Search Results - "KONO, Takako"

Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies by Hilton, John, Gelmon, Karen, Bedard, Philippe L., Tu, Dongsheng, Xu, Hong, Tinker, Anna V., Goodwin, Rachel, Laurie, Scott A., Jonker, Derek, Hansen, Aaron R., Veitch, Zachary W., Renouf, Daniel J., Hagerman, Linda, Lui, Hongbo, Chen, Bingshu, Kellar, Deb, Li, Irene, Lee, Sung-Eun, Kono, Takako, Cheng, Brian Y. C., Yap, Damian, Lai, Daniel, Beatty, Sean, Soong, John, Pritchard, Kathleen I., Soria-Bretones, Isabel, Chen, Eric, Feilotter, Harriet, Rushton, Moira, Seymour, Lesley, Aparicio, Samuel, Cescon, David W.

“…CX-5461 is a G-quadruplex stabilizer that exhibits synthetic lethality in homologous recombination-deficient models. In this multicentre phase I trial in…”
Get full text

Single-cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers by Kabeer, Farhia, Tran, Hoa, Andronescu, Mirela, Singh, Gurdeep, Lee, Hakwoo, Salehi, Sohrab, Wang, Beixi, Biele, Justina, Brimhall, Jazmine, Gee, David, Cerda, Viviana, O'Flanagan, Ciara, Algara, Teresa, Kono, Takako, Beatty, Sean, Zaikova, Elena, Lai, Daniel, Lee, Eric, Moore, Richard, Mungall, Andrew J, Williams, Marc J, Roth, Andrew, Campbell, Kieran R, Shah, Sohrab P, Aparicio, Samuel

“…The encoding of cell intrinsic drug resistance states in breast cancer reflects the contributions of genomic and non-genomic variations and requires accurate…”
Get full text

Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Fusion Imaging for Prediction of Metastasis to Sentinel and Nonsentinel Nodes in Patients with Clinically Node-Negative Breast Cancer by Yamagishi, Yoji, Yamasaki, Tamio, Ishida, Jiro, Moriya, Tomoyuki, Einama, Takahiro, Koiwai, Tomomi, Fukumura-Koga, Makiko, Kono, Takako, Hayashi, Katsumi, Ueno, Hideki, Yamamoto, Junji, Tsuda, Hitoshi

“…Purpose 18 F-Fluorodeoxyglucose positron emission tomography/computed tomography fusion imaging ( 18 F-FDG PET/CT) is an important diagnostic tool in breast…”
Get full text

Tumor-to-tumor metastasis from lung cancer: a clinicopathological postmortem study by Matsukuma, Susumu, Kono, Takako, Takeo, Hiroaki, Hamakawa, Yusuke, Sato, Kimiya

“…This study examined 47 cases of lung cancer concomitant with other tumors and found eight cases (17 %) with nine foci of tumor-to-tumor metastasis, defined as…”
Get full text

Aquaporin 3 Expression in Endometrioid Carcinoma of the Uterine Body Correlated With Early Stage and Lower Grade by Watanabe, Takanori, Sato, Kimiya, Kono, Takako, Yamagishi, Yoji, Kumazawa, Fumihisa, Miyamoto, Morikazu, Takano, Masashi, Tsuda, Hitoshi

“…Aquaporins (AQPs) are a family of transmembrane water channel proteins distributed in various human tissues. Recent studies revealed that AQPs play important…”
Get full text

Dual time point 18F-fluorodeoxyglucose positron emission tomography/computed tomography fusion imaging (18F-FDG PET/CT) in primary breast cancer by YAMAGISHI, Yoji, KOIWAI, Tomomi, YAMASAKI, Tamio, EINAMA, Takahiro, FUKUMURA, Makiko, HIRATSUKA, Miyuki, KONO, Takako, HAYASHI, Katsumi, ISHIDA, Jiro, UENO, Hideki, TSUDA, Hitoshi

“…Background To evaluate the clinicopathological and prognostic significance of the percentage change between maximum standardized uptake value (SUV.sub.max) at…”
Get full text

Primary pulmonary myxoid sarcoma with EWSR1‐CREB1 fusion, resembling extraskeletal myxoid chondrosarcoma: Case report with a review of Literature by Matsukuma, Susumu, Hisaoka, Masanori, Obara, Kiyohaya, Kono, Takako, Takeo, Hiroaki, Sato, Kimiya, Hata, Yoshinobu

“…Reported herein is an extremely rare case of primary pulmonary myxoid sarcoma (PPMS). A 31‐year‐old man presented with a 2.7 cm‐sized pulmonary tumor…”
Get full text

Comparison between AJCC 8th prognostic stage and UICC anatomical stage in patients with primary breast cancer: a single institutional retrospective study by Tanaka, Ryo, Yamagishi, Yoji, Koiwai, Tomomi, Kono, Takako, Fukumura-Koga, Makiko, Einama, Takahiro, Yamasaki, Tamio, Sato, Kimiya, Ueno, Hideki, Kishi, Yoji, Tsuda, Hitoshi

“…Background The 8th edition American Joint Committee on Cancer (AJCC) proposed a prognostic stage (PS), which included not only anatomical factors, but also…”
Get full text

Circulating tumour mutation detection in triple-negative breast cancer as an adjunct to tissue response assessment by Zaikova, Elena, Cheng, Brian Y. C., Cerda, Viviana, Kong, Esther, Lai, Daniel, Lum, Amy, Bates, Cherie, den Brok, Wendie, Kono, Takako, Bourque, Sylvie, Chan, Angela, Feng, Xioalan, Fenton, David, Gurjal, Anagha, Levasseur, Nathalie, Lohrisch, Caroline, Roberts, Sarah, Shenkier, Tamara, Simmons, Christine, Taylor, Sara, Villa, Diego, Miller, Ruth, Aguirre-Hernandez, Rosalia, Aparicio, Samuel, Gelmon, Karen

“…Circulating tumour DNA (ctDNA) detection via liquid biopsy is an emerging alternative to tissue biopsy, but its potential in treatment response monitoring and…”
Get full text

Intraepithelial lymphocytes are indicators of better prognosis in surgically resected endometrioid-type endometrial carcinomas at early and advanced stages by Kono-Sato, Takako, Miyai, Kosuke, Yamagishi, Yoji, Miyamoto, Morikazu, Takano, Masashi, Matsukuma, Susumu, Sato, Kimiya, Tsuda, Hitoshi

“…Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) may be useful prognostic indicators in endometrial cancer. However, standardized…”
Get full text

Fat cells and membranous fat necrosis of aortic valves: A clinicopathological study by Matsukuma, Susumu, Takeo, Hiroaki, Kono, Takako, Sato, Kimiya

“…We examined 152 aortic valves (AVs), which included 82 postmortem non‐dysfunctional AVs (nd‐AVs) and 70 surgically removed dysfunctional AVs showing aortic…”
Get full text

Observation of Angiolymphoid Hyperplasia with Eosinophilia (ALHE) at Three Arterial Sites and Its Association with Membranous Nephropathy by Ito, Seigo, Oda, Takashi, Matsuo, Akiko, Takechi, Hanako, Uchida, Takahiro, Watanabe, Atsushi, Kono, Takako, Shimazaki, Hideyuki, Tamai, Seiichi, Oshima, Naoki, Kumagai, Hiroo

“…We herein report a case involving the systemic presentation of angiolymphoid hyperplasia with eosinophilia (ALHE) in association with membranous nephropathy…”
Get full text

Role of tubulointerstitial plasmin in the progression of IgA nephropathy by Uchida, Takahiro, Oda, Takashi, Takechi, Hanako, Matsubara, Hidehito, Watanabe, Atsushi, Yamamoto, Kojiro, Oshima, Naoki, Sakurai, Yutaka, Kono, Takako, Shimazaki, Hideyuki, Tamai, Seiichi, Kumagai, Hiroo

“…Background Plasmin has recently been reported to be associated with renal fibrosis in experimental models, but its role in human renal diseases is unclear…”
Get full text

VEGF secretion from Epstein-Barr virus-infected cells as a cause of severe anasarca in a patient with angioimmunoblastic T-cell lymphoma by Takada, Kohei, Kawamura, Toshikuni, Kono, Takako, Sone, Takehiro, Ogata, Hiraku, Saito, Keita, Okada, Yosuke, Tachi, Noriaki, Teramoto, Masahiro, Kato, Shoichiro, Maekawa, Takaaki, Kobayashi, Shinichi, Sato, Ken, Sato, Kimiya, Kimura, Fumihiko

“…A 69-year-old woman presented to National Defense Medical College hospital for suspected nephrotic syndrome due to weight gain of 30 kg in 3 weeks and…”
Get more information

Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung by Ogata, Sho, Kameda, Koji, Kono, Takako, Ozeki, Yuichi, Hashimoto, Hiroshi, Tominaga, Susumu, Nakanishi, Kuniaki

“…Little is known about the association between the atypical adenomatous hyperplasia (AAH)-adenocarcinoma in situ sequence of the lung and endoplasmic…”
Get full text

Aberrant cytokeratin 7 expression of centrilobular hepatocytes: a clinicopathological study by Matsukuma, Susumu, Takeo, Hiroaki, Kono, Takako, Nagata, Yuiko, Sato, Kimiya

“…Matsukuma S, Takeo H, Kono T, Nagata Y & Sato K 
(2012) Histopathology 61, 857–862 Aberrant cytokeratin 7 expression of centrilobular hepatocytes: a…”
Get full text

Clonal fitness inferred from timeseries modeling of single cell cancer genomes by Salehi, Sohrab, Kabeer, Farhia, Ceglia, Nicholas, Andronescu, Mirela, Williams, Marc J., Campbell, Kieran R., Masud, Tehmina, Wang, Beixi, Biele, Justina, Brimhall, Jazmine, Gee, David, Lee, Hakwoo, Ting, Jerome, Zhang, Allen W., Tran, Hoa, O’Flanagan, Ciara, Dorri, Fatemeh, Rusk, Nicole, de Algara, Teresa Ruiz, Lee, So Ra, Cheng, Brian Yu Chieh, Eirew, Peter, Kono, Takako, Pham, Jenifer, Grewal, Diljot, Lai, Daniel, Moore, Richard, Mungall, Andrew J., Marra, Marco A., McPherson, Andrew, Bouchard-Côté, Alexandre, Aparicio, Samuel, Shah, Sohrab P.

“…Progress in defining genomic fitness landscapes in cancer, especially those defined by copy number alterations (CNA), has been impeded by lack of time series…”
Get full text

Ectopic Hamartomatous Thymoma: A Review Of The Literature With Report Of New Cases And Proposal Of A New Name: Biphenotypic Branchioma by Sato, Kimiya, Thompson, Lester D. R., Miyai, Kosuke, Kono, Takako, Tsuda, Hitoshi

“…Ectopic hamartomatous thymoma (EHT) is a rare benign neoplasm of the lower neck suggesting branchial origin. Despite use of the term thymoma in the…”
Get full text

Intra-adrenal bile ductules associated with adreno-hepatic fusion: a possible origin for adrenal epithelial cysts by Matsukuma, Susumu, Kono, Takako, Takeo, Hiroaki, Sato, Kimiya

“…Aims To elucidate the relationship between the rare phenomenon of adrenal cysts and adreno‐hepatic fusion (AHF)‐related intra‐adrenal bile ductules. Methods…”
Get full text

Metachronous bilateral triple-negative breast cancer associated with neurofibromatosis type 1: A case report by Yamagishi, Yoji, Einama, Takahiro, Yamasaki, Tamio, Koiwai, Tomomi, Hiratsuka, Miyuki, Fukumura, Makiko, Kono, Takako, Ueno, Hideki, Yamamoto, Junji, Tsuda, Hitoshi

“…The present study reports a case of metachronous bilateral breast cancer associated with neurofibromatosis type 1 (NF1). A 67-year-old female, who had…”
Get full text