Search Results - "KOOPMAN, Jaap"
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Molecular characterization of eukaryotic polysialyltransferase-1
Published in Nature (London) (23-02-1995)“…Polysialic acid (PSA) is a dynamically regulated product of post-translational modification of the neural cell adhesion molecule, NCAM. Presence of the large…”
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2
Interplay of fibrinogen αEC globular domains and factor XIIIa cross-linking dictates the extensibility and strain stiffening of fibrin networks
Published in Journal of thrombosis and haemostasis (01-03-2024)“…Fibrinogen is a plasma protein forming the fibrin scaffold of blood clots. Its mechanical properties therefore affect the risk of bleeding as well as…”
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3
Interplay of fibrinogen α E C globular domains and factor XIIIa cross-linking dictates the extensibility and strain stiffening of fibrin networks
Published in Journal of thrombosis and haemostasis (01-03-2024)“…Fibrinogen is a plasma protein forming the fibrin scaffold of blood clots. Its mechanical properties therefore affect the risk of bleeding as well as…”
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4
Fibrinogen γ′ promotes host survival during Staphylococcus aureus septicemia in mice
Published in Journal of thrombosis and haemostasis (01-08-2023)“…Staphylococcus aureus is a common gram-positive bacterium that is the causative agent for several human diseases, including sepsis. A key virulence mechanism…”
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5
A Human Fibrinogen Variant with Impaired StaphylococcusAureus Binding Function Promotes Host Survival during Septicemia in Mice
Published in Blood (29-11-2018)“…Staphylococcus aureus is a common gram-positive bacterium that is a causative agent for a number of life-threatening diseases. The emergence of antibiotic…”
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6
Mitogenic Effects of Urokinase on Melanoma Cells Are Independent of High Affinity Binding to the Urokinase Receptor
Published in The Journal of biological chemistry (11-12-1998)“…The structural and functional properties of the urokinase-type plasminogen activator (u-PA) that are involved in the mitogenic effect of this proteolytic…”
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Fibrinogen Bastia (gamma 318 Asp-->Tyr) a novel abnormal fibrinogen characterized by defective fibrin polymerization
Published in Thrombosis and haemostasis (01-12-1999)“…A new congenital dysfibrinogen, Fibrinogen Bastia, was discovered in a 20-year-old woman with no clinical symptoms. The plasma thrombin-clotting time was…”
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8
Dynamic arm study: quantitative description of upper extremity function and activity of boys and men with duchenne muscular dystrophy
Published in Journal of neuroengineering and rehabilitation (26-05-2017)“…Therapeutic management of upper extremity (UE) function of boys and men with Duchenne Muscular Dystrophy (DMD) requires sensitive and objective assessment…”
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Unraveling the Link between Nonlinear Mechanics, Microstructure, and Molecular Packing of Fibrin
Published in Biophysical journal (27-01-2015)Get full text
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10
Levels of Fibrinogen Variants Are Altered in Severe COVID-19
Published in TH open : companion journal to thrombosis and haemostasis (01-07-2023)“…Fibrinogen variants as a result of alternative messenger RNA splicing or protein degradation can affect fibrin(ogen) functions. The levels of these variants…”
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11
Fibrinogen reduction and coagulation in cardiac surgery: an investigational study
Published in Blood coagulation & fibrinolysis (01-09-2015)“…Fibrinogen as precursor of fibrin plays an essential role in clot formation. There are three main mechanisms associated with a reduction in fibrinogen…”
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12
Doxycycline Inhibits Collagen Synthesis by Bovine Chondrocytes Cultured in Alginate
Published in Biochemical and biophysical research communications (08-08-1997)“…Doxycycline is known for its ability to inhibit matrix metalloproteinases (MMPs), a family of enzymes that play a role in cartilage breakdown in arthritides…”
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13
The use of PEGT/PBT as a dermal scaffold for skin tissue engineering
Published in Biomaterials (01-07-2004)“…Human skin equivalents (HSEs) were engineered using biodegradable-segmented copolymer PEGT/PBT as a dermal scaffold. As control groups, fibroblast-populated…”
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14
Safety and efficacy of a novel, dry powder fibrin sealant for hemostasis in hepatic resection
Published in Digestive surgery (01-01-2014)“…Fibrocaps is a dry powder fibrin sealant containing human plasma-derived fibrinogen and thrombin. The safety, efficacy, and application methods for Fibrocaps…”
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Aberrant fibrin formation and cross-linking of fibrinogen Nieuwegein, a variant with a shortened Aα-chain, alters endothelial capillary tube formation
Published in Blood (15-02-2001)“…Abstract A congenital dysfibrinogenemia, fibrinogenNieuwegein, was discovered in a young man without any thromboembolic complications or bleeding. A homozygous…”
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16
Fibrinogen Marburg: a homozygous case of dysfibrinogenemia, lacking amino acids A alpha 461-610 (Lys 461 AAA-->stop TAA)
Published in Blood (15-10-1992)“…In the A alpha-chain gene coding for an abnormal fibrinogen (fibrinogen Marburg) we identified a single base substitution (A-->T) that changes the codon A…”
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Abnormal Fibrinogens IJmuiden (B(beta)ARg(14)(gives)Cys) and Nijmegen (B(beta)Arg(44)(gives)Cys)Form Disulfide-Linked Fibrinogen-Albumin Complexes
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-1992)“…The molecular defects in two congenital abnormal fibrinogens, IJmuiden and Nijmegen, were determined by sequence analysis of genomic DNA amplified by the…”
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Fibrinogen Alès: a homozygous case of dysfibrinogenemia (γ-Asp330 →Val) characterized by a defective fibrin polymerization site “a”
Published in Blood (15-11-2000)“…Congenital homozygous dysfibrinogenemia was diagnosed in a man with a history of 2 thrombotic strokes before age 30. His hemostatic profile was characterized…”
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Fibrinogen Alès: a homozygous case of dysfibrinogenemia (γ-Asp330 →Val) characterized by a defective fibrin polymerization site “a”
Published in Blood (15-11-2000)“…Abstract Congenital homozygous dysfibrinogenemia was diagnosed in a man with a history of 2 thrombotic strokes before age 30. His hemostatic profile was…”
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20
Fibrinogen Alès: a homozygous case of dysfibrinogenemia (γ-Asp330 →Val) characterized by a defective fibrin polymerization site “a”
Published in Blood (15-11-2000)“…Congenital homozygous dysfibrinogenemia was diagnosed in a man with a history of 2 thrombotic strokes before age 30. His hemostatic profile was characterized…”
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