“…Cytogenetic analysis was carried out in unrelated schizophrenic patients, unrelated controls and patients and family members in multiplex families. The size…”
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Band 3 protein degradation by calpain is enhanced in erythrocytes of old people by SCHWARZ-BEN MEIR, N, GLASER, T, KOSOWER, N. S

“…Band 3 protein is a major erythrocyte transmembrane glycoprotein. We compared the degradation of band 3 protein by calpain I (a cytoplasmic,…”
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Diamide: an oxidant probe for thiols by Kosower, N S, Kosower, E M

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Altered properties of erythrocytes in the aged by Kosower, N S

“…Erythrocytes in the aged have a decreased life span. The properties of the red blood cells of old individuals are compared to those of the cells of young…”
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Sperm analysis by flow cytometry using the fluorescent thiol labeling agent monobromobimane by Seligman, J, Shalgi, R, Oschry, Y, Kosower, N S

“…The fluorescent labeling agent monobromobimane (mBBr) was used to label thiols and disulfides (after reduction of sperm disulfides by dithiothreitol) in intact…”
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Thiol-disulfide status and acridine orange fluorescence of mammalian sperm nuclei by Kosower, N. S, Katayose, H, Yanagimachi, R

“…The relationship between thiol‐disulfide status and acridine orange fluorescence of testicular, epididymal, and ejaculated spermatozoa in several mammalian…”
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A novel mutation in the coding sequence of the FYB allele of the Duffy chemokine receptor gene is associated with an altered erythrocyte phenotype by PARASOL, N, REID, M, RIOS, M, CASTILHO, L, HARARI, I, KOSOWER, N. S

“…The Duffy blood group system is of clinical and biological significance. Antibodies to Duffy antigens are responsible for some cases of transfusion…”
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Calpastatin in erythrocytes of young and old individuals by Schwarz-Benmeir, N, Glaser, T, Barnoy, S, Kosower, N S

“…To gain knowledge about the behaviour of calpastatin (the specific inhibitor of the Ca(2+)-dependent thiol protease calpain) in the intact cell, we analysed…”
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Bimane Fluorescent Labels: Labeling of Normal Human Red Cells under Physiological Conditions by Kosower, Nechama S., Kosower, Edward M., Newton, Gerald L., Ranney, Helen M.

“…The bimane fluorescent labels, monobromobimane, dibromobimane, and monobromotrimethylammoniobimane, are derivatives of…”
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Ferredoxin-thioredoxin reductase: a catalytically active dithiol group links photoreduced ferredoxin to thioredoxin functional in photosynthetic enzyme regulation by Droux, M, Miginiac-Maslow, M, Jacquot, J P, Gadal, P, Crawford, N A, Kosower, N S, Buchanan, B B

“…The mechanism by which the ferredoxin-thioredoxin system activates the target enzyme, NADP-malate dehydrogenase, was investigated by analyzing the sulfhydryl…”
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Overexpression of calpastatin inhibits L8 myoblast fusion by Barnoy, Sivia, Maki, Masatoshi, Kosower, Nechama S.

“…The formation of skeletal muscle fibers involves cessation of myoblast division, myoblast alignment, and fusion to multinucleated myofibers. Calpain is one of…”
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Duffy Antigen/Receptor for Chemokines (DARC): Genotypes in Ashkenazi and Non-Ashkenazi Jews in Israel by PARASOL, NIVA, COHEN, NECHAMA, ZEMISHLANY, ZVI, LERER, BERNARD, KOSOWER, NECHAMA S.

“…Duffy genotypes were studied in Ashkenazi and non-Ashkenazi groups in Israel. The prevalence of the genotypes for the known polymorphic FF*A, FY*B, and…”
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Localization of thiol and disulfide groups in guinea pig spermatozoa during maturation and capacitation using bimane fluorescent labels by HUANG, T. T. F, KOSOWER, N. S, YANAGIMACHI, R

“…The distribution of thiols and disulfides in the guinea pig spermatozoon during maturation and capacitation was studied using both membrane-permeable (mBBr)…”
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