Search Results - "KORDEK, Radzislaw"

Raman ‘optical biopsy’ of human breast cancer by Abramczyk, Halina, Brozek-Pluska, Beata, Surmacki, Jakub, Jablonska-Gajewicz, Joanna, Kordek, Radzisław

“…Raman imaging (RI) is a novel method of medical diagnostics of human breast cancer and has a potential to become a routine optical biopsy. Up to date the…”
Get full text

Walnut Oil Alleviates Intestinal Inflammation and Restores Intestinal Barrier Function in Mice by Bartoszek, Adrian, Makaro, Adam, Bartoszek, Agnieszka, Kordek, Radzisław, Fichna, Jakub, Salaga, Maciej

“…Ulcerative colitis belongs to inflammatory bowel diseases, which is a group of chronic disorders of the gastrointestinal tract. It is a debilitating condition…”
Get full text

ABCG2 Gene and ABCG2 Protein Expression in Colorectal Cancer-In Silico and Wet Analysis by Sałagacka-Kubiak, Aleksandra, Zawada, Dawid, Saed, Lias, Kordek, Radzisław, Jeleń, Agnieszka, Balcerczak, Ewa

“…ABCG2 (ATP-binding cassette superfamily G member 2) is a cell membrane pump encoded by the gene. ABCG2 can protect cells against compounds initiating and/or…”
Get full text

AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice by Zatorski, Hubert, Salaga, Maciej, Zielińska, Marta, Majchrzak, Kinga, Binienda, Agata, Kordek, Radzisław, Małecka-Panas, Ewa, Fichna, Jakub

“…Introduction: Adiponectin is a hormone secreted by adipocytes, which exhibits insulin-sensitizing and anti-inflammatory properties and acts through adiponectin…”
Get full text

Assessment of the TGFB1 gene expression and methylation status of the promoter region in patients with colorectal cancer by Wodziński, Damian, Wosiak, Agnieszka, Pietrzak, Jacek, Świechowski, Rafał, Kordek, Radzisław, Balcerczak, Ewa

“…The aim of this study was to evaluate the expression of the TGFB1 gene encoding the TGF- β 1 cytokine in 64 patients, and then to compare it with…”
Get full text

Intratumor heterogeneity and tissue distribution of KRAS mutation in non-small cell lung cancer: implications for detection of mutated KRAS oncogene in exhaled breath condensate by Kordiak, Jacek, Szemraj, Janusz, Grabska-Kobylecka, Izabela, Bialasiewicz, Piotr, Braun, Marcin, Kordek, Radzisław, Nowak, Dariusz

“…Purpose Mutated KRAS oncogene in exhaled breath condensate (EBC) can be a genetic marker of non-small cell lung cancer (NSCLC). However, a possibility of…”
Get full text

Intertumoral Heterogeneity of Primary Breast Tumors and Synchronous Axillary Lymph Node Metastases Reflected in IHC-Assessed Expression of Routine and Nonstandard Biomarkers by Kuncman, Wojciech, Orzechowska, Magdalena, Kuncman, Łukasz, Kordek, Radzisław, Taran, Katarzyna

“…Breast cancer (BC) remains a significant healthcare challenge. Routinely, the treatment strategy is determined by immunohistochemistry (IHC)-based assessment…”
Get full text

FGFR2-Driven Signaling Counteracts Tamoxifen Effect on ERα-Positive Breast Cancer Cells by Turczyk, Lukasz, Kitowska, Kamila, Mieszkowska, Magdalena, Mieczkowski, Kamil, Czaplinska, Dominika, Piasecka, Dominika, Kordek, Radzisław, Skladanowski, Andrzej C., Potemski, Piotr, Romanska, Hanna M., Sadej, Rafal

“…Signaling mediated by growth factors receptors has long been suggested as one of the key factors responsible for failure of endocrine treatment in breast…”
Get full text

G protein-coupled estrogen receptor mediates anti-inflammatory action in Crohn’s disease by Jacenik, Damian, Zielińska, Marta, Mokrowiecka, Anna, Michlewska, Sylwia, Małecka-Panas, Ewa, Kordek, Radzisław, Fichna, Jakub, Krajewska, Wanda M.

“…Estrogens exert immunomodulatory action in many autoimmune diseases. Accumulating evidence highlights the meaningful impact of estrogen receptors in physiology…”
Get full text

The Anti-Inflammatory Effect of Acidic Mammalian Chitinase Inhibitor OAT-177 in DSS-Induced Mouse Model of Colitis by Mazur, Marzena, Włodarczyk, Jakub, Świerczyński, Mikołaj, Kordek, Radzisław, Grzybowski, Marcin M, Olczak, Jacek, Fichna, Jakub

“…Inflammatory bowel diseases (IBD) are chronic and relapsing gastrointestinal disorders, where a significant proportion of patients are unresponsive or lose…”
Get full text

New Class of Anti-Inflammatory Therapeutics Based on Gold (III) Complexes in Intestinal Inflammation-Proof of Concept Based on In Vitro and In Vivo Studies by Krajewska, Julia B, Włodarczyk, Jakub, Jacenik, Damian, Kordek, Radzisław, Taciak, Przemysław, Szczepaniak, Remigiusz, Fichna, Jakub

“…Inflammatory bowel diseases (IBD) are at the top of the worldwide rankings for gastrointestinal diseases as regards occurrence, yet efficient and…”
Get full text

Analysis of Human Colon by Raman Spectroscopy and Imaging-Elucidation of Biochemical Changes in Carcinogenesis by Brozek-Pluska, Beata, Musial, Jacek, Kordek, Radzislaw, Abramczyk, Halina

“…Noninvasive Raman imaging of non-fixed and unstained human colon tissues based on vibrational properties of noncancerous and cancerous samples can effectively…”
Get full text

Experimental colitis in mice is attenuated by topical administration of chlorogenic acid by Zatorski, Hubert, Sałaga, Maciej, Zielińska, Marta, Piechota-Polańczyk, Aleksandra, Owczarek, Katarzyna, Kordek, Radzisław, Lewandowska, Urszula, Chen, Chunqiu, Fichna, Jakub

“…Epidemiological data suggest that the consumption of polyphenol-rich foods reduces the incidence of cancer, coronary heart disease, and inflammation…”
Get full text

Empagliflozin attenuates intestinal inflammation through suppression of nitric oxide synthesis and myeloperoxidase activity in in vitro and in vivo models of colitis by Makaro, Adam, Świerczyński, Mikołaj, Pokora, Kacper, Sarniak, Barbara, Kordek, Radzisław, Fichna, Jakub, Salaga, Maciej

“…Inflammatory bowel diseases (IBD) are characterized by chronic and relapsing inflammation affecting the gastrointestinal (GI) tract. The incidence and…”
Get full text

Activation of Free Fatty Acid Receptor 4 Affects Intestinal Inflammation and Improves Colon Permeability in Mice by Salaga, Maciej, Bartoszek, Adrian, Binienda, Agata, Krajewska, Julia B, Fabisiak, Adam, Mosińska, Paula, Dziedziczak, Katarzyna, Niewinna, Karolina, Talar, Marcin, Tarasiuk, Aleksandra, Kordek, Radzisław, Fichna, Jakub

“…Diet is considered an important trigger in inflammatory bowel diseases (IBD), as feeding habits can affect intestinal permeability and clearance of bacterial…”
Get full text

FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors - implications for therapy of luminal breast cancer by Piasecka, Dominika, Braun, Marcin, Kitowska, Kamila, Mieczkowski, Kamil, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna

“…Stromal stimuli mediated by growth factor receptors, leading to ligand-independent activation of steroid hormone receptors, have long been implicated in…”
Get full text

MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients by Jesionek-Kupnicka, Dorota, Braun, Marcin, Trąbska-Kluch, Berenika, Czech, Joanna, Szybka, Małgorzata, Szymańska, Bożena, Kulczycka-Wojdala, Dominika, Bieńkowski, Michał, Kordek, Radzisław, Zawlik, Izabela

“…and alterations play a crucial role in glioblastoma (GB) pathogenesis. and function is affected by several pathologic mechanisms, such as point mutations or…”
Get full text

Raman spectroscopy and imaging: applications in human breast cancer diagnosis by Brozek-Pluska, Beata, Musial, Jacek, Kordek, Radzislaw, Bailo, Elena, Dieing, Thomas, Abramczyk, Halina

“…The applications of spectroscopic methods in cancer detection open new possibilities in early stage diagnostics. Raman spectroscopy and Raman imaging represent…”
Get more information

Characterization of the Synergistic Effect between Ligands of Opioid and Free Fatty Acid Receptors in the Mouse Model of Colitis by Binienda, Agata, Makaro, Adam, Talar, Marcin, Krajewska, Julia B., Tarasiuk, Aleksandra, Bartoszek, Adrian, Fabisiak, Adam, Mosińska, Paula, Niewinna, Karolina, Dziedziczak, Katarzyna, Świerczyński, Mikołaj, Kordek, Radzisław, Salaga, Maciej, Fichna, Jakub

“…Background: Recent studies suggest that lipids, including free fatty acids (FFAs), are necessary for proper μ opioid receptor (MOR) binding and that activation…”
Get full text

FGF7/FGFR2–JunB signalling counteracts the effect of progesterone in luminal breast cancer by Mieczkowski, Kamil, Kitowska, Kamila, Braun, Marcin, Galikowska‐Bogut, Barbara, Gorska‐Arcisz, Monika, Piasecka, Dominika, Stawiski, Konrad, Zaczek, Anna J., Nejc, Dariusz, Kordek, Radzisław, Romanska, Hanna M., Sadej, Rafal

“…We have recently demonstrated that fibroblast growth factor receptor 2 (FGFR2)‐mediated signalling alters progesterone receptor (PR) activity and response of…”
Get full text